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Author Details

Sheila K Singh
McMaster University
2001
129
31
PMIDPaper TitleJournal TitlePublished Year
37787999Intratumoral Delivery of Chimeric Antigen Receptor T Cells Targeting CD133 Effectively Treats Brain Metastases.Clin Cancer Res2024
34784622Comparison of Two Drainage Systems on Chronic Subdural Hematoma Recurrence.J Neurol Surg A Cent Eur Neurosurg2023
37354357An effective kinase inhibition strategy for metastatic recurrent childhood medulloblastoma.J Neurooncol2023
37420311Compensatory cross-talk between autophagy and glycolysis regulates senescence and stemness in heterogeneous glioblastoma tumor subpopulations.Acta Neuropathol Commun2023
37343514Safety and efficacy of lorlatinib against ALK-driven refractory or relapsed neuroblastoma.Cell Rep Med2023
37130865Metabolism-based targeting of MYC via MPC-SOD2 axis-mediated oxidation promotes cellular differentiation in group 3 medulloblastoma.Nat Commun2023
37430373Dynamic profiling of medulloblastoma surfaceome.Acta Neuropathol Commun2023
36780531An HLA-G/SPAG9/STAT3 axis promotes brain metastases.Proc Natl Acad Sci U S A2023
36627300Author Correction: Characterization of an RNA binding protein interactome reveals a context-specific post-transcriptional landscape of MYC-amplified medulloblastoma.Nat Commun2023
33870664A single center experience in the management of progressive juvenile pilocytic astrocytoma.J Neurosurg Sci2023
35119267Discovery of HDAC6-Selective Inhibitor NN-390 with <i>in Vitro</i> Efficacy in Group 3 Medulloblastoma.J Med Chem2022
35463317The Role of a Longitudinal, Multidisciplinary Clinic in Building a Unique Research Collaborative.Front Oncol2022
36473869Characterization of an RNA binding protein interactome reveals a context-specific post-transcriptional landscape of MYC-amplified medulloblastoma.Nat Commun2022
35874663Dual Antigen T Cell Engagers Targeting CA9 as an Effective Immunotherapeutic Modality for Targeting CA9 in Solid Tumors.Front Immunol2022
36178522The proteomic landscape of glioblastoma recurrence reveals novel and targetable immunoregulatory drivers.Acta Neuropathol2022
36368321Cancer-selective metabolic vulnerabilities in MYC-amplified medulloblastoma.Cancer Cell2022
36035806Derivation and culturing of neural stem cells from human embryonic brain tissue.STAR Protoc2022
35990706Reoperation in adult patients with recurrent glioblastoma: A matched cohort analysis.Neurooncol Adv2022
36170831Characterization of the minimal residual disease state reveals distinct evolutionary trajectories of human glioblastoma.Cell Rep2022
35017149CD70 as an actionable immunotherapeutic target in recurrent glioblastoma and its microenvironment.J Immunother Cancer2022
35155252The Road to CAR T-Cell Therapies for Pediatric CNS Tumors: Obstacles and New Avenues.Front Oncol2022
34978683Childhood Medulloblastoma: An Overview.Methods Mol Biol2022
34298615Advances in Immunotherapy for Adult Glioblastoma.Cancers (Basel)2021
33489908The Strange Case of Jekyll and Hyde: Parallels Between Neural Stem Cells and Glioblastoma-Initiating Cells.Front Oncol2021
33672811ETS-Domain Transcription Factor Elk-1 Regulates Stemness Genes in Brain Tumors and CD133+ BrainTumor-Initiating Cells.J Pers Med2021
34878832Temporal profiling of therapy resistance in human medulloblastoma identifies novel targetable drivers of recurrence.Sci Adv2021
34765972Identification of five important genes to predict glioblastoma subtypes.Neurooncol Adv2021
34761232<i>In vitro</i> evaluation of CAR-T cells in patient-derived glioblastoma models.STAR Protoc2021
31612572Analysis of factors that influence neurosurgical length of hospital stay among newly diagnosed pediatric brain tumor patients.Pediatr Blood Cancer2020
31695152A CD133-AKT-Wnt signaling axis drives glioblastoma brain tumor-initiating cells.Oncogene2020
33377073A Patient-Derived Xenograft Model of Glioblastoma.STAR Protoc2020
33377068Preclinical Testing of CAR T Cells in a Patient-Derived Xenograft Model of Glioblastoma.STAR Protoc2020
33377018Assessing the Safety of a Cell-Based Immunotherapy for Brain Cancers Using a Humanized Model of Hematopoiesis.STAR Protoc2020
33281826Strategies to Enhance the Efficacy of T-Cell Therapy for Central Nervous System Tumors.Front Immunol2020
33138032RAD51-Mediated DNA Homologous Recombination Is Independent of <i>PTEN</i> Mutational Status.Cancers (Basel)2020
33241114WNT: an unexpected tumor suppressor in medulloblastoma.Mol Cell Oncol2020
33149194De novo necroptosis creates an inflammatory environment mediating tumor susceptibility to immune checkpoint inhibitors.Commun Biol2020
32859895Wnt activation as a therapeutic strategy in medulloblastoma.Nat Commun2020
32445698Metabolic Regulation of the Epigenome Drives Lethal Infantile Ependymoma.Cell2020
32417652Development of a peptide-based delivery platform for targeting malignant brain tumors.Biomaterials2020
32464096The Rational Development of CD133-Targeting Immunotherapies for Glioblastoma.Cell Stem Cell2020
30593514TAp73 Modifies Metabolism and Positively Regulates Growth of Cancer Stem-Like Cells in a Redox-Sensitive Manner.Clin Cancer Res2019
31466905Predictive measures and outcomes of extent of resection in juvenile pilocytic astrocytoma.J Clin Neurosci2019
31293232Salvage Therapy for Childhood Medulloblastoma: A Single Center Experience.Can J Neurol Sci2019
31541226Deciphering brain tumor heterogeneity, one cell at a time.Nat Med2019
31115870Bmi1 regulates human glioblastoma stem cells through activation of differential gene networks in CD133+ brain tumor initiating cells.J Neurooncol2019
30849274Regulation of the proline regulatory axis and autophagy modulates stemness in TP73/p73 deficient cancer stem-like cells.Autophagy2019
30324527In Vivo Murine Models of Brain Metastasis.Methods Mol Biol2019
30324524In Vitro Assays for Screening Small Molecules.Methods Mol Biol2019
30324522EPH Profiling of BTIC Populations in Glioblastoma Multiforme Using CyTOF.Methods Mol Biol2019
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Collaborators

Chitra Venugopal
McMaster Stem Cell and Cancer Research Institute
Co-authored papers 69
Chirayu Chokshi
McMaster University
Co-authored papers 19
Jason Moffat
University of Toronto
Co-authored papers 15
John Provias
McMaster University
Co-authored papers 12
Nazanin Tatari
McMaster University
Co-authored papers 12
Kevin R Brown
College Street, University of Toronto
Co-authored papers 10
Cynthia Hawkins
The Hospital for Sick Children
Co-authored papers 8
Dillon McKenna
McMaster University
Co-authored papers 8
Peter B Dirks
The Hospital for Sick Children, University of Toronto
Co-authored papers 7
Michael D Taylor
The Hospital for Sick Children
Co-authored papers 7
Bradley W Doble
Co-authored papers 6
Farshad Nassiri
Toronto Western Hospital, University Health Network, University of Toronto
Co-authored papers 5
Xin Wang
The Chinese University of Hong Kong, Prince of Wales Hospital
Co-authored papers 5
Vijay Ramaswamy
Hospital for Sick Children
Co-authored papers 4
Boleslaw Lach
McMaster University
Co-authored papers 4
Thomas Kislinger
Princess Margaret Cancer Centre, University Health Network, University of Toronto
Co-authored papers 4
Shahrad Rod Rassekh
British Columbia Children's Hospital, The University of British Columbia
Co-authored papers 4
Ian D Clarke
Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children
Co-authored papers 3
Mathieu Lupien
Princess Margaret Cancer Research Centre
Co-authored papers 3
Gary D Bader
University of Toronto
Co-authored papers 3
J??ri Reimand
Ontario Institute for Cancer Research
Co-authored papers 3
Paul A Northcott
St Jude Children's Research Hospital
Co-authored papers 3
Stephen C Mack
St Jude Children's Research Hospital
Co-authored papers 3
Igor Jurisica
Schroeder Arthritis Institute
Co-authored papers 3
Anna Dvorkin-Gheva
McMaster University
Co-authored papers 3
Michael D Cusimano
St. Michael's Hospital, University of Toronto
Co-authored papers 3
Anca Sorana Morrissy
Cumming School of Medicine, University of Calgary
Co-authored papers 3
Hamza Farooq
BioBox Analytics Inc.
Co-authored papers 3
James T Rutka
Hospital for Sick Children
Co-authored papers 3
Betty Luu
University of Wollongong
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Release 1.2