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Author Details

Christopher H van Dyck
Yale University School of Medicine
1990
170
66
PMIDPaper TitleJournal TitlePublished Year
37673749Assessment of Gray Matter Microstructure and Synaptic Density in Alzheimer's Disease: A Multimodal Imaging Study With DTI and SV2A PET.Am J Geriatr Psychiatry2024
37955791The regional pattern of age-related synaptic loss in the human brain differs from gray matter volume loss: in vivo PET measurement with [<sup>11</sup>C]UCB-J.Eur J Nucl Med Mol Imaging2024
36449413Lecanemab in Early Alzheimer's Disease.N Engl J Med2023
37693474Sex differences in the pleiotropy of hearing difficulty with imaging-derived phenotypes: a brain-wide investigation.medRxiv2023
38042785Aging gene signature of memory CD8<sup>+</sup> T cells is associated with neurocognitive functioning in Alzheimer's disease.Immun Ageing2023
37538343Effects of methylphenidate on neuropsychiatric symptoms in Alzheimer's disease: Evidence from the ADMET 2 study.Alzheimers Dement (N Y)2023
37874022Localization of PDE4D, HCN1 channels, and mGluR3 in rhesus macaque entorhinal cortex may confer vulnerability in Alzheimer's disease.Cereb Cortex2023
37458272Trial of Solanezumab in Preclinical Alzheimer's Disease.N Engl J Med2023
37422964Principal component analysis of synaptic density measured with [<sup>11</sup>C]UCB-J PET in early Alzheimer's disease.Neuroimage Clin2023
37187779Disease severity and minimal clinically important differences in clinical outcome assessments for Alzheimer's disease clinical trials.Alzheimers Dement (N Y)2023
36946443Investigating Partially Discordant Results in Phase 3 Studies of Aducanumab.J Prev Alzheimers Dis2023
37382240Relationships of in vivo brain norepinephrine transporter and age, BMI, and gender.Synapse2023
37099355Lecanemab in Early Alzheimer's Disease. Reply.N Engl J Med2023
37099351Lecanemab in Early Alzheimer's Disease.N Engl J Med2023
37066690Cost consequence analysis of Apathy in Dementia Methylphenidate Trial 2 (ADMET 2).Int Psychogeriatr2023
37066364Aging gene signature of IL-7 receptor alpha low effector memory CD8<sup>+</sup> T cells is associated with neurocognitive functioning in Alzheimer's disease.Res Sq2023
36599073Response to: Multiple Cerebral Hemorrhages in a Patient Receiving Lecanemab and Treated with t-PA for Stroke.N Engl J Med2023
36526112Aging of the brain in bipolar disorder: Illness- and onset-related effects in cortical thickness and subcortical gray matter volume.J Affect Disord2023
36627206Natural cubic splines for the analysis of Alzheimer's clinical trials.Pharm Stat2023
34924392Cerebral Volumetric Correlates of Apathy in Alzheimer's Disease and Cognitively Normal Older Adults: Meta-Analysis, Label-Based Review, and Study of an Independent Cohort.J Alzheimers Dis2022
35581440Alzheimer disease neuropathology in a patient previously treated with aducanumab.Acta Neuropathol2022
35542991Two Randomized Phase 3 Studies of Aducanumab in Early Alzheimer's Disease.J Prev Alzheimers Dis2022
35357236Emotion Processing Dysfunction in Alzheimer's Disease: An Overview of Behavioral Findings, Systems Neural Correlates, and Underlying Neural Biology.Am J Alzheimers Dis Other Demen2022
36314209Hypothalamic Functional Connectivity and Apathy in People with Alzheimer's Disease and Cognitively Normal Healthy Controls.J Alzheimers Dis2022
35907208Aging the brain: multi-region methylation principal component based clock in the context of Alzheimer's disease.Aging (Albany NY)2022
36371232Performance of a fully-automated Lumipulse plasma phospho-tau181 assay for Alzheimer's disease.Alzheimers Res Ther2022
36121669Evaluating the Safety and Efficacy of Crenezumab vs Placebo in Adults With Early Alzheimer Disease: Two Phase 3 Randomized Placebo-Controlled Trials.JAMA Neurol2022
35174954Synaptic density and cognitive performance in Alzheimer's disease: A PET imaging study with [<sup>11</sup> C]UCB-J.Alzheimers Dement2022
34963063Association of entorhinal cortical tau deposition and hippocampal synaptic density in older individuals with normal cognition and early Alzheimer's disease.Neurobiol Aging2022
32461027Neurobiologic Rationale for Treatment of Apathy in Alzheimer's Disease With Methylphenidate.Am J Geriatr Psychiatry2021
33829643Age-related calcium dysregulation linked with tau pathology and impaired cognition in non-human primates.Alzheimers Dement2021
33766236Amyloid-Associated Depression-or Not?Biol Psychiatry2021
33757318Comparison of [<sup>11</sup>C]UCB-J and [<sup>18</sup>F]FDG PET in Alzheimer's disease: A tracer kinetic modeling study.J Cereb Blood Flow Metab2021
33831179Pleiotropic effects of telomere length loci with brain morphology and brain tissue expression.Hum Mol Genet2021
34430703Feasibility study for detection of retinal amyloid in clinical trials: The Anti-Amyloid Treatment in Asymptomatic Alzheimer's Disease (A4) trial.Alzheimers Dement (Amst)2021
34570180Effect of Methylphenidate on Apathy in Patients With Alzheimer Disease: The ADMET 2 Randomized Clinical Trial.JAMA Neurol2021
34482052Cognitive dysfunction and cerebral volumetric deficits in individuals with Alzheimer's disease, alcohol use disorder, and dual diagnosis.Psychiatry Res Neuroimaging2021
34224153Generation of synthetic PET images of synaptic density and amyloid from <sup>18</sup> F-FDG images using deep learning.Med Phys2021
34155411A trial of gantenerumab or solanezumab in dominantly inherited Alzheimer's disease.Nat Med2021
34297895Recruitment of a multi-site randomized controlled trial of aerobic exercise for older adults with amnestic mild cognitive impairment: The EXERT trial.Alzheimers Dement2021
34119639Partial volume correction analysis for <sup>11</sup>C-UCB-J PET studies of Alzheimer's disease.Neuroimage2021
34052464Effect of age on brain metabotropic glutamate receptor subtype 5 measured with [[18]F]FPEB PET.Neuroimage2021
34000404Identifying brain networks in synaptic density PET (<sup>11</sup>C-UCB-J) with independent component analysis.Neuroimage2021
33402201Association of Aβ deposition and regional synaptic density in early Alzheimer's disease: a PET imaging study with [<sup>11</sup>C]UCB-J.Alzheimers Res Ther2021
33047474Alzheimer's &amp; Dementia: The Journal of the Alzheimer's Association.Alzheimers Dement2021
32646875Simplified Quantification of <sup>11</sup>C-UCB-J PET Evaluated in a Large Human Cohort.J Nucl Med2021
32565008Measuring Apathy in Alzheimer's Disease in the Apathy in Dementia Methylphenidate Trial 2 (ADMET 2): A Comparison of Instruments.Am J Geriatr Psychiatry2021
32400950In vivo measurement of widespread synaptic loss in Alzheimer's disease with SV2A PET.Alzheimers Dement2020
31906973Classical complement cascade initiating C1q protein within neurons in the aged rhesus macaque dorsolateral prefrontal cortex.J Neuroinflammation2020
32053667Cognitively unimpaired adults' reactions to disclosure of amyloid PET scan results.PLoS One2020
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Collaborators

National Institute of Mental Health
Co-authored papers 31
Alzheimer's Therapeutic Research Institute, University of Southern California
Co-authored papers 18
Yale University
Co-authored papers 16
University of California
Co-authored papers 13
Alzheimer's Disease Research Unit, Yale University School of Medicine
Co-authored papers 12
Mayo Clinic Rochester
Co-authored papers 10
University of Rochester, University of Rochester Medical Center
Co-authored papers 9
Inc., Medical University of South Carolina
Co-authored papers 9
Butler Hospital, and Warren Alpert Medical School of Brown University
Co-authored papers 8
F. Hoffmann-La Roche Ltd
Co-authored papers 7
Mayo Clinic Rochester
Co-authored papers 7
Co-authored papers 7
Icahn School of Medicine at Mount Sinai
Co-authored papers 7
Emory University School of Medicine
Co-authored papers 6
Case Western Reserve University
Co-authored papers 6
Wake Forest University School of Medicine
Co-authored papers 6
Oregon Center for Aging & Technology
Co-authored papers 5
Brigham and Women's Hospital, Massachusetts General Hospital
Co-authored papers 5
University of Texas Southwestern Medical Center
Co-authored papers 5
Barrow Neurological Institute
Co-authored papers 5
Co-authored papers 5
Alzheimer's Therapeutic Research Institute, University of Southern California
Co-authored papers 5
University of California
Co-authored papers 5
Mallinckrodt Institute of Radiology , Washington University School of Medicine
Co-authored papers 4
University of Michigan ann arbor
Co-authored papers 4
University of California
Co-authored papers 4
Goizueta Alzheimer's Disease Research Center, Emory University School of Medicine
Co-authored papers 4
Banner Alzheimer's Institute
Co-authored papers 4
Stark Neurosciences Research Institute, Indiana University School of Medicine (IUSM)
Co-authored papers 4
Washington University School of Medicine
Co-authored papers 4