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Author Details
Full Name
Jon Teague
Affiliation
Wellcome Sanger Institute
ORCID
Career Start Year
2002
Papers
74
H Index
63
Expertise
CM4AI Collaborator
PMID
Paper Title
Journal Title
Published Year
36388765
Uncovering novel mutational signatures by <i>de novo</i> extraction with SigProfilerExtractor.
Cell Genom
2022
34663923
Mutational signatures in esophageal squamous cell carcinoma from eight countries with varying incidence.
Nat Genet
2021
34646017
Convergent somatic mutations in metabolism genes in chronic liver disease.
Nature
2021
29656891
Timing the Landmark Events in the Evolution of Clear Cell Renal Cell Cancer: TRACERx Renal.
Cell
2018
30304655
Classification and Personalized Prognosis in Myeloproliferative Neoplasms.
N Engl J Med
2018
29662167
Sequencing of prostate cancers identifies new cancer genes, routes of progression and drug targets.
Nat Genet
2018
29789651
Analysis of the genomic landscape of multiple myeloma highlights novel prognostic markers and disease subgroups.
Leukemia
2018
28643781
Recurrent mutation of IGF signalling genes and distinct patterns of genomic rearrangement in osteosarcoma.
Nat Commun
2017
29026114
The driver landscape of sporadic chordoma.
Nat Commun
2017
27276561
Genomic Classification and Prognosis in Acute Myeloid Leukemia.
N Engl J Med
2016
27615322
Mutational signatures of ionizing radiation in second malignancies.
Nat Commun
2016
27930809
ascatNgs: Identifying Somatically Acquired Copy-Number Alterations from Whole-Genome Sequencing Data.
Curr Protoc Bioinformatics
2016
27930805
cgpCaVEManWrapper: Simple Execution of CaVEMan in Order to Detect Somatic Single Nucleotide Variants in NGS Data.
Curr Protoc Bioinformatics
2016
27135926
Landscape of somatic mutations in 560 breast cancer whole-genome sequences.
Nature
2016
25730763
Analysis of the genetic phylogeny of multifocal prostate cancer identifies multiple independent clonal expansions in neoplastic and morphologically normal prostate tissue.
Nat Genet
2015
26647970
A comprehensive assessment of somatic mutation detection in cancer using whole-genome sequencing.
Nat Commun
2015
26678382
cgpPindel: Identifying Somatically Acquired Insertion and Deletion Events from Paired End Sequencing.
Curr Protoc Bioinformatics
2015
26678383
VAGrENT: Variation Annotation Generator.
Curr Protoc Bioinformatics
2015
26018901
Corrigendum: analysis of the genetic phylogeny of multifocal prostate cancer identifies multiple independent clonal expansions in neoplastic and morphologically normal prostate tissue.
Nat Genet
2015
24413735
RAG-mediated recombination is the predominant driver of oncogenic rearrangement in ETV6-RUNX1 acute lymphoblastic leukemia.
Nat Genet
2014
25260652
Polygenic in vivo validation of cancer mutations using transposons.
Genome Biol
2014
25271376
Origins and functional consequences of somatic mitochondrial DNA mutations in human cancer.
Elife
2014
25082706
Mobile DNA in cancer. Extensive transduction of nonrepetitive DNA mediated by L1 retrotransposition in cancer genomes.
Science
2014
24633157
Recurrent PTPRB and PLCG1 mutations in angiosarcoma.
Nat Genet
2014
24429703
Heterogeneity of genomic evolution and mutational profiles in multiple myeloma.
Nat Commun
2014
23770606
Frequent mutation of the major cartilage collagen gene COL2A1 in chondrosarcoma.
Nat Genet
2013
24325359
Somatic CALR mutations in myeloproliferative neoplasms with nonmutated JAK2.
N Engl J Med
2013
24162739
Distinct H3F3A and H3F3B driver mutations define chondroblastoma and giant cell tumor of bone.
Nat Genet
2013
24148783
The genetic heterogeneity and mutational burden of engineered melanomas in zebrafish models.
Genome Biol
2013
24030381
Clinical and biological implications of driver mutations in myelodysplastic syndromes.
Blood
2013
23630320
Single-cell paired-end genome sequencing reveals structural variation per cell cycle.
Nucleic Acids Res
2013
23778141
Whole exome sequencing of adenoid cystic carcinoma.
J Clin Invest
2013
22608083
The life history of 21 breast cancers.
Cell
2012
22722201
The landscape of cancer genes and mutational processes in breast cancer.
Nature
2012
22514011
Tandem duplication of chromosomal segments is common in ovarian and breast cancer genomes.
J Pathol
2012
22608084
Mutational processes molding the genomes of 21 breast cancers.
Cell
2012
21215367
Massive genomic rearrangement acquired in a single catastrophic event during cancer development.
Cell
2011
21995386
Somatic SF3B1 mutation in myelodysplasia with ring sideroblasts.
N Engl J Med
2011
21930507
BioMart Central Portal: an open database network for the biological community.
Database (Oxford)
2011
21248752
Exome sequencing identifies frequent mutation of the SWI/SNF complex gene PBRM1 in renal carcinoma.
Nature
2011
20016485
A comprehensive catalogue of somatic mutations from a human cancer genome.
Nature
2010
20981101
The patterns and dynamics of genomic instability in metastatic pancreatic cancer.
Nature
2010
20054297
Systematic sequencing of renal carcinoma reveals inactivation of histone modifying genes.
Nature
2010
20016488
A small-cell lung cancer genome with complex signatures of tobacco exposure.
Nature
2010
19006239
Somatic mutation databases as tools for molecular epidemiology and molecular pathology of cancer: proposed guidelines for improving data collection, distribution, and integration.
Hum Mutat
2009
19330029
Somatic mutations of the histone H3K27 demethylase gene UTX in human cancer.
Nat Genet
2009
19377476
A systematic, large-scale resequencing screen of X-chromosome coding exons in mental retardation.
Nat Genet
2009
19306394
Planning the human variome project: the Spain report.
Hum Mutat
2009
18428421
The Catalogue of Somatic Mutations in Cancer (COSMIC).
Curr Protoc Hum Genet
2008
18469813
X-linked protocadherin 19 mutations cause female-limited epilepsy and cognitive impairment.
Nat Genet
2008
1 - 50 of 74
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The University of Texas MD Anderson Cancer Center
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Andrew Menzies
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41
Patrick S Tarpey
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Sarah O'Meara
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Sarah Edkins
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Laura Mudie
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24
David C Wedge
Manchester Cancer Research Centre, University of Manchester
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Jonathan Hinton
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Serena Nik-Zainal
Early Cancer Institute, University of Cambridge
Co-authored papers
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Chris Greenman
University of East Anglia
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23
Peter Van Loo
The Francis Crick Institute
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22
Stuart McLaren
Wellcome Trust Sanger Institute
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Rebecca Shepherd
Murdoch Children's Research Institute, Royal Children's Hospital
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21
Lucy A Stebbings
Wellcome Trust Sanger Institute
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Ludmil B Alexandrov
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