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Author Details

Jill P Mesirov
University of California San Diego
1992
137
70
Trey Ideker (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36562559igv.js: an embeddable JavaScript implementation of the Integrative Genomics Viewer (IGV).Bioinformatics2023
37945900Circular extrachromosomal DNA promotes tumor heterogeneity in high-risk medulloblastoma.Nat Genet2023
37989764Inferring cellular and molecular processes in single-cell data with non-negative matrix factorization using Python, R and GenePattern Notebook implementations of CoGAPS.Nat Protoc2023
37704782Extending support for mouse data in the Molecular Signatures Database (MSigDB).Nat Methods2023
370855393D genome mapping identifies subgroup-specific chromosome conformations and tumor-dependency genes in ependymoma.Nat Commun2023
37398372NMFClustering: Accessible NMF-based clustering utilizing GPU acceleration.bioRxiv2023
36562559igv.js: an embeddable JavaScript implementation of the Integrative Genomics Viewer (IGV).Bioinformatics2023
37066251Genomics to Notebook (g2nb): extending the electronic notebook to address the challenges of bioinformatics analysis.bioRxiv2023
37308665The GPCR-Gα<sub>s</sub>-PKA signaling axis promotes T cell dysfunction and cancer immunotherapy failure.Nat Immunol2023
37173324Germline modifiers of the tumor immune microenvironment implicate drivers of cancer risk and immunotherapy response.Nat Commun2023
37704782Extending support for mouse data in the Molecular Signatures Database (MSigDB).Nat Methods2023
37945900Circular extrachromosomal DNA promotes tumor heterogeneity in high-risk medulloblastoma.Nat Genet2023
37989764Inferring cellular and molecular processes in single-cell data with non-negative matrix factorization using Python, R and GenePattern Notebook implementations of CoGAPS.Nat Protoc2023
370855393D genome mapping identifies subgroup-specific chromosome conformations and tumor-dependency genes in ependymoma.Nat Commun2023
37308665The GPCR-Gα<sub>s</sub>-PKA signaling axis promotes T cell dysfunction and cancer immunotherapy failure.Nat Immunol2023
37173324Germline modifiers of the tumor immune microenvironment implicate drivers of cancer risk and immunotherapy response.Nat Commun2023
37398372NMFClustering: Accessible NMF-based clustering utilizing GPU acceleration.bioRxiv2023
37066251Genomics to Notebook (g2nb): extending the electronic notebook to address the challenges of bioinformatics analysis.bioRxiv2023
34667113A FZD7-specific Antibody-Drug Conjugate Induces Ovarian Tumor Regression in Preclinical Models.Mol Cancer Ther2022
35715421Single-cell characterization of step-wise acquisition of carboplatin resistance in ovarian cancer.NPJ Syst Biol Appl2022
35879302Lymphatic-preserving treatment sequencing with immune checkpoint inhibition unleashes cDC1-dependent antitumor immunity in HNSCC.Nat Commun2022
35977718Subgroup-Enriched Pathways and Kinase Signatures in Medulloblastoma Patient-Derived Xenografts.J Proteome Res2022
34667113A FZD7-specific Antibody-Drug Conjugate Induces Ovarian Tumor Regression in Preclinical Models.Mol Cancer Ther2022
35715421Single-cell characterization of step-wise acquisition of carboplatin resistance in ovarian cancer.NPJ Syst Biol Appl2022
35977718Subgroup-Enriched Pathways and Kinase Signatures in Medulloblastoma Patient-Derived Xenografts.J Proteome Res2022
35879302Lymphatic-preserving treatment sequencing with immune checkpoint inhibition unleashes cDC1-dependent antitumor immunity in HNSCC.Nat Commun2022
33428749PTEN deficiency leads to proteasome addiction: a novel vulnerability in glioblastoma.Neuro Oncol2021
33571541TORC1/2 kinase inhibition depletes glutathione and synergizes with carboplatin to suppress the growth of MYC-driven medulloblastoma.Cancer Lett2021
34095869A phenotypically supervised single-cell analysis protocol to study within-cell-type heterogeneity of cultured mammalian cells.STAR Protoc2021
34326133Location of Gastrointestinal Stromal Tumor (GIST) in the Stomach Predicts Tumor Mutation Profile and Drug Sensitivity.Clin Cancer Res2021
33428749PTEN deficiency leads to proteasome addiction: a novel vulnerability in glioblastoma.Neuro Oncol2021
34376580KIT<sup>low</sup> Cells Mediate Imatinib Resistance in Gastrointestinal Stromal Tumor.Mol Cancer Ther2021
34761247Model-based assessment of mammalian cell metabolic functionalities using omics data.Cell Rep Methods2021
33571541TORC1/2 kinase inhibition depletes glutathione and synergizes with carboplatin to suppress the growth of MYC-driven medulloblastoma.Cancer Lett2021
34761247Model-based assessment of mammalian cell metabolic functionalities using omics data.Cell Rep Methods2021
34376580KIT<sup>low</sup> Cells Mediate Imatinib Resistance in Gastrointestinal Stromal Tumor.Mol Cancer Ther2021
34326133Location of Gastrointestinal Stromal Tumor (GIST) in the Stomach Predicts Tumor Mutation Profile and Drug Sensitivity.Clin Cancer Res2021
34095869A phenotypically supervised single-cell analysis protocol to study within-cell-type heterogeneity of cultured mammalian cells.STAR Protoc2021
32383980Imaging-AMARETTO: An Imaging Genomics Software Tool to Interrogate Multiomics Networks for Relevance to Radiography and Histopathology Imaging Biomarkers of Clinical Outcomes.JCO Clin Cancer Inform2020
32383980Imaging-AMARETTO: An Imaging Genomics Software Tool to Interrogate Multiomics Networks for Relevance to Radiography and Histopathology Imaging Biomarkers of Clinical Outcomes.JCO Clin Cancer Inform2020
33046443Functional Precision Medicine Identifies New Therapeutic Candidates for Medulloblastoma.Cancer Res2020
33046443Functional Precision Medicine Identifies New Therapeutic Candidates for Medulloblastoma.Cancer Res2020
30559381Addendum: The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.Nature2019
31624069Biallelic loss of <i>GNAS</i> in a patient with pediatric medulloblastoma.Cold Spring Harb Mol Case Stud2019
31754034Inhibition of dual-specificity tyrosine phosphorylation-regulated kinase 2 perturbs 26S proteasome-addicted neoplastic progression.Proc Natl Acad Sci U S A2019
30559381Addendum: The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.Nature2019
30864324Precision Medicine: Improving health through high-resolution analysis of personal data.Pac Symp Biocomput2019
31754034Inhibition of dual-specificity tyrosine phosphorylation-regulated kinase 2 perturbs 26S proteasome-addicted neoplastic progression.Proc Natl Acad Sci U S A2019
31624069Biallelic loss of <i>GNAS</i> in a patient with pediatric medulloblastoma.Cold Spring Harb Mol Case Stud2019
30864324Precision Medicine: Improving health through high-resolution analysis of personal data.Pac Symp Biocomput2019
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Collaborators

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Co-authored papers 66
Vanderbilt-Ingram Cancer Center, Vanderbilt University
Co-authored papers 24
Broad Institute of MIT and Harvard
Co-authored papers 17
Broad Institute of MIT and Harvard, USA Dana-Farber Cancer Institute
Co-authored papers 15
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Co-authored papers 15
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Co-authored papers 13
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Co-authored papers 13
Broad Institute
Co-authored papers 12
Harvard Medical School
Co-authored papers 12
Moores Cancer Center, University of California San Diego
Co-authored papers 12
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Co-authored papers 11
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Broad Institute of Massachusetts Institute of Technology (MIT) and Harvard
Co-authored papers 10
Janssen Research and Development LLC
Co-authored papers 10
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Co-authored papers 10
Broad Institute of MIT and Harvard
Co-authored papers 9
Broad Institute of Harvard and MIT
Co-authored papers 8
Broad Institute of Harvard and MIT
Co-authored papers 8
Dana-Farber Cancer Institute
Co-authored papers 8
Broad Institute of MIT and Harvard
Co-authored papers 7
Sanford Burnham Prebys Medical Discovery Institute
Co-authored papers 6
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The Broad Institute
Co-authored papers 6
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Co-authored papers 5
Dana-Farber Cancer Institute
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Broad Institute of MIT and Harvard
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Hopp Children's Cancer Center (KiTZ)
Co-authored papers 5
University of California San Diego
Co-authored papers 5