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Author Details
Full Name
Yonghong Xiao
Affiliation
TESARO Inc.
ORCID
Career Start Year
1993
Papers
35
H Index
30
Expertise
CM4AI Collaborator
PMID
Paper Title
Journal Title
Published Year
29625050
Oncogenic Signaling Pathways in The Cancer Genome Atlas.
Cell
2018
29617664
Genomic and Molecular Landscape of DNA Damage Repair Deficiency across The Cancer Genome Atlas.
Cell Rep
2018
28085948
Correction: Preclinical Evidence of Anti-Tumor Activity Induced by EZH2 Inhibition in Human Models of Synovial Sarcoma.
PLoS One
2017
27391784
Preclinical Evidence of Anti-Tumor Activity Induced by EZH2 Inhibition in Human Models of Synovial Sarcoma.
PLoS One
2016
24563539
Selective inhibition of EZH2 by EPZ-6438 leads to potent antitumor activity in EZH2-mutant non-Hodgkin lymphoma.
Mol Cancer Ther
2014
25024180
Copy number alteration burden predicts prostate cancer relapse.
Proc Natl Acad Sci U S A
2014
23776040
ZNF365 promotes stability of fragile sites and telomeres.
Cancer Discov
2013
22341455
Telomerase reactivation following telomere dysfunction yields murine prostate tumors with bone metastases.
Cell
2012
23074196
Integrative functional genomics identifies RINT1 as a novel GBM oncogene.
Neuro Oncol
2012
22751500
STAR RNA-binding protein Quaking suppresses cancer via stabilization of specific miRNA.
Genes Dev
2012
22750848
microRNA regulatory network inference identifies miR-34a as a novel regulator of TGF-β signaling in glioblastoma.
Cancer Discov
2012
22541435
Oncogenic Kras maintains pancreatic tumors through regulation of anabolic glucose metabolism.
Cell
2012
21289624
SMAD4-dependent barrier constrains prostate cancer growth and metastatic progression.
Nature
2011
21984975
PTEN is a major tumor suppressor in pancreatic ductal adenocarcinoma and regulates an NF-κB-cytokine network.
Cancer Discov
2011
21602815
Clear-cell papillary renal cell carcinoma: molecular and immunohistochemical analysis with emphasis on the von Hippel-Lindau gene and hypoxia-inducible factor pathway-related proteins.
Mod Pathol
2011
21741599
Proinvasion metastasis drivers in early-stage melanoma are oncogenes.
Cancer Cell
2011
21741596
Selective killing of mixed lineage leukemia cells by a potent small-molecule DOT1L inhibitor.
Cancer Cell
2011
21368833
SCF(FBW7) regulates cellular apoptosis by targeting MCL1 for ubiquitylation and destruction.
Nature
2011
20351267
Mig-6 controls EGFR trafficking and suppresses gliomagenesis.
Proc Natl Acad Sci U S A
2010
20520718
Integrative genome comparison of primary and metastatic melanomas.
PLoS One
2010
20478531
PLAGL2 regulates Wnt signaling to impede differentiation in neural stem cells and gliomas.
Cancer Cell
2010
20534551
Pattern of retinoblastoma pathway inactivation dictates response to CDK4/6 inhibition in GBM.
Proc Natl Acad Sci U S A
2010
20579941
Integrative genomic profiling of human prostate cancer.
Cancer Cell
2010
19553991
GOLPH3 modulates mTOR signalling and rapamycin sensitivity in cancer.
Nature
2009
17998335
Disruption of the Fbxw8 gene results in pre- and postnatal growth retardation in mice.
Mol Cell Biol
2008
19050074
Genomic alterations link Rho family of GTPases to the highly invasive phenotype of pancreas cancer.
Proc Natl Acad Sci U S A
2008
18394558
Feedback circuit among INK4 tumor suppressors constrains human glioblastoma development.
Cancer Cell
2008
17254969
FoxOs are lineage-restricted redundant tumor suppressors and regulate endothelial cell homeostasis.
Cell
2007
18006816
Common and distinct genomic events in sporadic colorectal cancer and diverse cancer types.
Cancer Res
2007
9008167
Association of BRCA1 with Rad51 in mitotic and meiotic cells.
Cell
1997
9224597
Conditional gene targeted deletion by Cre recombinase demonstrates the requirement for the double-strand break repair Mre11 protein in murine embryonic stem cells.
Nucleic Acids Res
1997
8655595
Control of retinoic acid receptor expression in mouse melanoma cells by cyclic AMP.
J Cell Physiol
1996
7623824
DNA ligase I mediates essential functions in mammalian cells.
Mol Cell Biol
1995
7775578
Regulation of a muscle-specific transgene by retinoic acid.
J Cell Biol
1995
8234321
Gene targeting of X chromosome-linked chronic granulomatous disease locus in a human myeloid leukemia cell line and rescue by expression of recombinant gp91phox.
Proc Natl Acad Sci U S A
1993
1 - 35 of 35
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