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| 34648031 | NCATS Inxight Drugs: a comprehensive and curated portal for translational research. | Nucleic Acids Res | 2022 |
| 36229506 | Author Correction: A high-throughput screening platform for Polycystic Kidney Disease (PKD) drug repurposing utilizing murine and human ADPKD cells. | Sci Rep | 2022 |
| 35696646 | Discovery and Optimization of Pyrrolopyrimidine Derivatives as Selective Disruptors of the Perinucleolar Compartment, a Marker of Tumor Progression toward Metastasis. | J Med Chem | 2022 |
| 35787375 | A quantitative high-throughput screen identifies compounds that lower expression of the SCA2-and ALS-associated gene ATXN2. | Journal of Biological Chemistry | 2022 |
| 35041689 | A platform of assays for the discovery of anti-Zika small-molecules with activity in a 3D-bioprinted outer-blood-retina model. | PLoS One | 2022 |
| 34500187 | Kinetic and structural investigations of novel inhibitors of human epithelial 15-lipoxygenase-2. | Bioorg Med Chem | 2021 |
| 34075120 | Identification of Small Molecule Inhibitors of a Mir155 Transcriptional Reporter in Th17 Cells. | Sci Rep | 2021 |
| 33910017 | A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome. | Cell Reports | 2021 |
| 33483532 | Chemoprotective antimalarials identified through quantitative high-throughput screening of Plasmodium blood and liver stage parasites. | Sci Rep | 2021 |
| 33771585 | Optimization of ether and aniline based inhibitors of lactate dehydrogenase. | Bioorganic and Medicinal Chemistry Letters | 2021 |
| 33822623 | Discovery and Optimization of 2<i>H</i>-1λ<sup>2</sup>-Pyridin-2-one Inhibitors of Mutant Isocitrate Dehydrogenase 1 for the Treatment of Cancer. | J Med Chem | 2021 |
| 33919707 | FEN1 Blockade for Platinum Chemo-Sensitization and Synthetic Lethality in Epithelial Ovarian Cancers. | Cancers | 2021 |
| 34520759 | The AKT modulator A-443654 reduces α-synuclein expression and normalizes ER stress and autophagy. | Journal of Biological Chemistry | 2021 |
| 31522598 | Identification of Activators of Human Fumarate Hydratase by Quantitative High-Throughput Screening. | SLAS Discov | 2020 |
| 32144367 | A high-throughput screening platform for Polycystic Kidney Disease (PKD) drug repurposing utilizing murine and human ADPKD cells. | Sci Rep | 2020 |
| 32193286 | Endonuclease FEN1 Coregulates ERα Activity and Provides a Novel Drug Interface in Tamoxifen-Resistant Breast Cancer. | Cancer Res | 2020 |
| 32111885 | Anxiolytic Drug FGIN-1-27 Ameliorates Autoimmunity by Metabolic Reprogramming of Pathogenic Th17 Cells. | Sci Rep | 2020 |
| 31939288 | Characterization of Lead Compounds Targeting the Selenoprotein Thioredoxin Glutathione Reductase for Treatment of Schistosomiasis. | ACS Infectious Diseases | 2020 |
| 32231230 | Identification of Small Molecule Enhancers of Immunotherapy for Melanoma. | Sci Rep | 2020 |
| 31662025 | A Comparative Study of Target Engagement Assays for HDAC1 Inhibitor Profiling. | SLAS Discovery | 2020 |
| 32525297 | Optimization of High-Throughput Methyltransferase Assays for the Discovery of Small Molecule Inhibitors. | ACS Combinatorial Science | 2020 |
| 33229545 | Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors. | Proceedings of the National Academy of Sciences of the United States of America | 2020 |
| 32902275 | Pyrazole-Based Lactate Dehydrogenase Inhibitors with Optimized Cell Activity and Pharmacokinetic Properties. | J Med Chem | 2020 |
| 31532656 | Scaffold-Based Analytics: Enabling Hit-to-Lead Decisions by Visualizing Chemical Series Linked across Large Datasets. | J Chem Inf Model | 2019 |
| 30625228 | A high-throughput screen to identify novel small molecule inhibitors of the Werner Syndrome Helicase-Nuclease (WRN). | PLoS ONE | 2019 |
| 31133849 | The NCATS BioPlanet - An Integrated Platform for Exploring the Universe of Cellular Signaling Pathways for Toxicology, Systems Biology, and Chemical Genomics. | Front Pharmacol | 2019 |
| 30753830 | KDM5 Histone Demethylase Activity Links Cellular Transcriptomic Heterogeneity to Therapeutic Resistance. | Cancer Cell | 2019 |
| 30905542 | Lead optimization and efficacy evaluation of quinazoline-based BET family inhibitors for potential treatment of cancer and inflammatory diseases. | Bioorganic and Medicinal Chemistry Letters | 2019 |
| 31535023 | A novel P300 inhibitor reverses DUX4-mediated global histone H3 hyperacetylation, target gene expression, and cell death. | Science advances | 2019 |
| 29537847 | Insights into the Action of Inhibitor Enantiomers against Histone Lysine Demethylase 5A. | Journal of Medicinal Chemistry | 2018 |
| 30268702 | Discovery and lead identification of quinazoline-based BRD4 inhibitors. | Bioorganic and Medicinal Chemistry Letters | 2018 |
| 30392349 | Structure-Based Engineering of Irreversible Inhibitors against Histone Lysine Demethylase KDM5A. | Journal of Medicinal Chemistry | 2018 |
| 30479275 | Molecular basis for activation of lecithin:cholesterol acyltransferase by a compound that increases HDL cholesterol. | eLife | 2018 |
| 29945974 | High-throughput screening with nucleosome substrate identifies small-molecule inhibitors of the human histone lysine methyltransferase NSD2. | J Biol Chem | 2018 |
| 30472020 | KDM5 Histone Demethylase Activity Links Cellular Transcriptomic Heterogeneity to Therapeutic Resistance. | Cancer Cell | 2018 |
| 30130298 | Inhibition of spinal 15-LOX-1 attenuates TLR4-dependent, nonsteroidal anti-inflammatory drug-unresponsive hyperalgesia in male rats. | Pain | 2018 |
| 30128752 | Identifying hotspots in land use land cover change and the drivers in a semi-arid region of India. | Environmental Monitoring and Assessment | 2018 |
| 30080846 | KDM5 histone demethylases repress immune response via suppression of STING. | PLoS Biol | 2018 |
| 30648156 | Canvass: A Crowd-Sourced, Natural-Product Screening Library for Exploring Biological Space. | ACS Cent Sci | 2018 |
| 29763427 | Correction: A High-Content Assay Enables the Automated Screening and Identification of Small Molecules with Specific ALDH1A1-Inhibitory Activity. | PLoS ONE | 2018 |
| 29444979 | Irreversible inhibition of cytosolic thioredoxin reductase 1 as a mechanistic basis for anticancer therapy. | Science Translational Medicine | 2018 |
| 29309117 | Chemical Control of a CRISPR-Cas9 Acetyltransferase. | ACS Chemical Biology | 2018 |
| 29567993 | Unexplored therapeutic opportunities in the human genome. | Nat Rev Drug Discov | 2018 |
| 29472638 | Unexplored therapeutic opportunities in the human genome. | Nat Rev Drug Discov | 2018 |
| 29146736 | Quantitative high-throughput screening identifies cytoprotective molecules that enhance SUMO conjugation via the inhibition of SUMO-specific protease (SENP)2. | FASEB Journal | 2018 |
| 29800515 | Fragment-Based Discovery of a Regulatory Site in Thioredoxin Glutathione Reductase Acting as "Doorstop" for NADPH Entry. | ACS Chemical Biology | 2018 |
| 29767973 | Discovery of Orally Bioavailable, Quinoline-Based Aldehyde Dehydrogenase 1A1 (ALDH1A1) Inhibitors with Potent Cellular Activity. | J Med Chem | 2018 |
| 28129349 | A High-Content Assay Enables the Automated Screening and Identification of Small Molecules with Specific ALDH1A1-Inhibitory Activity. | PLoS ONE | 2017 |
| 28825467 | Parallel Chemistry Approach to Identify Novel Nuclear Receptor Ligands Based on the GW0742 Scaffold. | ACS Combinatorial Science | 2017 |
| 28775075 | First Selective 12-LOX Inhibitor, ML355, Impairs Thrombus Formation and Vessel Occlusion In Vivo With Minimal Effects on Hemostasis. | Arteriosclerosis, Thrombosis, and Vascular Biology | 2017 |