Author details

Full Name

David J Adams

Affiliation

Wellcome Sanger Institute

ORCID

Career Start Year

1980

Papers

379

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
36219477	Mutually exclusive genetic interactions and gene essentiality shape the genomic landscape of primary melanoma.	J Pathol	2023
37635261	Cross-species oncogenomics offers insight into human muscle-invasive bladder cancer.	Genome Biol	2023
37957154	Knockout or inhibition of USP30 protects dopaminergic neurons in a Parkinson's disease mouse model.	Nat Commun	2023
37550943	Breathing in danger: how particulate matter pollution is putting the public at risk of lung cancer<sup>â¿ </sup>.	J Pathol	2023
38057330	Saturation genome editing of DDX3X clarifies pathogenicity of germline and somatic variation.	Nat Commun	2023
37394429	An Atlas of Variant Effects to understand the genome at nucleotide resolution.	Genome Biol	2023
37256941	FIRRM/C1orf112 mediates resolution of homologous recombination intermediates in response to DNA interstrand crosslinks.	Sci Adv	2023
37373578	The Promise of Single-Cell RNA Sequencing to Redefine the Understanding of Crohn's Disease Fibrosis Mechanisms.	J Clin Med	2023
37395714	Acetaldehyde and defective mismatch repair increase colonic tumours in a Lynch syndrome model with Aldh1b1 inactivation.	Dis Model Mech	2023
36890003	Targeting synthetic lethal paralogs in cancer.	Trends Cancer	2023
36876055	Association of germline variants in telomere maintenance genes (<i>POT1, TERF2IP, ACD,</i> and <i>TERT</i>) with spitzoid morphology in familial melanoma: A multi-center case series.	JAAD Int	2023
36539277	Population-based analysis of <i>POT1</i> variants in a cutaneous melanoma case-control cohort.	J Med Genet	2023
36711784	IFI207, a young and fast-evolving antiviral factor, stabilizes STING.	bioRxiv	2023
36637239	Prolidase Deficiency Causes Spontaneous T Cell Activation and Lupus-like Autoimmunity.	J Immunol	2023
36793076	Towards a clinically-based common coordinate framework for the human gut cell atlas: the gut models.	BMC Med Inform Decis Mak	2023
36259947	Identifying the Transcriptional Drivers of Metastasis Embedded within Localized Melanoma.	Cancer Discov	2023
34197659	Molecular pathology of skin adnexal tumours.	Histopathology	2022
35581257	Author Correction: Tumour gene expression signature in primary melanoma predicts long-term outcomes.	Nat Commun	2022
35764636	SHLD1 is dispensable for 53BP1-dependent V(D)J recombination but critical for productive class switch recombination.	Nat Commun	2022
35365791	Identification of gut microbial species linked with disease variability in a widely used mouse model of colitis.	Nat Microbiol	2022
35460607	Germline MBD4 deficiency causes a multi-tumor predisposition syndrome.	Am J Hum Genet	2022
35394069	'Know thyself' - host factors influencing cancer response to immune checkpoint inhibitors.	J Pathol	2022
35357426	Defining novel causal SNPs and linked phenotypes at melanoma-associated loci.	Hum Mol Genet	2022
36292683	Robust Genetic Analysis of the X-Linked Anophthalmic (<i>Ie</i>) Mouse.	Genes (Basel)	2022
36388765	Uncovering novel mutational signatures by <i>de novo</i> extraction with SigProfilerExtractor.	Cell Genom	2022
36112789	Transposon Mutagenesis Reveals RBMS3 Silencing as a Promoter of Malignant Progression of BRAFV600E-Driven Lung Tumorigenesis.	Cancer Res	2022
35073853	The MITRE trial protocol: a study to evaluate the microbiome as a biomarker of efficacy and toxicity in cancer patients receiving immune checkpoint inhibitor therapy.	BMC Cancer	2022
35051265	CRLF3 plays a key role in the final stage of platelet genesis and is a potential therapeutic target for thrombocythemia.	Blood	2022
35296311	Identification and characterisation of spontaneous mutations causing deafness from a targeted knockout programme.	BMC Biol	2022
34958502	Primary de-differentiated, trans-differentiated and undifferentiated melanomas: overview of the clinicopathological, immunohistochemical and molecular spectrum.	Histopathology	2022
35322020	eIF6 rebinding dynamically couples ribosome maturation and translation.	Nat Commun	2022
34791067	Variant Library Annotation Tool (VaLiAnT): an oligonucleotide library design and annotation tool for saturation genome editing and other deep mutational scanning experiments.	Bioinformatics	2022
32330367	Acral lentiginous melanoma: Basic facts, biological characteristics and research perspectives of an understudied disease.	Pigment Cell Melanoma Res	2021
33602918	Tumour gene expression signature in primary melanoma predicts long-term outcomes.	Nat Commun	2021
33545064	Melanoma models for the next generation of therapies.	Cancer Cell	2021
33597266	Epitope spreading toward wild-type melanocyte-lineage antigens rescues suboptimal immune checkpoint blockade responses.	Sci Transl Med	2021
33764464	Mutagenic mechanisms of cancer-associated DNA polymerase Ïµ alleles.	Nucleic Acids Res	2021
33761966	Unraveling the cartography of the cancer ecosystem.	Genome Biol	2021
33758365	CRISPR activation screen in mice identifies novel membrane proteins enhancing pulmonary metastatic colonisation.	Commun Biol	2021
33731925	Identification of bacteria-derived HLA-bound peptides in melanoma.	Nature	2021
33637726	Combinatorial CRISPR screen identifies fitness effects of gene paralogues.	Nat Commun	2021
33500573	Cancer research needs a better map.	Nature	2021
33931647	Cut-like homeobox 1 (CUX1) tumor suppressor gene haploinsufficiency induces apoptosis evasion to sustain myeloid leukemia.	Nat Commun	2021
33722351	Editorial overview: The most difficult of years in cancer research.	Curr Opin Genet Dev	2021
34529939	Cooperation between melanoma cell states promotes metastasis through heterotypic cluster formation.	Dev Cell	2021
34529928	Comprehensive prediction of robust synthetic lethality between paralog pairs in cancer cell lines.	Cell Syst	2021
34543445	Ethanol-induced formation of colorectal tumours and precursors in a mouse model of Lynch syndrome.	J Pathol	2021
34651586	Combined presentation and immunogenicity analysis reveals a recurrent RAS.Q61K neoantigen in melanoma.	J Clin Invest	2021
33963380	Membrane protein regulators of melanoma pulmonary colonization identified using a CRISPRa screen and spontaneous metastasis assay in mice.	G3 (Bethesda)	2021
34155350	The clinicopathologic spectrum and genomic landscape of de-/trans-differentiated melanoma.	Mod Pathol	2021

1 - 50 of 379

Tuo Zhang

Weill Cornell Medical College.

Career Start Year 2013

Number of shared co-authors 1

Christopher A Bristow

The University of Texas MD Anderson Cancer Center

Career Start Year 2005

Number of shared co-authors 14

Jianmin Wang

Roswell Park Comprehensive Cancer Center

Career Start Year 2003

Number of shared co-authors 1

Monte M Winslow

Stanford University School of Medicine

Career Start Year 2002

Number of shared co-authors 3

Michael Slifker

Fox Chase Cancer Center

Career Start Year 2002

Number of shared co-authors 0

Sophia Derdak

Medical University of Vienna

Career Start Year 2001

Number of shared co-authors 29

Kevin R Brown

College Street, University of Toronto

Career Start Year 2000

Number of shared co-authors 11

Celine Lefebvre

The Scripps Research Institute

Career Start Year 1999

Number of shared co-authors 4

Jan Koster

Amsterdam University Medical Centers location AMC

Career Start Year 1999

Number of shared co-authors 23

Tobias Sj??blom

Uppsala University

Career Start Year 1999

Number of shared co-authors 1

Jianjun Shen

The University of Texas MD Anderson Cancer Center

Career Start Year 1998

Number of shared co-authors 3

Lianbo Yu

The Ohio State University

Career Start Year 1997

Number of shared co-authors 0

Robert L Walker

Center for Cancer Research, National Cancer Institute, National Institutes of Health

Career Start Year 1997

Number of shared co-authors 16

Sandra Burkett

Center for Cancer Research, National Cancer Institute, National Institutes of Health

Career Start Year 1997

Number of shared co-authors 2

Agnes Viale

Memorial Sloan Kettering Cancer Center

Career Start Year 1996

Number of shared co-authors 14

Marbin Pineda

Center for Cancer Research, National Cancer Institute

Career Start Year 1995

Number of shared co-authors 11

Samuel Aparicio

University of British Columbia

Career Start Year 1993

Number of shared co-authors 40

Glenn S Cowley

Broad Institute of Harvard and MIT

Career Start Year 1990

Number of shared co-authors 10

Suzanne Carreira

The Institute of Cancer Research

Career Start Year 1990

Number of shared co-authors 6

E Alejandro Sweet-Cordero

University of California San Francisco

Career Start Year 1989

Number of shared co-authors 3

David W Threadgill

College Station

Career Start Year 1988

Number of shared co-authors 8

Eivind Hovig

Center for Bioinformatics, University of Oslo

Career Start Year 1987

Number of shared co-authors 35

Ralf Kittler

McDermott Center for Human Growth and Development.

Career Start Year 1984

Number of shared co-authors 6

Matthew Meyerson

Broad Institute

Career Start Year 1983

Number of shared co-authors 51

David D L Bowtell

Peter MacCallum Cancer Centre

Career Start Year 1983

Number of shared co-authors 40

Alan Ashworth

UCSF Helen Diller Family Comprehensive Cancer Center

Career Start Year 1982

Number of shared co-authors 27

Edison T Liu

USA The Jackson Laboratory Cancer Center

Career Start Year 1982

Number of shared co-authors 15

Alexander Kamb

Inc. 30301 Agoura Rd.

Career Start Year 1979

Number of shared co-authors 3

Stephen H Friend

University of Oxford

Career Start Year 1978

Number of shared co-authors 9

Sean Davis

Johns Hopkins School of Medicine, National Cancer Institute, Princeton University, University of Colorado Anschutz Medical Campus, University of Pittsburgh, University of Washington

Career Start Year 1974

Number of shared co-authors 62

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