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Author Details

Iain M Wallace
Novartis Institutes for BioMedical Research
2005
26
17
Andrej Sali (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
30824200Discovery of a small molecule RXFP3/4 agonist that increases food intake in rats upon acute central administration.Bioorg Med Chem Lett2019
28917822CHEMGENIE: integration of chemogenomics data for applications in chemical biology.Drug Discov Today2018
27800551Open Source Drug Discovery: Highly Potent Antimalarial Compounds Derived from the Tres Cantos Arylpyrroles.ACS Cent Sci2016
26479441Dark chemical matter as a promising starting point for drug lead discovery.Nat Chem Biol2015
24246376Application of Titration-Based Screening for the Rapid Pilot Testing of High-Throughput Assays.J Biomol Screen2014
24723613Mapping the cellular response to small molecules using chemogenomic fitness signatures.Science2014
24292071PITPs as targets for selectively interfering with phosphoinositide signaling in cells.Nat Chem Biol2014
23797109Miniature short hairpin RNA screens to characterize antiproliferative drugs.G3 (Bethesda)2013
24098102Target prediction for an open access set of compounds active against Mycobacterium tuberculosis.PLoS Comput Biol2013
23158586A phenotypic screening platform to identify small molecule modulators of Chlamydomonas reinhardtii growth, motility and photosynthesis.Genome Biol2012
21698101Design, synthesis and characterization of a highly effective inhibitor for analog-sensitive (as) kinases.PLoS One2011
22057127Dafadine inhibits DAF-9 to promote dauer formation and longevity of Caenorhabditis elegans.Nat Chem Biol2011
22035796Compound prioritization methods increase rates of chemical probe discovery in model organisms.Chem Biol2011
21877291Displaying chemical information on a biological network using Cytoscape.Methods Mol Biol2011
20093466The genetic landscape of a cell.Science2010
20512140A predictive model for drug bioaccumulation and bioactivity in Caenorhabditis elegans.Nat Chem Biol2010
20460461Highly-multiplexed barcode sequencing: an efficient method for parallel analysis of pooled samples.Nucleic Acids Res2010
18450519Fast embedding methods for clustering tens of thousands of sequences.Comput Biol Chem2008
17451607Supervised multivariate analysis of sequence groups to identify specificity determining residues.BMC Bioinformatics2007
17526519The M-Coffee web server: a meta-method for computing multiple sequence alignments by combining alternative alignment methods.Nucleic Acids Res2007
17846036Clustal W and Clustal X version 2.0.Bioinformatics2007
16556910M-Coffee: combining multiple sequence alignment methods with T-Coffee.Nucleic Acids Res2006
16922695Analysis and comparison of benchmarks for multiple sequence alignment.In Silico Biol2006
15564300Evaluation of iterative alignment algorithms for multiple alignment.Bioinformatics2005
16027352Mind the gaps: progress in progressive alignment.Proc Natl Acad Sci U S A2005
15963889Multiple sequence alignments.Curr Opin Struct Biol2005
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Collaborators

Gary D Bader
University of Toronto
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Lawrence E Heisler
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University of Toronto
Co-authored papers 3
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European Molecular Biology Laboratory - European Bioinformatics Institute
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Franck Valentin
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Lewis-Sigler Institute for Integrative Genomics, Princeton University
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Anne-Claude Gingras
Lunenfeld-Tanenbaum Research Institute
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Michael Brudno
University of Toronto
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Stuart A Ralph
Bio21 Molecular Science and Biotechnology Institute, University of Melbourne
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Michael Costanzo
Co-authored papers 1
Brenda J Andrews
University of Toronto
Co-authored papers 1
Chad L Myers
University of Minnesota - Twin Cities
Co-authored papers 1
Franco J Vizeacoumar
College of Medicine, University of Saskatchewan
Co-authored papers 1
Quaid Morris
Sloan Kettering Institute
Co-authored papers 1
Francesc Posas
Universitat Pompeu Fabra
Co-authored papers 1
Eula Fung
Stanford University School of Medicine
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Release 1.2