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Author Details

Wells A Messersmith
University of Colorado Anschutz Medical Campus
1995
195
57
PMIDPaper TitleJournal TitlePublished Year
36602514Improved Survival After Adjuvant Therapy in Locally Advanced Rectal Cancer Patients With Pathologic Complete Response.Dis Colon Rectum2023
37772994Pancreatic Ductal Adenocarcinoma Cells Regulate NLRP3 Activation to Generate a Tolerogenic Microenvironment.Cancer Res Commun2023
37391327Pulmonary metastasectomy is associated with survival after lung-only recurrence in pancreatic cancer.Surgery2023
37379764Avelumab or talazoparib in combination with binimetinib in metastatic pancreatic ductal adenocarcinoma: dose-finding results from phase Ib of the JAVELIN PARP MEKi trial.ESMO Open2023
37309603Correction: Phase I Dose-Escalation Trial of MIW815 (ADU-S100), an Intratumoral STING Agonist, in Patients with Advanced/Metastatic Solid Tumors or Lymphomas.Clin Cancer Res2023
37308125Anal Carcinoma, Version 2.2023, NCCN Clinical Practice Guidelines in Oncology.J Natl Compr Canc Netw2023
34716197Phase I Dose-Escalation Trial of MIW815 (ADU-S100), an Intratumoral STING Agonist, in Patients with Advanced/Metastatic Solid Tumors or Lymphomas.Clin Cancer Res2022
36970055A Preclinical and Phase Ib Study of Palbociclib plus Nab-Paclitaxel in Patients with Metastatic Adenocarcinoma of the Pancreas.Cancer Res Commun2022
36969746A Phase II Study Investigating Cabozantinib in Patients with Refractory Metastatic Colorectal Cancer (AGICC 17CRC01).Cancer Res Commun2022
36419897Cabozantinib sensitizes microsatellite stable colorectal cancer to immune checkpoint blockade by immune modulation in human immune system mouse models.Front Oncol2022
36309653ATM kinase inhibitor AZD0156 in combination with irinotecan and 5-fluorouracil in preclinical models of colorectal cancer.BMC Cancer2022
36240850Rectal Cancer, Version 2.2022, NCCN Clinical Practice Guidelines in Oncology.J Natl Compr Canc Netw2022
36240469Tissue Displacement Versus Two Primary Colorectal Carcinomas? A Case Report on the Utility of Comparative Sequencing.JCO Precis Oncol2022
35192363Design, Synthesis, and Biological Evaluation of the First Inhibitors of Oncogenic CHD1L.J Med Chem2022
35288468Exploring the safety, effect on the tumor microenvironment, and efficacy of itacitinib in combination with epacadostat or parsaclisib in advanced solid tumors: a phase I study.J Immunother Cancer2022
34862244Targeting Treg-Expressed STAT3 Enhances NK-Mediated Surveillance of Metastasis and Improves Therapeutic Response in Pancreatic Adenocarcinoma.Clin Cancer Res2022
32997608Benchmarks for Academic Oncology Faculty.JCO Oncol Pract2021
33854497Testing Cancer Immunotherapy in a Human Immune System Mouse Model: Correlating Treatment Responses to Human Chimerism, Therapeutic Variables and Immune Cell Phenotypes.Front Immunol2021
33742123Isolating and targeting the real-time plasticity and malignant properties of epithelial-mesenchymal transition in cancer.Oncogene2021
33741442Sacituzumab govitecan, a Trop-2-directed antibody-drug conjugate, for patients with epithelial cancer: final safety and efficacy results from the phase I/II IMMU-132-01 basket trial.Ann Oncol2021
33850005Innate Immune Checkpoint Inhibitors: The Next Breakthrough in Medical Oncology?Mol Cancer Ther2021
33869031WEE1 Inhibition in Combination With Targeted Agents and Standard Chemotherapy in Preclinical Models of Pancreatic Ductal Adenocarcinoma.Front Oncol2021
33777751Impact of Radiation Dose on Postoperative Complications in Esophageal and Gastroesophageal Junction Cancers.Front Oncol2021
33724754Colon Cancer, Version 2.2021, NCCN Clinical Practice Guidelines in Oncology.J Natl Compr Canc Netw2021
33526513Induction of ADAM10 by Radiation Therapy Drives Fibrosis, Resistance, and Epithelial-to-Mesenchyal Transition in Pancreatic Cancer.Cancer Res2021
34793719Evorpacept alone and in combination with pembrolizumab or trastuzumab in patients with advanced solid tumours (ASPEN-01): a first-in-human, open-label, multicentre, phase 1 dose-escalation and dose-expansion study.Lancet Oncol2021
34790407Neoadjuvant treatment of localized pancreatic adenocarcinoma.J Gastrointest Oncol2021
34541862Transarterial Radioembolization in Patients With Unresectable Colorectal Cancer Liver Metastases.J Clin Oncol2021
34155509Outcome of neoadjuvant treatment for pancreatic cancer in elderly patients: comparative, observational cohort study.Br J Surg2021
33277184Impact of neoadjuvant chemotherapy and stereotactic body radiation therapy (SBRT) on R0 resection rate for borderline resectable and locally advanced pancreatic cancer.HPB (Oxford)2021
33097963Response to radiotherapy in pancreatic ductal adenocarcinoma is enhanced by inhibition of myeloid-derived suppressor cells using STAT3 anti-sense oligonucleotide.Cancer Immunol Immunother2021
31338636A phase 1b dose escalation study of Wnt pathway inhibitor vantictumab in combination with nab-paclitaxel and gemcitabine in patients with previously untreated metastatic pancreatic cancer.Invest New Drugs2020
32634771NCCN Guidelines Insights: Rectal Cancer, Version 6.2020.J Natl Compr Canc Netw2020
32816368Bitter melon juice intake with gemcitabine intervention circumvents resistance to gemcitabine in pancreatic patient-derived xenograft tumors.Mol Carcinog2020
32694153Phase Ib Study of Wnt Inhibitor Ipafricept with Gemcitabine and nab-paclitaxel in Patients with Previously Untreated Stage IV Pancreatic Cancer.Clin Cancer Res2020
32219196Safety and Pharmacokinetics of CXCR4 Peptide Antagonist, LY2510924, in Combination with Durvalumab in Advanced Refractory Solid Tumors.J Pancreat Cancer2020
32414750Preclinical and Dose-Finding Phase I Trial Results of Combined Treatment with a TORC1/2 Inhibitor (TAK-228) and Aurora A Kinase Inhibitor (Alisertib) in Solid Tumors.Clin Cancer Res2020
32499299First-in-Class Inhibitors of Oncogenic CHD1L with Preclinical Activity against Colorectal Cancer.Mol Cancer Ther2020
32204315Wee1 Inhibition Enhances the Anti-Tumor Effects of Capecitabine in Preclinical Models of Triple-Negative Breast Cancer.Cancers (Basel)2020
31513709Development of an Adrenocortical Cancer Humanized Mouse Model to Characterize Anti-PD1 Effects on Tumor Microenvironment.J Clin Endocrinol Metab2020
30944125Pancreatic Tumor Microenvironment Modulation by EphB4-ephrinB2 Inhibition and Radiation Combination.Clin Cancer Res2019
31675229Drug Design Targeting T-Cell Factor-Driven Epithelial-Mesenchymal Transition as a Therapeutic Strategy for Colorectal Cancer.J Med Chem2019
31398063Sacituzumab govitecan: breakthrough targeted therapy for triple-negative breast cancer.Expert Rev Anticancer Ther2019
30736857Characterization of immune responses to anti-PD-1 mono and combination immunotherapy in hematopoietic humanized mice implanted with tumor xenografts.J Immunother Cancer2019
31117039NCCN Guidelines Updates: Management of Metastatic Colorectal Cancer.J Natl Compr Canc Netw2019
28887726Long-Term Follow-Up of Desmoid Fibromatosis Treated with PF-03084014, an Oral Gamma Secretase Inhibitor.Ann Surg Oncol2018
30026382Cabozantinib Exhibits Potent Antitumor Activity in Colorectal Cancer Patient-Derived Tumor Xenograft Models via Autophagy and Signaling Mechanisms.Mol Cancer Ther2018
30048249Dual compartmental targeting of cell cycle and angiogenic kinases in colorectal cancer models.Anticancer Drugs2018
30042150Phase Ib Results of the Rational Combination of Selumetinib and Cyclosporin A in Advanced Solid Tumors with an Expansion Cohort in Metastatic Colorectal Cancer.Cancer Res2018
30139840A Phase I Dose-Escalation Study of Linsitinib (OSI-906), a Small-Molecule Dual Insulin-Like Growth Factor-1 Receptor/Insulin Receptor Kinase Inhibitor, in Combination with Irinotecan in Patients with Advanced Cancer.Oncologist2018
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Collaborators

University of Colorado School of Medicine
Co-authored papers 41
Huntsman Cancer Institute, The University of Utah
Co-authored papers 29
Ohio State University
Co-authored papers 13
Northwestern University Feinberg School of Medicine
Co-authored papers 11
University of Colorado School of Medicine
Co-authored papers 10
Johns Hopkins School of Medicine
Co-authored papers 9
Rogel Cancer Center, University of Michigan ann arbor
Co-authored papers 8
University of Colorado School of Medicine
Co-authored papers 8
Mount Sinai Hospital
Co-authored papers 8
University of Colorado
Co-authored papers 6
University of Colorado Anschutz Medical Campus
Co-authored papers 6
Brody School of Medicine, East Carolina University
Co-authored papers 6
University of Colorado Anschutz Medical Campus
Co-authored papers 5
Sidney Kimmel Cancer Center at Thomas Jefferson University
Co-authored papers 5
Weill Cornell Medical College
Co-authored papers 5
University of Colorado School of Medicine
Co-authored papers 5
University of Colorado
Co-authored papers 5
Co-authored papers 4
University of Colorado
Co-authored papers 4
The University of Texas MD Anderson Cancer Center
Co-authored papers 4
Massachusetts General Hospital Cancer Center
Co-authored papers 4
University of Colorado Anschutz Medical Campus
Co-authored papers 4
University of Colorado Denver
Co-authored papers 4
University of Colorado Denver at Anschutz Medical Campus
Co-authored papers 4
University of Colorado Anschutz Medical Campus
Co-authored papers 3
University of Colorado Denver at Anschutz Medical Campus
Co-authored papers 3
Dartmouth Cancer Center
Co-authored papers 3
Universite de Sherbrooke
Co-authored papers 3
University of Colorado Denver
Co-authored papers 3
University of Texas MD Anderson Cancer Center
Co-authored papers 3