Author details

Full Name

Guangping Gao

Affiliation

ORCID

Career Start Year

1994

Papers

354

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
36993169	Self-delivering CRISPR RNAs for AAV Co-delivery and Genome Editing <i>in vivo</i>.	bioRxiv	2023
36424489	Drag-and-drop genome insertion of large sequences without double-strand DNA cleavage using CRISPR-directed integrases.	Nat Biotechnol	2023
36184851	WNT-modulating gene silencers as a gene therapy for osteoporosis, bone fracture, and critical-sized bone defects.	Molecular Therapy	2023
37759764	AAV-Mediated Targeting of the Activin A-ACVR1 Signaling in Fibrodysplasia Ossificans Progressiva.		2023
37601414	Adeno-associated virus-mediated gene therapy in a patient with Canavan disease using dual routes of administration and immune modulation.		2023
37989318	NIIMBL's viral vector program: A cross-gene therapy community collaboration to transform viral vector development and manufacturing.		2023
37547286	Therapeutic inhibition of miR-155 attenuates liver fibrosis via STAT3 signaling.		2023
37153616	A strategy for high antibody expression with low anti-drug antibodies using AAV9 vectors.		2023
37280258	Durable contraception in the female domestic cat using viral-vectored delivery of a feline anti-MÃ¼llerian hormone transgene.		2023
37149081	Renewal of oligodendrocyte lineage reverses dysmyelination and CNS neurodegeneration through corrected N-acetylaspartate metabolism.	Prog Neurobiol	2023
36893269	Divalent siRNAs are bioavailable in the lung and efficiently block SARS-CoV-2 infection.	Proc Natl Acad Sci U S A	2023
37141171	Schnurri-3 inhibition suppresses bone and joint damage in models of rheumatoid arthritis.		2023
36503013	Discovery of lead natural products for developing pan-SARS-CoV-2 therapeutics.	Antiviral Res	2023
37328037	C9orf72 poly(PR) aggregation in nucleus induces ALS/FTD-related neurodegeneration in cynomolgus monkeys.		2023
37014712	Rescue of GM3 synthase deficiency by spatially controlled, rAAV-mediated ST3GAL5 delivery.		2023
37131611	Engineering Nme2Cas9 Adenine Base Editors with Improved Activity and Targeting Scope.		2023
37002158	Corrigendum to "Discovery of lead natural products for developing pan-SARS-CoV-2 therapeutics" "Antiviral Research 209 (2023)/105484".	Antiviral Res	2023
37376529	Querying Recombination Junctions of Replication-Competent Adeno-Associated Viruses in Gene Therapy Vector Preparations with Single Molecule, Real-Time Sequencing.		2023
36997680	Combinatorial design of nanoparticles for pulmonary mRNA delivery and genome editing.		2023
36996170	Base editing rescue of spinal muscular atrophy in cells and in mice.		2023
35322228	AAV-delivered suppressor tRNA overcomes a nonsense mutation in mice.	Nature	2022
35910605	Highly Effective Markerless Genetic Manipulation of Using a Mutated PheS-Based Counterselectable Marker.	Frontiers in Microbiology	2022
36369293	Impaired mitochondrial oxidative metabolism in skeletal progenitor cells leads to musculoskeletal disintegration.	Nat Commun	2022
36178359	Direct ITR-to-ITR Nanopore Sequencing of AAV Vector Genomes.	Human Gene Therapy	2022
35585789	Gene-based therapeutics for rare genetic neurodevelopmental psychiatric disorders.	Mol Ther	2022
35950212	AAV-mediated delivery of osteoblast/osteoclast-regulating miRNAs for osteoporosis therapy.	Molecular Therapy - Nucleic Acids	2022
35502479	Gene Therapy for Fibrodysplasia Ossificans Progressiva: Feasibility and Obstacles.	Hum Gene Ther	2022
36282986	<i>Letter to the Editor:</i> mRNA Vaccines in Urological Malignancies.	Hum Gene Ther	2022
36282921	Phosphorylation of RXRÎ± mediates the effect of JNK to suppress hepatic FGF21 expression and promote metabolic syndrome.	Proc Natl Acad Sci U S A	2022
35811581	Adenine Base Editing with a Single Adeno-Associated Virus Vector.		2022
36145679	Ocular Drug Delivery: Advancements and Innovations.	Pharmaceutics	2022
35988648	Paradoxical activation of transcription factor SREBP1c and de novo lipogenesis by hepatocyte-selective ATP-citrate lyase depletion in obese mice.	J Biol Chem	2022
36258013	Suppression of heterotopic ossification in fibrodysplasia ossificans progressiva using AAV gene delivery.	Nat Commun	2022
34226687	rAAV-based and intraprostatically delivered miR-34a therapeutics for efficient inhibition of prostate cancer progression.	Gene Therapy	2022
35293222	Human and Insect Cell-Produced Recombinant Adeno-Associated Viruses Show Differences in Genome Heterogeneity.	Human Gene Therapy	2022
35169297	Regulation of sclerostin by the SIRT1 stabilization pathway in osteocytes.	Cell Death and Differentiation	2022
34695545	AAV5 delivery of CRISPR-Cas9 supports effective genome editing in mouse lung airway.	Mol Ther	2022
35283274	Durability of transgene expression after rAAV gene therapy.	Molecular Therapy	2022
35344983	Aï»¿ TMPRSS2 inhibitor acts as a pan-SARS-CoV-2 prophylactic and therapeutic.	Nature	2022
34935455	Membranous Bubbles: High-Purity and High-Titer Exosomes as the Potential Solution for Adeno-Associated Viruses to Evade Neutralization?	Human Gene Therapy	2021
34182803	Low-Dose Recombinant Adeno-Associated Virus-Mediated Inhibition of Vascular Endothelial Growth Factor Can Treat Neovascular Pathologies Without Inducing Retinal Vasculitis.	Hum Gene Ther	2021
33967698	Canavan Disease as a Model for Gene Therapy-Mediated Myelin Repair.	Frontiers in Cellular Neuroscience	2021
34283643	Immune Responses to Recombinant Adenoviruses As Gene Therapy Vectors and COVID-19 Vaccines: A Two-Edged Sword.	Human Gene Therapy	2021
34003044	It Is Time to Call Anti-Asian Bias What It Is: Racism.	Human Gene Therapy	2021
33621140	Oncolytic Virus Alphavirus M1: A New and Promising Weapon to Fight Cancer.	Human Gene Therapy	2021
33782545	Large-scale molecular epidemiological analysis of AAV in a cancer patient population.	Oncogene	2021
33568518	Engineering adeno-associated viral vectors to evade innate immune and inflammatory responses.	Sci Transl Med	2021
34046041	Vectored Immunotherapeutics for Infectious Diseases: Can rAAVs Be The Game Changers for Fighting Transmissible Pathogens?	Frontiers in Immunology	2021
33995418	Novel Combinatorial MicroRNA-Binding Sites in AAV Vectors Synergistically Diminish Antigen Presentation and Transgene Immunity for Efficient and Stable Transduction.	Frontiers in Immunology	2021
33837189	Improved prime editors enable pathogenic allele correction and cancer modelling in adult mice.	Nature Communications	2021