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Author Details

Miguel Ramalho-Santos
University of Toronto
1996
62
38
Nevan J Krogan (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36028557Regulation, functions and transmission of bivalent chromatin during mammalian development.Nat Rev Mol Cell Biol2023
37696947m<sup>6</sup>A RNA methylation orchestrates transcriptional dormancy during paused pluripotency.Nat Cell Biol2023
36778216m <sup>6</sup> A RNA methylation orchestrates transcriptional dormancy during developmental pausing.bioRxiv2023
36640358Absolute scaling of single-cell transcriptomes identifies pervasive hypertranscription in adult stem and progenitor cells.Cell Rep2023
33417860Colorectal Cancer Cells Enter a Diapause-like DTP State to Survive Chemotherapy.Cell2021
33767158The deubiquitinase Usp9x regulates PRC2-mediated chromatin reprogramming during mouse development.Nat Commun2021
33514913Homotypic clustering of L1 and B1/Alu repeats compartmentalizes the 3D genome.Cell Res2021
34409306Depletion of nuclear LINE1 RNA in mouse ESCs and embryos.STAR Protoc2021
34381042Chd1 protects genome integrity at promoters to sustain hypertranscription in embryonic stem cells.Nat Commun2021
32160538Genomic Repeats Categorize Genes with Distinct Functions for Orchestrated Regulation.Cell Rep2020
32053231What Doesn't Kill You Makes You Stronger: Transposons as Dual Players in Chromatin Regulation and Genomic Variation.Bioessays2020
33010164Sex-specific epigenetic profile of inner cell mass of mice conceived in vivo or by IVF.Mol Hum Reprod2020
31485074Maternal vitamin C regulates reprogramming of DNA methylation and germline development.Nature2019
31719689Author Correction: Maternal vitamin C regulates reprogramming of DNA methylation and germline development.Nature2019
29466726Tet2 Rescues Age-Related Regenerative Decline and Enhances Cognitive Function in the Adult Mouse Brain.Cell Rep2018
29937225A LINE1-Nucleolin Partnership Regulates Early Development and ESC Identity.Cell2018
30429558Paying PIs from grants blocks talent and diversity.Nature2018
29499153The Transcriptionally Permissive Chromatin State of Embryonic Stem Cells Is Acutely Tuned to Translational Output.Cell Stem Cell2018
27989554Hypertranscription in Development, Stem Cells, and Regeneration.Dev Cell2017
28383660CHD1 loss sensitizes prostate cancer to DNA damaging therapy by promoting error-prone double-strand break repair.Ann Oncol2017
28706564Vitamin C induces specific demethylation of H3K9me2 in mouse embryonic stem cells via Kdm3a/b.Epigenetics Chromatin2017
28591571Global Hypertranscription in the Mouse Embryonic Germline.Cell Rep2017
26947063YAP Induces Human Naive Pluripotency.Cell Rep2016
27880763Inhibition of mTOR induces a paused pluripotent state.Nature2016
25480920Chd1 is essential for the high transcriptional output and rapid growth of the mouse epiblast.Development2015
26183187Unwind and transcribe: chromatin reprogramming in the early mammalian embryo.Curr Opin Genet Dev2015
25831528Emergence of hematopoietic stem and progenitor cells involves a Chd1-dependent increase in total nascent transcription.Proc Natl Acad Sci U S A2015
25428347HiTSelect: a comprehensive tool for high-complexity-pooled screen analysis.Nucleic Acids Res2015
25087892Hira-mediated H3.3 incorporation is required for DNA replication and ribosomal RNA transcription in the mouse zygote.Dev Cell2014
25409824A comparative encyclopedia of DNA elements in the mouse genome.Nature2014
25036638Systematic identification of barriers to human iPSC generation.Cell2014
23727241Bivalent chromatin marks developmental regulatory genes in the mouse embryonic germline in vivo.Cell Rep2013
24270888Somatic cells regulate maternal mRNA translation and developmental competence of mouse oocytes.Nat Cell Biol2013
23903189Histone variant H3.3 maintains a decondensed chromatin state essential for mouse preimplantation development.Development2013
23649632Smad2 is essential for maintenance of the human and mouse primed pluripotent stem cell state.J Biol Chem2013
23812591Vitamin C induces Tet-dependent DNA demethylation and a blastocyst-like state in ES cells.Nature2013
22286172Transcriptional analysis of pluripotency reveals the Hippo pathway as a barrier to reprogramming.Hum Mol Genet2012
22438827Polycomb-like 3 promotes polycomb repressive complex 2 binding to CpG islands and embryonic stem cell self-renewal.PLoS Genet2012
21179060Open chromatin in pluripotency and reprogramming.Nat Rev Mol Cell Biol2011
21499256Incomplete DNA methylation underlies a transcriptional memory of somatic cells in human iPS cells.Nat Cell Biol2011
20598875Parallel gateways to pluripotency: open chromatin in stem cells and development.Curr Opin Genet Dev2010
19587682Chd1 regulates open chromatin and pluripotency of embryonic stem cells.Nature2009
19703387iPS cells: insights into basic biology.Cell2009
18414659High-efficiency stem cell fusion-mediated assay reveals Sall4 as an enhancer of reprogramming.PLoS One2008
18950538CompMoby: comparative MobyDick for detection of cis-regulatory motifs.BMC Bioinformatics2008
17784790Systematic identification of cis-regulatory sequences active in mouse and human embryonic stem cells.PLoS Genet2007
18371358Generation of induced pluripotent stem cells in the absence of drug selection.Cell Stem Cell2007
18371332On the origin of the term "stem cell".Cell Stem Cell2007
16520820RNA interference in embryonic stem cells and the prospects for future therapies.Gene Ther2006
15351971Stem cells as probabilistic self-producing entities.Bioessays2004
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Rupa Sridharan
Wisconsin Institute for Discovery, University of Wisconsin-Madison
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Richard Humbert
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James Taylor
Johns Hopkins University
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Kevin R Brown
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Release 1.2