Skip to Main Content

Author Details

Kenneth D Westover
University of Texas Southwestern Medical Center
1998
104
38
PMIDPaper TitleJournal TitlePublished Year
36826833Development of a Covalent Inhibitor of c-Jun N-Terminal Protein Kinase (JNK) 2/3 with Selectivity over JNK1.J Med Chem2023
37792675Dynamic ultrasound molecular-targeted imaging of senescence in evaluation of lapatinib resistance in HER2-positive breast cancer.Cancer Med2023
37721853GLUT3 promotes macrophage signaling and function via RAS-mediated endocytosis in atopic dermatitis and wound healing.J Clin Invest2023
34547468PD-L1<sup>P146R</sup> is prognostic and a negative predictor of response to immunotherapy in gastric cancer.Mol Ther2022
35806100Thermal Shift Assay for Small GTPase Stability Screening: Evaluation and Suitability.Int J Mol Sci2022
35830884NCCN Guidelines® Insights: Lung Cancer Screening, Version 1.2022.J Natl Compr Canc Netw2022
35597007Synthesis and Structure-Activity relationships of cyclin-dependent kinase 11 inhibitors based on a diaminothiazole scaffold.Eur J Med Chem2022
35595166Therapeutic Targeting the Allosteric Cysteinome of RAS and Kinase Families.J Mol Biol2022
36148376T Stage and Pretreatment Standardized Uptake Values Predict Tumor Recurrence With 5-Fraction SABR in Early-Stage Non-Small Cell Lung Cancer.Adv Radiat Oncol2022
36091134Case Report: Resolution of radiation pneumonitis with androgens and growth hormone.Front Oncol2022
35232997ADAP1 promotes latent HIV-1 reactivation by selectively tuning KRAS-ERK-AP-1 T cell signaling-transcriptional axis.Nat Commun2022
34962124Acid-Catalyzed Synthesis of Isatoic Anhydride-8-Secondary Amides Enables IASA Transformations for Medicinal Chemistry.J Org Chem2022
33465697Loss of wild type KRAS in KRAS<sup>MUT</sup> lung adenocarcinoma is associated with cancer mortality and confers sensitivity to FASN inhibitors.Lung Cancer2021
34383006Accelerated Hypofractionated Image-Guided vs Conventional Radiotherapy for Patients With Stage II/III Non-Small Cell Lung Cancer and Poor Performance Status: A Randomized Clinical Trial.JAMA Oncol2021
34625747A structural model of a Ras-Raf signalosome.Nat Struct Mol Biol2021
34159321Rapid assessment of DCLK1 inhibitors using a peptide substrate mobility shift assay.STAR Protoc2021
34077419The nonreceptor tyrosine kinase SRMS inhibits autophagy and promotes tumor growth by phosphorylating the scaffolding protein FKBP51.PLoS Biol2021
34301758Lentiviral-Driven Discovery of Cancer Drug Resistance Mutations.Cancer Res2021
34210327Inhibiting the redox function of APE1 suppresses cervical cancer metastasis via disengagement of ZEB1 from E-cadherin in EMT.J Exp Clin Cancer Res2021
34087169The to and fro of Rho.Structure2021
33972932Contact Tracing in Healthcare Settings During the COVID-19 Pandemic Using Bluetooth Low Energy and Artificial Intelligence-A Viewpoint.Front Artif Intell2021
32509799Structure and Characterization of a Covalent Inhibitor of Src Kinase.Front Mol Biosci2020
34589966Thirteen-Year Survival in a Patient With Diffuse Bilateral Lepidic-Predominant Adenocarcinoma: A Case Report of Lung Transplantation and Local Salvage.JTO Clin Res Rep2020
31935084Structure-Based Design of a Potent and Selective Covalent Inhibitor for SRC Kinase That Targets a P-Loop Cysteine.J Med Chem2020
32048471Dynamic surveillance of tamoxifen-resistance in ER-positive breast cancer by CAIX-targeted ultrasound imaging.Cancer Med2020
31914413A highly selective inhibitor of interleukin-1 receptor-associated kinases 1/4 (IRAK-1/4) delineates the distinct signaling roles of IRAK-1/4 and the TAK1 kinase.J Biol Chem2020
31883964Exploring Targeted Degradation Strategy for Oncogenic KRAS<sup>G12C</sup>.Cell Chem Biol2020
32605999KRAS<sup>Q61H</sup> Preferentially Signals through MAPK in a RAF Dimer-Dependent Manner in Non-Small Cell Lung Cancer.Cancer Res2020
32622875Small molecule inhibition of non-canonical (TAK1-mediated) BMP signaling results in reduced chondrogenic ossification and heterotopic ossification in a rat model of blast-associated combat-related lower limb trauma.Bone2020
32790356Correction to "Synthesis and Structure-Activity Relationships of DCLK1 Kinase Inhibitors Based on a 5,11-Dihydro-6<i>H</i>-benzo[<i>e</i>]pyrimido[5,4-<i>b</i>][1,4]diazepin-6-one Scaffold".J Med Chem2020
32755567Chemical Biology Toolkit for DCLK1 Reveals Connection to RNA Processing.Cell Chem Biol2020
32187889GTP hydrolysis is modulated by Arg34 in the RASopathy-associated KRAS<sup>P34R</sup>.Birth Defects Res2020
32530623Synthesis and Structure-Activity Relationships of DCLK1 Kinase Inhibitors Based on a 5,11-Dihydro-6<i>H</i>-benzo[<i>e</i>]pyrimido[5,4-<i>b</i>][1,4]diazepin-6-one Scaffold.J Med Chem2020
32323324Development of a real-time indoor location system using bluetooth low energy technology and deep learning to facilitate clinical applications.Med Phys2020
32347302Phase II trial of hippocampal-sparing whole brain irradiation with simultaneous integrated boost for metastatic cancer.Neuro Oncol2020
30508618Automated Text Message Reminders Improve Radiation Therapy Compliance.Int J Radiat Oncol Biol Phys2019
31889052Publisher Correction: Green Synthesis of Substituted Anilines and Quinazolines from Isatoic Anhydride-8-amide.Sci Rep2019
31324602Intergrated analysis of ELMO1, serves as a link between tumour mutation burden and epithelial-mesenchymal transition in hepatocellular carcinoma.EBioMedicine2019
31582788Green Synthesis of Substituted Anilines and Quinazolines from Isatoic Anhydride-8-amide.Sci Rep2019
31341022Structural basis of the atypical activation mechanism of KRAS<sup>V14I</sup>.J Biol Chem2019
30987652Restoration of mutant K-Ras repressed miR-199b inhibits K-Ras mutant non-small cell lung cancer progression.J Exp Clin Cancer Res2019
30952657Tissue-Specific Oncogenic Activity of KRAS<sup>A146T</sup>.Cancer Discov2019
30982749Leveraging Compound Promiscuity to Identify Targetable Cysteines within the Kinome.Cell Chem Biol2019
30905681Development of a Selective CDK7 Covalent Inhibitor Reveals Predominant Cell-Cycle Phenotype.Cell Chem Biol2019
30786091Coordinating Tissue Regeneration Through Transforming Growth Factor-β Activated Kinase 1 Inactivation and Reactivation.Stem Cells2019
29235861KRAS Switch Mutants D33E and A59G Crystallize in the State 1 Conformation.Biochemistry2018
30266009A pilot study using kernelled support tensor machine for distant failure prediction in lung SBRT.Med Image Anal2018
30307999Accurate real time localization tracking in a clinical environment using Bluetooth Low Energy and deep learning.PLoS One2018
29616661Shell feature: a new radiomics descriptor for predicting distant failure after radiotherapy in non-small cell lung cancer and cervix cancer.Phys Med Biol2018
29743554GADD45α sensitizes cervical cancer cells to radiotherapy via increasing cytoplasmic APE1 level.Cell Death Dis2018
  • 1 - 50 of 104

Recommended Authors

Nehme El-Hachem
Centre Hospitalier Universitaire Sainte-Justine Research Centre
Career Start Year 2011
Number of shared co-authors 0
Dylan Nelson
Oregon State University
Career Start Year 2011
Number of shared co-authors 4
Saurabh Mendiratta
University of Texas Southwestern Medical Center
Career Start Year 2009
Number of shared co-authors 5
Chen Hu
Johns Hopkins University School of Medicine
Career Start Year 2009
Number of shared co-authors 4
John T Poirier
Laura and Isaac Perlmutter Cancer Center
Career Start Year 2007
Number of shared co-authors 3
Ahmed Aman
Ontario Institute for Cancer Research, University Avenue
Career Start Year 2007
Number of shared co-authors 0
John F Reilly
Goldfinch Bio Inc.
Career Start Year 2007
Number of shared co-authors 3
Jaclyn LoPiccolo
Dana-Farber Cancer Institute
Career Start Year 2007
Number of shared co-authors 1
Jordi Rodon
The University of Texas MD Anderson Cancer Center
Career Start Year 2006
Number of shared co-authors 2
James R Whittle
Walter and Eliza Hall Institute of Medical Research
Career Start Year 2006
Number of shared co-authors 0
Kris C Wood
Duke University
Career Start Year 2005
Number of shared co-authors 1
Luke L Lairson
The Scripps Research Institute
Career Start Year 2003
Number of shared co-authors 0
Trever G Bivona
University of California san francisco
Career Start Year 2002
Number of shared co-authors 4
Craig J Thomas
Center for Cancer Research, National Cancer Institute
Career Start Year 2001
Number of shared co-authors 2
Pingfu Fu
Case Western Reserve University
Career Start Year 2000
Number of shared co-authors 0
Christopher D Willey
University of Alabama at Birmingham
Career Start Year 2000
Number of shared co-authors 2
Chun-Liang Chen
National Dong Hwa University
Career Start Year 1997
Number of shared co-authors 0
Nam Bui
Stanford University
Career Start Year 1996
Number of shared co-authors 0
John D Gordan
Quantitative Biosciences Institute (QBI), University of California San Francisco
Career Start Year 1996
Number of shared co-authors 0
Jorge Nieva
Norris Comprehensive Cancer Center, University of Southern California
Career Start Year 1995
Number of shared co-authors 0
Krister Wennerberg
University of Copenhagen
Career Start Year 1994
Number of shared co-authors 3
Guangrong Qin
Institute for Systems Biology
Career Start Year 1993
Number of shared co-authors 0
Charles M Rudin
Memorial Sloan Kettering Cancer Center
Career Start Year 1989
Number of shared co-authors 3
E Alejandro Sweet-Cordero
University of California San Francisco
Career Start Year 1989
Number of shared co-authors 1
Sun Young Kim
Asan Medical Center, University of Ulsan College of Medicine
Career Start Year 1988
Number of shared co-authors 0
Kevan M Shokat
University of California San Francisco
Career Start Year 1987
Number of shared co-authors 7
Charles L Sawyers
Memorial Sloan Kettering Cancer Center
Career Start Year 1986
Number of shared co-authors 5
Stuart L Schreiber
Broad Institute
Career Start Year 1985
Number of shared co-authors 8
Frank McCormick
Frederick National Laboratory for Cancer Research
Career Start Year 1975
Number of shared co-authors 2
Antonio Jimeno
University of Colorado School of Medicine
Career Start Year 1974
Number of shared co-authors 0

Collaborators

Nathanael S Gray
Harvard Medical School
Co-authored papers 27
Puneeth Iyengar
UT Southwestern Medical Center, Center for Human Nutrition
Co-authored papers 12
Pasi A J??nne
Dana-Farber Cancer Institute
Co-authored papers 10
David A Bushnell
Stanford University
Co-authored papers 7
Peter K Sorger
Co-authored papers 7
Roger D Kornberg
Stanford University
Co-authored papers 7
Chul Ahn
University of Texas Southwestern Medical Center
Co-authored papers 4
David M Sabatini
Whitehead Institute for Biomedical Research and Massachusetts Institute of Technology
Co-authored papers 4
John D Minna
University of Texas Southwestern Medical Center at Dallas
Co-authored papers 3
Jianwei Che
Dana-Farber Cancer Institute
Co-authored papers 3
Michael Levitt
Stanford University
Co-authored papers 2
Alexander Tropsha
Co-authored papers 2
Michael B Westover
Beth Israel Deaconess Medical Center
Co-authored papers 2
Thomas W Gero
Dana-Farber Cancer Institute
Co-authored papers 2
Caitlin E Mills
Co-authored papers 2
Min Shen
National Center for Advancing Translational Sciences, National Institutes of Health
Co-authored papers 2
Ralph E Davis
Stanford University School of Medicine
Co-authored papers 2
Matthew B Boxer
Co-authored papers 2
Senthil K Muthuswamy
Center for Cancer Research, National Cancer Institute, National Institutes of Health
Co-authored papers 2
Yan Liu
Chengdu Medical College
Co-authored papers 2
Douglas A Lauffenburger
Massachusetts Institute of Technology
Co-authored papers 2
Mario Niepel
Co-authored papers 2
Dong Wang
Co-authored papers 2
Matthew Meyerson
Broad Institute
Co-authored papers 1
Benjamin S Braun
Benioff Children's Hospitals, University of California san francisco
Co-authored papers 1
Emily C Tjon
Co-authored papers 1
Can Kayatekin
Co-authored papers 1
Sean Crosson
Co-authored papers 1
Merc?? Crosas
Institute for Quantitative Social Science, Harvard University
Co-authored papers 1
Shannon K McWeeney
Oregon Health & Science University, University of California Berkeley
Co-authored papers 1
Release 1.2