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Author Details
Full Name
Alexander Karlas
Affiliation
Max Planck Institute for Infection Biology
ORCID
Career Start Year
2003
Papers
34
H Index
21
Expertise
CM4AI Collaborator
Nevan J Krogan (CM4AI)
PMID
Paper Title
Journal Title
Published Year
37515193
Relevance of Host Cell Surface Glycan Structure for Cell Specificity of Influenza A Viruses.
Viruses
2023
32866611
Expression, purification and crystallization of CLK1 kinase - A potential target for antiviral therapy.
Protein Expr Purif
2020
30883607
RNAi-based small molecule repositioning reveals clinically approved urea-based kinase inhibitors as broadly active antivirals.
PLoS Pathog
2019
31176694
Regulation of influenza A virus mRNA splicing by CLK1.
Antiviral Res
2019
31005427
Efficient influenza A virus production in high cell density using the novel porcine suspension cell line PBG.PK2.1.
Vaccine
2019
30973879
Model-based analysis of influenza A virus replication in genetically engineered cell lines elucidates the impact of host cell factors on key kinetic parameters of virus growth.
PLoS Comput Biol
2019
29937069
Long-Term Culture of Distal Airway Epithelial Cells Allows Differentiation Towards Alveolar Epithelial Cells Suited for Influenza Virus Studies.
EBioMedicine
2018
28877472
ALPK1- and TIFA-Dependent Innate Immune Response Triggered by the Helicobacter pylori Type IV Secretion System.
Cell Rep
2017
28289176
Quantitative Proteomic Approach Identifies Vpr Binding Protein as Novel Host Factor Supporting Influenza A Virus Infections in Human Cells.
Mol Cell Proteomics
2017
26914510
Genetic characterization of an adapted pandemic 2009 H1N1 influenza virus that reveals improved replication rates in human lung epithelial cells.
Virology
2016
27177310
A human genome-wide loss-of-function screen identifies effective chikungunya antiviral drugs.
Nat Commun
2016
26651948
Meta- and Orthogonal Integration of Influenza "OMICs" Data Defines a Role for UBR4 in Virus Budding.
Cell Host Microbe
2015
24440876
Evidence for a crucial role of a host non-coding RNA in influenza A virus replication.
RNA Biol
2014
25116793
Dynamin-mediated lipid acquisition is essential for Chlamydia trachomatis development.
Mol Microbiol
2014
23791642
RORγt⺠innate lymphoid cells acquire a proinflammatory program upon engagement of the activating receptor NKp44.
Immunity
2013
21431699
Genome-wide RNAi screen for viral replication in mammalian cell culture.
Methods Mol Biol
2011
21676957
Cigarette smoke extract induces prolonged endoplasmic reticulum stress and autophagic cell death in human umbilical vein endothelial cells.
Cardiovasc Res
2011
21464618
Autophagy-independent function of MAP-LC3 during intracellular propagation of Chlamydia trachomatis.
Autophagy
2011
20081832
Genome-wide RNAi screen identifies human host factors crucial for influenza virus replication.
Nature
2010
20824309
Pulmonary gene silencing in transgenic EGFP mice using aerosolised chitosan/siRNA nanoparticles.
Pharm Res
2010
20657519
Characterisation of a human cell-adapted porcine endogenous retrovirus PERV-A/C.
Ann Transplant
2010
20209161
Helicobacter pylori induces miR-155 in T cells in a cAMP-Foxp3-dependent manner.
PLoS One
2010
19060882
Chlamydia causes fragmentation of the Golgi compartment to ensure reproduction.
Nature
2009
19816566
Rab6 and Rab11 regulate Chlamydia trachomatis development and golgin-84-dependent Golgi fragmentation.
PLoS Pathog
2009
18344940
No transmission of porcine endogenous retroviruses (PERVs) in a long-term pig to rat xenotransplantation model and no infection of immunosuppressed rats.
Ann Transplant
2008
17217431
The Helicobacter pylori CagA protein disrupts matrix adhesion of gastric epithelial cells by dephosphorylation of vinculin.
Cell Microbiol
2007
17510655
Conserved roles of Sam50 and metaxins in VDAC biogenesis.
EMBO Rep
2007
17106623
Inhibition of porcine endogenous retroviruses (PERVs) in primary porcine cells by RNA interference using lentiviral vectors.
Arch Virol
2007
15812191
Porcine endogenous retroviruses PERV-A and PERV-B infect neither mouse cells in vitro nor SCID mice in vivo.
Intervirology
2005
15864489
Analysis of pig-to-human porcine endogenous retrovirus transmission in a triple-species kidney xenotransplantation model.
Transpl Int
2005
15231382
Inhibition of porcine endogenous retroviruses by RNA interference: increasing the safety of xenotransplantation.
Virology
2004
15528741
Monitoring for presence of potentially xenotic viruses in recipients of pig islet xenotransplantation.
J Clin Microbiol
2004
14517066
Genetic alterations of the long terminal repeat of an ecotropic porcine endogenous retrovirus during passage in human cells.
Virology
2003
12957184
Porcine endogenous retroviruses: no infection in patients treated with a bioreactor based on porcine liver cells.
J Clin Virol
2003
1 - 34 of 34
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