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Author Details

Malia B Potts
St. Jude Children's Research Hospital
2004
19
10
Trey Ideker (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36400000How to kill an ERKsome target: PROTACs deliver the deathblow.Cell Chem Biol2022
35644338FANCL supports Parkin-mediated mitophagy in a ubiquitin ligase-independent manner.Biochim Biophys Acta Mol Basis Dis2022
34077419The nonreceptor tyrosine kinase SRMS inhibits autophagy and promotes tumor growth by phosphorylating the scaffolding protein FKBP51.PLoS Biol2021
33101709MEKK3-MEK5-ERK5 signaling promotes mitochondrial degradation.Cell Death Discov2020
30611980Identification of substituted 5-membered heterocyclic compounds as potential anti-leukemic agents.Eur J Med Chem2019
31378711A Genome-wide Functional Signature Ontology Map and Applications to Natural Product Mechanism of Action Discovery.Cell Chem Biol2019
31084028Studies of Jatrogossone A as a Reactive Oxygen Species Inducer in Cancer Cellular Models.J Nat Prod2019
28294973FUSION-Guided Hypothesis Development Leads to the Identification of N⁶,N⁶-Dimethyladenosine, a Marine-Derived AKT Pathway Inhibitor.Mar Drugs2017
27426302Discovery of novel TAOK2 inhibitor scaffolds from high-throughput screening.Bioorg Med Chem Lett2016
25679763Degradation of AMPK by a cancer-specific ubiquitin ligase.Cell2015
26655797A genome-scale screen reveals context-dependent ovarian cancer sensitivity to miRNA overexpression.Mol Syst Biol2015
25867045Mode of action and pharmacogenomic biomarkers for exceptional responders to didemnin B.Nat Chem Biol2015
23984625Discoipyrroles A-D: isolation, structure determination, and synthesis of potent migration inhibitors from Bacillus hunanensis.J Am Chem Soc2013
24129700Using functional signature ontology (FUSION) to identify mechanisms of action for natural products.Sci Signal2013
21150934Cell lineage and cell death: Caenorhabditis elegans and cancer research.Nat Rev Cancer2011
19254707Trithorax, Hox, and TALE-class homeodomain proteins ensure cell survival through repression of the BH3-only gene egl-1.Dev Biol2009
16421192Direct regulation of egl-1 and of programmed cell death by the Hox protein MAB-5 and by CEH-20, a C. elegans homolog of Pbx1.Development2006
16344307Reduced Apaf-1 levels in cardiomyocytes engage strict regulation of apoptosis by endogenous XIAP.J Cell Biol2005
15542838Bcr-Abl-mediated protection from apoptosis downstream of mitochondrial cytochrome c release.Mol Cell Biol2004
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Collaborators

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University of Texas Southwestern Medical Center
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The University of Texas MD Anderson Cancer Center
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University of North Carolina at Chapel Hill
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St. Jude Children's Research Hospital
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