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Author Details

Michael Hsing
University of British Columbia
2004
32
18
PMIDPaper TitleJournal TitlePublished Year
34332092Drugging the 'undruggable'. Therapeutic targeting of protein-DNA interactions with the use of computer-aided drug discovery methods.Drug Discov Today2021
34681172Deep Modeling of Regulating Effects of Small Molecules on Longevity-Associated Genes.Pharmaceuticals (Basel)2021
30927317ETS transcription factors as emerging drug targets in cancer.Med Res Rev2020
32607441Deep Docking: A Deep Learning Platform for Augmentation of Structure Based Drug Discovery.ACS Cent Sci2020
32162456Rapid Identification of Potential Inhibitors of SARS-CoV-2 Main Protease by Deep Docking of 1.3 Billion Compounds.Mol Inform2020
31504186DeepCOP: deep learning-based approach to predict gene regulating effects of small molecules.Bioinformatics2020
31554191Computer-Aided Discovery of Small Molecule Inhibitors of Thymocyte Selection-Associated High Mobility Group Box Protein (TOX) as Potential Therapeutics for Cutaneous T-Cell Lymphomas.Molecules2019
30063345Toxic Colors: The Use of Deep Learning for Predicting Toxicity of Compounds Merely from Their Graphic Images.J Chem Inf Model2018
28038451Androgen receptor transcriptionally regulates semaphorin 3C in a GATA2-dependent manner.Oncotarget2017
28283588Selectively targeting the DNA-binding domain of the androgen receptor as a prospective therapy for prostate cancer.J Biol Chem2017
28465491Discovery and characterization of small molecules targeting the DNA-binding ETS domain of ERG in prostate cancer.Oncotarget2017
26092939Mitf is a master regulator of the v-ATPase, forming a control module for cellular homeostasis with v-ATPase and TORC1.J Cell Sci2015
26500294Selectively targeting the DNA-binding domain of the androgen receptor as a prospective therapy for prostate cancer.J Biol Chem2015
24478219Prioritizing disease-linked variants, genes, and pathways with an interactive whole-genome analysis pipeline.Hum Mutat2014
25459660Identification of a potent antiandrogen that targets the BF3 site of the androgen receptor and inhibits enzalutamide-resistant prostate cancer.Chem Biol2014
25455729Orphan nuclear receptors as drug targets for the treatment of prostate and breast cancers.Cancer Treat Rev2014
25086042Selectively targeting the DNA-binding domain of the androgen receptor as a prospective therapy for prostate cancer.J Biol Chem2014
23990327The mycobacterial antibiotic resistance determinant WhiB7 acts as a transcriptional activator by binding the primary sigma factor SigA (RpoV).Nucleic Acids Res2013
22158708Polycomb repressive complex 2 regulates normal development of the mouse heart.Circ Res2012
22730434gSearch: a fast and flexible general search tool for whole-genome sequencing.Bioinformatics2012
22323072Taxonomizing, sizing, and overcoming the incidentalome.Genet Med2012
22066782Cheminformatics-driven discovery of selective, nanomolar inhibitors for staphylococcal pyruvate kinase.ACS Chem Biol2012
21183585CompleteMOTIFs: DNA motif discovery platform for transcription factor binding experiments.Bioinformatics2011
21357306Identification of pyruvate kinase in methicillin-resistant Staphylococcus aureus as a novel antimicrobial drug target.Antimicrob Agents Chemother2011
21166474Mapping the protein interaction network in methicillin-resistant Staphylococcus aureus.J Proteome Res2011
19193143The effect of insertions and deletions on wirings in protein-protein interaction networks: a large-scale study.J Comput Biol2009
20198194Predicting highly-connected hubs in protein interaction networks by QSAR and biological data descriptors.Bioinformation2009
18578882Indel PDB: a database of structural insertions and deletions derived from sequence alignments of closely related proteins.BMC Bioinformatics2008
18796161The use of Gene Ontology terms for predicting highly-connected 'hub' nodes in protein-protein interaction networks.BMC Syst Biol2008
17598914Relationship between insertion/deletion (indel) frequency of proteins and essentiality.BMC Bioinformatics2007
15494071Modeling of cell signaling pathways in macrophages by semantic networks.BMC Bioinformatics2004
15189571Interaction profile-based protein classification of death domain.BMC Bioinformatics2004
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Collaborators

Sek Won Kong
Boston Children's Hospital, Seoul National University, Seoul National University Hospital
Co-authored papers 6
Martin E Gleave
University of British Columbia
Co-authored papers 3
Kyungjoon Lee
Hanyang University Hospital
Co-authored papers 3
Fereydoun Hormozdiari
University of California davis
Co-authored papers 2
Aibin He
College of Plant Science and Technology, Huazhong Agricultural University
Co-authored papers 2
Suleyman Cenk Sahinalp
National Cancer Institute, National Institutes of Health
Co-authored papers 2
Justin Bohn
Harvard Medical School and Harvard Pilgrim Health Care Institute
Co-authored papers 2
Natalie C J Strynadka
The University of British Columbia
Co-authored papers 2
William T Pu
Boston Children's Hospital, Harvard Medical School
Co-authored papers 2
Kyu-Baek Hwang
Soongsil University
Co-authored papers 2
Isaac S Kohane
Harvard Medical School
Co-authored papers 2
Yuzhuo Wang
University of British Columbia
Co-authored papers 2
Arnar Palsson
Institute of Life and Environmental Sciences, University of Iceland
Co-authored papers 1
Patrick Cahan
Johns Hopkins University
Co-authored papers 1
Francesca Pignoni
Upstate Medical University
Co-authored papers 1
Farhad Hormozdiari
Co-authored papers 1
Robert Siddaway
Hospital for Sick Children
Co-authored papers 1
Christine E Seidman
Brigham and Women's Hospital (Y.K.
Co-authored papers 1
Tianyi Zhang
National Institute on Aging, National Institutes of Health
Co-authored papers 1
Taemin Song
Soongsil University
Co-authored papers 1
Margret H Ogmundsdottir
Biomedical Center, University of Iceland
Co-authored papers 1
Lakshmi Kuttippurathu
Co-authored papers 1
Colin R Goding
Ludwig Institute for Cancer Research, University of Oxford
Co-authored papers 1
In-Hee Lee
Co-authored papers 1
Robert C Green
Brigham and Women's Hospital, Broad Institute Ariadne Labs and Harvard Medical School
Co-authored papers 1
Amina Zoubeidi
University of British Columbia
Co-authored papers 1
Danos C Christodoulou
University of Patras
Co-authored papers 1
Huafeng Xie
South China University of Technology
Co-authored papers 1
Alexander von Gise
Hannover Medical School
Co-authored papers 1
Stuart H Orkin
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Release 1.2