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Author Details

Yonghong Xiao
TESARO Inc.
1993
35
30
PMIDPaper TitleJournal TitlePublished Year
29625050Oncogenic Signaling Pathways in The Cancer Genome Atlas.Cell2018
29617664Genomic and Molecular Landscape of DNA Damage Repair Deficiency across The Cancer Genome Atlas.Cell Rep2018
28085948Correction: Preclinical Evidence of Anti-Tumor Activity Induced by EZH2 Inhibition in Human Models of Synovial Sarcoma.PLoS One2017
27391784Preclinical Evidence of Anti-Tumor Activity Induced by EZH2 Inhibition in Human Models of Synovial Sarcoma.PLoS One2016
24563539Selective inhibition of EZH2 by EPZ-6438 leads to potent antitumor activity in EZH2-mutant non-Hodgkin lymphoma.Mol Cancer Ther2014
25024180Copy number alteration burden predicts prostate cancer relapse.Proc Natl Acad Sci U S A2014
23776040ZNF365 promotes stability of fragile sites and telomeres.Cancer Discov2013
22341455Telomerase reactivation following telomere dysfunction yields murine prostate tumors with bone metastases.Cell2012
23074196Integrative functional genomics identifies RINT1 as a novel GBM oncogene.Neuro Oncol2012
22751500STAR RNA-binding protein Quaking suppresses cancer via stabilization of specific miRNA.Genes Dev2012
22750848microRNA regulatory network inference identifies miR-34a as a novel regulator of TGF-β signaling in glioblastoma.Cancer Discov2012
22541435Oncogenic Kras maintains pancreatic tumors through regulation of anabolic glucose metabolism.Cell2012
21289624SMAD4-dependent barrier constrains prostate cancer growth and metastatic progression.Nature2011
21984975PTEN is a major tumor suppressor in pancreatic ductal adenocarcinoma and regulates an NF-κB-cytokine network.Cancer Discov2011
21602815Clear-cell papillary renal cell carcinoma: molecular and immunohistochemical analysis with emphasis on the von Hippel-Lindau gene and hypoxia-inducible factor pathway-related proteins.Mod Pathol2011
21741599Proinvasion metastasis drivers in early-stage melanoma are oncogenes.Cancer Cell2011
21741596Selective killing of mixed lineage leukemia cells by a potent small-molecule DOT1L inhibitor.Cancer Cell2011
21368833SCF(FBW7) regulates cellular apoptosis by targeting MCL1 for ubiquitylation and destruction.Nature2011
20351267Mig-6 controls EGFR trafficking and suppresses gliomagenesis.Proc Natl Acad Sci U S A2010
20520718Integrative genome comparison of primary and metastatic melanomas.PLoS One2010
20478531PLAGL2 regulates Wnt signaling to impede differentiation in neural stem cells and gliomas.Cancer Cell2010
20534551Pattern of retinoblastoma pathway inactivation dictates response to CDK4/6 inhibition in GBM.Proc Natl Acad Sci U S A2010
20579941Integrative genomic profiling of human prostate cancer.Cancer Cell2010
19553991GOLPH3 modulates mTOR signalling and rapamycin sensitivity in cancer.Nature2009
17998335Disruption of the Fbxw8 gene results in pre- and postnatal growth retardation in mice.Mol Cell Biol2008
19050074Genomic alterations link Rho family of GTPases to the highly invasive phenotype of pancreas cancer.Proc Natl Acad Sci U S A2008
18394558Feedback circuit among INK4 tumor suppressors constrains human glioblastoma development.Cancer Cell2008
17254969FoxOs are lineage-restricted redundant tumor suppressors and regulate endothelial cell homeostasis.Cell2007
18006816Common and distinct genomic events in sporadic colorectal cancer and diverse cancer types.Cancer Res2007
9008167Association of BRCA1 with Rad51 in mitotic and meiotic cells.Cell1997
9224597Conditional gene targeted deletion by Cre recombinase demonstrates the requirement for the double-strand break repair Mre11 protein in murine embryonic stem cells.Nucleic Acids Res1997
8655595Control of retinoic acid receptor expression in mouse melanoma cells by cyclic AMP.J Cell Physiol1996
7623824DNA ligase I mediates essential functions in mammalian cells.Mol Cell Biol1995
7775578Regulation of a muscle-specific transgene by retinoic acid.J Cell Biol1995
8234321Gene targeting of X chromosome-linked chronic granulomatous disease locus in a human myeloid leukemia cell line and rescue by expression of recombinant gp91phox.Proc Natl Acad Sci U S A1993
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Yale University School of Medicine
Co-authored papers 3
Department of Biology at Brigham Young University
Co-authored papers 2
Dartmouth College Geisel School of Medicine, Princeton University, University of Colorado Anschutz Medical Campus, University of Pennsylvania Perelman School of Medicine
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