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Author Details

Douglas D Ross
Greenebaum Comprehensive Cancer Center, University of Maryland
1979
127
50
PMIDPaper TitleJournal TitlePublished Year
33562646Metformin and Androgen Receptor-Axis-Targeted (ARAT) Agents Induce Two PARP-1-Dependent Cell Death Pathways in Androgen-Sensitive Human Prostate Cancer Cells.Cancers (Basel)2021
27286290Methods to Discover Alternative Promoter Usage and Transcriptional Regulation of Murine Bcrp1.J Vis Exp2016
27590344Death-associated Protein Kinase-1 Expression and Autophagy in Chronic Lymphocytic Leukemia Are Dependent on Activating Transcription Factor-6 and CCAAT/Enhancer-binding Protein-β.J Biol Chem2016
25586604Concomitant bone marrow involvement by plasma cell myeloma and primary myelodysplastic syndrome with biclonal complex chromosome anomalies.Leuk Lymphoma2015
25615818Functional cyclic AMP response element in the breast cancer resistance protein (BCRP/ABCG2) promoter modulates epidermal growth factor receptor pathway- or androgen withdrawal-mediated BCRP/ABCG2 transcription in human cancer cells.Biochim Biophys Acta2015
23150485Induction of multidrug resistance transporter ABCG2 by prolactin in human breast cancer cells.Mol Pharmacol2013
24189494Bcrp1 transcription in mouse testis is controlled by a promoter upstream of a novel first exon (E1U) regulated by steroidogenic factor-1.Biochim Biophys Acta2013
23403629Translational phase I trial of vorinostat (suberoylanilide hydroxamic acid) combined with cytarabine and etoposide in patients with relapsed, refractory, or high-risk acute myeloid leukemia.Clin Cancer Res2013
23065516Dasatinib targets chronic myeloid leukemia-CD34+ progenitors as effectively as it targets mature cells.Haematologica2013
22098950Breast cancer resistance protein (BCRP/ABCG2): its role in multidrug resistance and regulation of its gene expression.Chin J Cancer2012
22248732Role of breast cancer resistance protein (BCRP/ABCG2) in cancer drug resistance.Biochem Pharmacol2012
21220496Drug efflux by breast cancer resistance protein is a mechanism of resistance to the benzimidazole insulin-like growth factor receptor/insulin receptor inhibitor, BMS-536924.Mol Cancer Ther2011
21553329Creative solution for implementation of experiential, competency-based palliative care training for internal medicine residents.J Cancer Educ2011
21718815Identification and characterization of the major alternative promoter regulating Bcrp1/Abcg2 expression in the mouse intestine.Biochim Biophys Acta2011
19949928Impact of breast cancer resistance protein on cancer treatment outcomes.Methods Mol Biol2010
20804740A novel xenobiotic responsive element regulated by aryl hydrocarbon receptor is involved in the induction of BCRP/ABCG2 in LS174T cells.Biochem Pharmacol2010
20510678Impact of system L amino acid transporter 1 (LAT1) on proliferation of human ovarian cancer cells: a possible target for combination therapy with anti-proliferative aminopeptidase inhibitors.Biochem Pharmacol2010
20460431Aryl hydrocarbon receptor is a transcriptional activator of the human breast cancer resistance protein (BCRP/ABCG2).Mol Pharmacol2010
20145614Side-population cells in luminal-type breast cancer have tumour-initiating cell properties, and are regulated by HER2 expression and signalling.Br J Cancer2010
20419431Methods to evaluate transporter activity in cancer.Methods Mol Biol2010
19223502Preclinical studies of vorinostat (suberoylanilide hydroxamic acid) combined with cytosine arabinoside and etoposide for treatment of acute leukemias.Clin Cancer Res2009
19509267Suberoylanilide hydroxamic acid (Zolinza/vorinostat) sensitizes TRAIL-resistant breast cancer cells orthotopically implanted in BALB/c nude mice.Mol Cancer Ther2009
18042733Progesterone receptor (PR) isoforms PRA and PRB differentially regulate expression of the breast cancer resistance protein in human placental choriocarcinoma BeWo cells.Mol Pharmacol2008
18186545Experimental design and interaction analysis of combination studies of drugs with log-linear dose responses.Stat Med2008
18056989The 44-kDa Pim-1 kinase phosphorylates BCRP/ABCG2 and thereby promotes its multimerization and drug-resistant activity in human prostate cancer cells.J Biol Chem2008
17187253Flavopiridol synergizes TRAIL cytotoxicity by downregulation of FLIPL.Cancer Chemother Pharmacol2007
17475205Mechanisms of resistance and adaptation to thapsigargin in androgen-independent prostate cancer PC3 and DU145 cells.Arch Biochem Biophys2007
16543472Complex interaction of BCRP/ABCG2 and imatinib in BCR-ABL-expressing cells: BCRP-mediated resistance to imatinib is attenuated by imatinib-induced reduction of BCRP expression.Blood2006
16770788Thapsigargin resistance in human prostate cancer cells.Cancer2006
16707421Novel 5' untranslated region variants of BCRP mRNA are differentially expressed in drug-selected cancer cells and in normal human tissues: implications for drug resistance, tissue-specific expression, and alternative promoter usage.Cancer Res2006
16944951Alterations in the mitochondrial proteome of adriamycin resistant MCF-7 breast cancer cells.J Proteome Res2006
16404634Cyclosporin A, tacrolimus and sirolimus are potent inhibitors of the human breast cancer resistance protein (ABCG2) and reverse resistance to mitoxantrone and topotecan.Cancer Chemother Pharmacol2006
15661261A phase I and pharmacologic study of idarubicin, cytarabine, etoposide, and the multidrug resistance protein (MDR1/Pgp) inhibitor PSC-833 in patients with refractory leukemia.Leuk Res2005
16238509Long-term evaluation of required coursework in palliative and end-of-life care for medical students.J Palliat Med2005
16273296Interactive effects of histone deacetylase inhibitors and TRAIL on apoptosis in human leukemia cells: involvement of both death receptor and mitochondrial pathways.Int J Mol Med2005
16322302Phase I and pharmacokinetic study of flavopiridol followed by 1-beta-D-arabinofuranosylcytosine and mitoxantrone in relapsed and refractory adult acute leukemias.Clin Cancer Res2005
16083366Message for mid-term, 2005.J Cancer Educ2005
15994225The ErbB3-binding protein Ebp1 suppresses androgen receptor-mediated gene transcription and tumorigenesis of prostate cancer cells.Proc Natl Acad Sci U S A2005
16026644Interactive effects of HDAC inhibitors and TRAIL on apoptosis are associated with changes in mitochondrial functions and expressions of cell cycle regulatory genes in multiple myeloma.Neoplasia2005
15580504Plasma pharmacokinetics and tissue distribution of the breast cancer resistance protein (BCRP/ABCG2) inhibitor fumitremorgin C in SCID mice bearing T8 tumors.Cancer Chemother Pharmacol2005
14618629Reversal of breast cancer resistance protein (BCRP/ABCG2)-mediated drug resistance by novobiocin, a coumermycin antibiotic.Int J Cancer2004
15634651Modulation of breast cancer resistance protein (BCRP/ABCG2) gene expression using RNA interference.Mol Cancer Ther2004
15521915Breast cancer resistance protein (BCRP/MXR/ABCG2) in adult acute lymphoblastic leukaemia: frequent expression and possible correlation with shorter disease-free survival.Br J Haematol2004
15623606Phase I clinical trial of the inosine monophosphate dehydrogenase inhibitor mycophenolate mofetil (cellcept) in advanced multiple myeloma patients.Clin Cancer Res2004
15208643Breast cancer resistance protein (BCRP/MXR/ABCG2) in acute myeloid leukemia: discordance between expression and function.Leukemia2004
15203030Liquid chromatography method for the quantitation of the breast cancer resistance protein ABCG2 inhibitor fumitremorgin C and its chemical analogues in mouse plasma and tissues.J Chromatogr B Analyt Technol Biomed Life Sci2004
15494300Modulation of drug resistance transporters as a strategy for treating myelodysplastic syndrome.Best Pract Res Clin Haematol2004
15456662Development of required postgraduate palliative care training for internal medicine residents and medical oncology fellows.J Cancer Educ2004
15324691Mining our ABCs: pharmacogenomic approach for evaluating transporter function in cancer drug resistance.Cancer Cell2004
14973083Identification of a novel estrogen response element in the breast cancer resistance protein (ABCG2) gene.Cancer Res2004
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Collaborators

Mayo Clinic
Co-authored papers 4
University of Toronto
Co-authored papers 2
Research Institute, The Hospital for Sick Children.
Co-authored papers 2
Department of Pharmaceutical and Health Sciences, Western New England University
Co-authored papers 2
Co-authored papers 2
Department of Pharmaceutical Sciences, Utrecht University
Co-authored papers 2
University of Toronto.
Co-authored papers 2
Mayo Clinic
Co-authored papers 1
Co-authored papers 1
Co-authored papers 1
Center for Cancer Research, National Cancer Institute, National Institutes of Health
Co-authored papers 1
Co-authored papers 1
Hospital for Sick Children, University Avenue
Co-authored papers 1
University of British Columbia
Co-authored papers 1
Tohoku Medical and Pharmaceutical University Hospital.
Co-authored papers 1
University of British Columbia
Co-authored papers 1
Georgetown University Medical Center, Georgetown University
Co-authored papers 1
Co-authored papers 1
University of California los angeles
Co-authored papers 1
National Cancer Institute
Co-authored papers 1
University of Toronto
Co-authored papers 1
Co-authored papers 1
Mayo Clinic
Co-authored papers 1
Research Institute, Hospital for Sick Children, University Avenue
Co-authored papers 1
Duke University School of Medicine
Co-authored papers 1
Mayo Clinic
Co-authored papers 1
Institute of Basic Medical Sciences, University of Oslo
Co-authored papers 1
Center for Cancer Research, National Cancer Institute
Co-authored papers 1
University of Maryland, College Park
Co-authored papers 1
Center for Transformative AI and Robotics, Tohoku University
Co-authored papers 1