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Author Details

Svitlana Tyekucheva
Dana-Farber Cancer Institute
2006
60
28
PMIDPaper TitleJournal TitlePublished Year
36287227Pirtobrutinib targets BTK C481S in ibrutinib-resistant CLL but second-site BTK mutations lead to resistance.Blood Adv2023
37885824Cross-Study Replicability in Cluster Analysis.Stat Sci2023
37146250Genetic events associated with venetoclax resistance in CLL identified by whole-exome sequencing of patient samples.Blood2023
37407670A harmonized resource of integrated prostate cancer clinical, -omic, and signature features.Sci Data2023
36717653A phase 1b study of ibrutinib in combination with obinutuzumab in patients with relapsed or refractory chronic lymphocytic leukemia.Leukemia2023
36511902The Prostate Stromal Transcriptome in Aggressive and Lethal Prostate Cancer.Mol Cancer Res2023
36711769curatedPCaData: Integration of clinical, genomic, and signature features in a curated and harmonized prostate cancer data resource.bioRxiv2023
36732326Circulating Th17 T cells at treatment onset predict autoimmune toxicity of PI3Kδ inhibitors.Blood Cancer J2023
36315919Rare Germline <i>ATM</i> Variants Influence the Development of Chronic Lymphocytic Leukemia.J Clin Oncol2023
34743191A T cell inflammatory phenotype is associated with autoimmune toxicity of the PI3K inhibitor duvelisib in chronic lymphocytic leukemia.Leukemia2022
35737367Prognostic and Biologic Significance of ERBB2-Low Expression in Early-Stage Breast Cancer.JAMA Oncol2022
36125434Differences in Prostate Cancer Transcriptomes by Age at Diagnosis: Are Primary Tumors from Older Men Inherently Different?Cancer Prev Res (Phila)2022
35172272Serum thymidine kinase activity in patients with hormone receptor-positive and HER2-negative metastatic breast cancer treated with palbociclib and fulvestrant.Eur J Cancer2022
35170759Idelalisib reduces regulatory T cells and activates T helper 17 cell differentiation in relapsed refractory patients with chronic lymphocytic leukaemia.Br J Haematol2022
34788401Venetoclax plus dose-adjusted R-EPOCH for Richter syndrome.Blood2022
32820271A phase 1b/2 study of duvelisib in combination with FCR (DFCR) for frontline therapy for younger CLL patients.Leukemia2021
33684943Activation of the MAPK pathway mediates resistance to PI3K inhibitors in chronic lymphocytic leukemia.Blood2021
33500320Gene Expression Pathways in Prostate Tissue Associated with Vigorous Physical Activity in Prostate Cancer.Cancer Epidemiol Biomarkers Prev2021
34939926Extent, impact, and mitigation of batch effects in tumor biomarker studies using tissue microarrays.Elife2021
34534514Acalabrutinib, venetoclax, and obinutuzumab as frontline treatment for chronic lymphocytic leukaemia: a single-arm, open-label, phase 2 study.Lancet Oncol2021
34311724Transcriptional landscape of PTEN loss in primary prostate cancer.BMC Cancer2021
33373063Targeting constitutively active STAT3 in chronic lymphocytic leukemia: A clinical trial of the STAT3 inhibitor pyrimethamine with pharmacodynamic analyses.Am J Hematol2021
33168599Metabolomics of Prostate Cancer Gleason Score in Tumor Tissue and Serum.Mol Cancer Res2021
31157686A New Classification of Benign, Premalignant, and Malignant Endometrial Tissues Using Machine Learning Applied to 1413 Candidate Variables.Int J Gynecol Pathol2020
32913135Multiplex Immunofluorescence in Formalin-Fixed Paraffin-Embedded Tumor Tissue to Identify Single-Cell-Level PI3K Pathway Activation.Clin Cancer Res2020
33015524Systematic Assessment of Tumor Purity and Its Clinical Implications.JCO Precis Oncol2020
30333152Genetic and Epigenetic Determinants of Aggressiveness in Cribriform Carcinoma of the Prostate.Mol Cancer Res2019
37736115Modeling genetic heterogeneity of drug response and resistance in cancer.Curr Opin Syst Biol2019
31208944Ibrutinib plus fludarabine, cyclophosphamide, and rituximab as initial treatment for younger patients with chronic lymphocytic leukaemia: a single-arm, multicentre, phase 2 trial.Lancet Haematol2019
30578319Inhibition of de novo lipogenesis targets androgen receptor signaling in castration-resistant prostate cancer.Proc Natl Acad Sci U S A2019
30602500Low Expression of the Androgen-Induced Tumor Suppressor Gene <i>PLZF</i> and Lethal Prostate Cancer.Cancer Epidemiol Biomarkers Prev2019
29141848MYC Overexpression at the Protein and mRNA Level and Cancer Outcomes among Men Treated with Radical Prostatectomy for Prostate Cancer.Cancer Epidemiol Biomarkers Prev2018
30469014Transcriptome Deconvolution of Heterogeneous Tumor Samples with Immune Infiltration.iScience2018
28074002Metabolic Profiling in Formalin-Fixed and Paraffin-Embedded Prostate Cancer Tissues.Mol Cancer Res2017
28700821Gene expression profiling of prostate tissue identifies chromatin regulation as a potential link between obesity and lethal prostate cancer.Cancer2017
28871082Stromal and epithelial transcriptional map of initiation progression and metastatic potential of human prostate cancer.Nat Commun2017
27663590Prognostic Utility of a New mRNA Expression Signature of Gleason Score.Clin Cancer Res2017
27078000Computational Reconstruction of NFκB Pathway Interaction Mechanisms during Prostate Cancer.PLoS Comput Biol2016
26490316Stress-Related Signaling Pathways in Lethal and Nonlethal Prostate Cancer.Clin Cancer Res2016
27980733The role of tumor metabolism as a driver of prostate cancer progression and lethal disease: results from a nested case-control study.Cancer Metab2016
27325648Cholesterol Metabolism and Prostate Cancer Lethality.Cancer Res2016
25371445Association of prostate cancer risk variants with gene expression in normal and tumor tissue.Cancer Epidemiol Biomarkers Prev2015
25870172Molecular differences in transition zone and peripheral zone prostate tumors.Carcinogenesis2015
25937617Comparing Platforms for Messenger RNA Expression Profiling of Archival Formalin-Fixed, Paraffin-Embedded Tissues.J Mol Diagn2015
24497570A novel direct activator of AMPK inhibits prostate cancer growth by blocking lipogenesis.EMBO Mol Med2014
24700801Comparative meta-analysis of prognostic gene signatures for late-stage ovarian cancer.J Natl Cancer Inst2014
24418822De novo fatty acid synthesis at the mitotic exit is required to complete cellular division.Cell Cycle2014
23374354Integrative eQTL-based analyses reveal the biology of breast cancer risk loci.Cell2013
24240475A network of epigenetic regulators guides developmental haematopoiesis in vivo.Nat Cell Biol2013
23550061curatedOvarianData: clinically annotated data for the ovarian cancer transcriptome.Database (Oxford)2013
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Collaborators

Weill Medical College of Cornell University
Co-authored papers 22
Co-authored papers 20
The Prostate Cancer Clinical Trials Consortium
Co-authored papers 14
Co-authored papers 13
Dana Farber Cancer Institute.
Co-authored papers 10
Memorial Sloan Kettering Cancer Center
Co-authored papers 6
Harvard T.H. Chan School of Public Health
Co-authored papers 6
National Cancer Institute
Co-authored papers 5
Brigham and Women's Hospital
Co-authored papers 5
Dana-Farber Cancer Institute
Co-authored papers 4
Co-authored papers 3
Co-authored papers 3
Broad Institute of MIT and Harvard
Co-authored papers 3
City University of New York School of Public Health
Co-authored papers 3
Broad Institute of the Massachusetts Institute of Technology and Harvard
Co-authored papers 3
Co-authored papers 3
University of Colorado Anschutz Medical Campus
Co-authored papers 3
Johns Hopkins University
Co-authored papers 3
Broad Institute of Massachusetts Institute of Technology and Harvard
Co-authored papers 3
Co-authored papers 2
Johns Hopkins University School of Medicine
Co-authored papers 2
T.J. Watson Research Center
Co-authored papers 2
Princess Margaret Cancer Centre, University Health Network
Co-authored papers 2
Johns Hopkins University
Co-authored papers 2
Co-authored papers 2
Novartis Institutes for BioMedical Research
Co-authored papers 2
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Georgetown University
Co-authored papers 2
Dana-Farber Cancer Institute
Co-authored papers 2
The University of Texas MD Anderson Cancer Center
Co-authored papers 2