Author details

Full Name

Deborah G Murdock

Affiliation

Center for Mitochondrial and Epigenomic Medicine, Children's Hospital of Philadelphia

ORCID

Career Start Year

1993

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
36891303	SARS-COV-2 viroporins activate the NLRP3-inflammasome by the mitochondrial permeability transition pore.	Front Immunol	2023
37556555	Core mitochondrial genes are down-regulated during SARS-CoV-2 infection of rodent and human hosts.	Sci Transl Med	2023
35233572	TARGETED DOWN REGULATION OF CORE MITOCHONDRIAL GENES DURING SARS-COV-2 INFECTION.	bioRxiv	2022
36322731	Combination of common mtDNA variants results in mitochondrial dysfunction and a connective tissue dysregulation.	Proc Natl Acad Sci U S A	2022
30861524	Premature Lambs Exhibit Normal Mitochondrial Respiration after Long-Term Extrauterine Support.	Fetal Diagn Ther	2019
31385882	Persistent Mitochondrial Dysfunction Linked to Prolonged Organ Dysfunction in Pediatric Sepsis.	Crit Care Med	2019
31266851	Host mitochondria influence gut microbiome diversity: A role for ROS.	Sci Signal	2019
29967758	Hi-MC: a novel method for high-throughput mitochondrial haplogroup classification.	PeerJ	2018
29968489	Hemochromatosis (HFE) Gene Variants Are Associated with Increased Mitochondrial DNA Levels During HIV-1 Infection and Antiretroviral Therapy.	AIDS Res Hum Retroviruses	2018
28223503	Mitochondrial energy deficiency leads to hyperproliferation of skeletal muscle mitochondria and enhanced insulin sensitivity.	Proc Natl Acad Sci U S A	2017
26963735	Altering the Mitochondrial Fatty Acid Synthesis (mtFASII) Pathway Modulates Cellular Metabolic States and Bioactive Lipid Profiles as Revealed by Metabolomic Profiling.	PLoS One	2016
25592585	Mitochondrial variation and the risk of age-related macular degeneration across diverse populations.	Pac Symp Biocomput	2015
26129753	Mitochondrial DNA Haplogroups and Neurocognitive Impairment During HIV Infection.	Clin Infect Dis	2015
24488180	Characterization of mitochondrial haplogroups in a large population-based sample from the United States.	Hum Genet	2014
25144566	Genetic variation in iron metabolism is associated with neuropathic pain and pain severity in HIV-infected patients on antiretroviral therapy.	PLoS One	2014
24785954	Epidermal nerve fiber density, oxidative stress, and mitochondrial haplogroups in HIV-infected Thais initiating therapy.	AIDS	2014
23944767	Mitochondrial DNA variation and changes in adiponectin and endothelial function in HIV-infected adults after antiretroviral therapy initiation.	AIDS Res Hum Retroviruses	2013
24349219	KIAA1462, a coronary artery disease associated gene, is a candidate gene for late onset Alzheimer disease in APOE carriers.	PLoS One	2013
24161390	The mitochondrial fatty acid synthesis (mtFASII) pathway is capable of mediating nuclear-mitochondrial cross talk through the PPAR system of transcriptional activation.	Biochem Biophys Res Commun	2013
24244193	Recurrent tissue-specific mtDNA mutations are common in humans.	PLoS Genet	2013
22459207	Peptide tyrosine tyrosine levels are increased in patients with urea cycle disorders.	Mol Genet Metab	2012
22970105	T cell activation markers and African mitochondrial DNA haplogroups among non-Hispanic black participants in AIDS clinical trials group study 384.	PLoS One	2012
22943764	Identification and confirmation of an exonic splicing enhancer variation in exon 5 of the Alzheimer disease associated PICALM gene.	Ann Hum Genet	2012
21972221	Decreased cytochrome c oxidase subunit VIIa in aged rat heart mitochondria: immunocytochemistry.	Anat Rec (Hoboken)	2011
21792066	Mitochondrial genomics and CD4 T-cell count recovery after antiretroviral therapy initiation in AIDS clinical trials group study 384.	J Acquir Immune Defic Syndr	2011
20402593	African mitochondrial DNA subhaplogroups and peripheral neuropathy during antiretroviral therapy.	J Infect Dis	2010
17684475	The mitochondrial pharmacogenomics of haplogroup T: MTND2*LHON4917G and antiretroviral therapy-associated peripheral neuropathy.	Pharmacogenomics J	2008
18505419	A genome-wide scan in an Amish pedigree with parkinsonism.	Ann Hum Genet	2008
18439414	MITOCHIP assessment of differential gene expression in the skeletal muscle of Ant1 knockout mice: coordinate regulation of OXPHOS, antioxidant, and apoptotic genes.	Biochim Biophys Acta	2008
15814615	Structure theorems and the dynamics of nitrogen catabolite repression in yeast.	Proc Natl Acad Sci U S A	2005
16214533	Cardioplegia prevents ischemia-induced transcriptional alterations of cytoprotective genes in rat hearts: a DNA microarray study.	J Thorac Cardiovasc Surg	2005
12727119	Targeted delivery of DNA to the mitochondrial compartment via import sequence-conjugated peptide nucleic acid.	Mol Ther	2003
12229286	PNA-mediated PCR clamping. Applications and methods.	Methods Mol Biol	2002
11058135	The age-related accumulation of a mitochondrial DNA control region mutation in muscle, but not brain, detected by a sensitive PNA-directed PCR clamping based method.	Nucleic Acids Res	2000
10051550	Mitochondria and dystonia: the movement disorder connection?	Proc Natl Acad Sci U S A	1999
10318868	Up-regulation of nuclear and mitochondrial genes in the skeletal muscle of mice lacking the heart/muscle isoform of the adenine nucleotide translocator.	J Biol Chem	1999
9405711	Ancient mtDNA sequences in the human nuclear genome: a potential source of errors in identifying pathogenic mutations.	Proc Natl Acad Sci U S A	1997
8465604	The VPH2 gene encodes a 25 kDa protein required for activity of the yeast vacuolar H(+)-ATPase.	Yeast	1993

1 - 38 of 38

Lara Strittmatter

University of Massachusetts Chan Medical School

Career Start Year 2011

Number of shared co-authors 0

Ren?? G Feichtinger

Paracelsus Medical University

Career Start Year 2008

Number of shared co-authors 0

Monika Ol??hov??

Translational and Clinical Research Institute, Newcastle University

Career Start Year 2008

Number of shared co-authors 1

Vamsi K Mootha

Broad Institute of MIT and Harvard

Career Start Year 1996

Number of shared co-authors 0

Kenneth B Beckman

University of Minnesota Genomics Center (UMNGC)

Career Start Year 1996

Number of shared co-authors 1

Johannes A Mayr

University Children's Hospital, Paracelsus Medical University

Career Start Year 1996

Number of shared co-authors 0

Francois H van der Westhuizen

North-West University

Career Start Year 1996

Number of shared co-authors 0

Shamima Rahman

UCL Great Ormond Street Institute of Child Health

Career Start Year 1994

Number of shared co-authors 1

Janine H Santos

National Institute of Environmental Health Sciences

Career Start Year 1992

Number of shared co-authors 0

Robert W Taylor

Newcastle upon Tyne Hospitals NHS Foundation Trust

Career Start Year 1992

Number of shared co-authors 2

Simon Melov

Buck Institute for Research on Aging

Career Start Year 1992

Number of shared co-authors 0

Rita Horvath

School of Clinical Medicine, University of Cambridge

Career Start Year 1991

Number of shared co-authors 2

Giovanni Manfredi

Brain and Mind Research Institute

Career Start Year 1991

Number of shared co-authors 0

Patrick F Chinnery

School of Clinical Medicine, University of Cambridge

Career Start Year 1990

Number of shared co-authors 2

Andrew A Hicks

Institute for Biomedicine, Affiliated institute of the University of Lubeck

Career Start Year 1990

Number of shared co-authors 5

Yasushi Okazaki

Intractable Disease Research Center, Graduate School of Medicine, Juntendo University

Career Start Year 1989

Number of shared co-authors 0

Gerald S Shadel

Salk Institute for Biological Studies

Career Start Year 1989

Number of shared co-authors 1

Keshav K Singh

Heersink School of Medicine, University of Alabama at Birmingham

Career Start Year 1988

Number of shared co-authors 0

Hubert J M Smeets

Maastricht University Medical Centre+

Career Start Year 1987

Number of shared co-authors 2

Michael R Erdos

Center for Precision Health Research, National Human Genome Research Institute

Career Start Year 1986

Number of shared co-authors 3

Robert K Naviaux

University of California, San Diego School of Medicine

Career Start Year 1986

Number of shared co-authors 0

Russell H Swerdlow

University of Kansas Alzheimer's Disease Research Centre

Career Start Year 1984

Number of shared co-authors 5

Thomas Meitinger

Technical University of Munich, Institute of Human Genetics

Career Start Year 1982

Number of shared co-authors 10

Richard Haas

University of California

Career Start Year 1981

Number of shared co-authors 0

Douglass M Turnbull

Newcastle University

Career Start Year 1980

Number of shared co-authors 1

Eric A Shoubridge

McGill University

Career Start Year 1976

Number of shared co-authors 0

Robert L Nussbaum

Invitae Corporation

Career Start Year 1976

Number of shared co-authors 1

David Valle

Johns Hopkins School of Medicine

Career Start Year 1973

Number of shared co-authors 2

David M Koeller

Oregon Health & Science University

Career Start Year 1970

Number of shared co-authors 0

John Christodoulou

University of Melbourne, The Royal Children's Hospital

Career Start Year 1969

Number of shared co-authors 1

row(s) 1 - 30 of 30

Douglas C Wallace

Co-authored papers 15

Todd Hulgan

Vanderbilt University Medical Center

Co-authored papers 9

David C Samuels

Vanderbilt University

Co-authored papers 7

David W Haas

Vanderbilt University Medical Center

Co-authored papers 6

David B Clifford

Washington University School of Medicine

Co-authored papers 5

Jonathan L Haines

Cleveland Institute for Computational Biology, Case Western Reserve University

Co-authored papers 5

Asha R Kallianpur

Cleveland Clinic/Lerner Research Institute

Co-authored papers 5

Justin C McArthur

Johns Hopkins School of Medicine

Co-authored papers 4

Larry N Singh

Center for Mitochondrial and Epigenomic Medicine, Children's Hospital of Philadelphia

Co-authored papers 4

Robert W Shafer

Co-authored papers 4

Gregory K Robbins

Co-authored papers 4

Marylyn D Ritchie

Center for Systems Genomics, Pennsylvania State University, University Park

Co-authored papers 4

Dana C Crawford

Cleveland Institute for Computational Biology, Case Western Reserve University

Co-authored papers 4

David M Simpson

Icahn School of Medicine at Mount Sinai

Co-authored papers 3

Doug Selph

Co-authored papers 3

Scott L Weiss

Sidney Kimmel Medical College at Thomas Jefferson University

Co-authored papers 3

Scott L Letendre

University of California, university of california san diego

Co-authored papers 2

Sonja M Best

National Institute of Allergy and Infectious Diseases, National Institutes of Health

Co-authored papers 2

Ann C Collier

University of Washington

Co-authored papers 2

Ronald J Ellis

University of California

Co-authored papers 2

Benjamin B Gelman

University of Texas Medical Branch

Co-authored papers 2

Yuki Bradford

University of Pennsylvania

Co-authored papers 2

Hossein Fazelinia

Co-authored papers 2

Afshin Beheshti

Co-authored papers 2

Margaret A Pericak-Vance

Co-authored papers 2

Yared H Kidane

Co-authored papers 2

Robert Meller

Co-authored papers 2

Mark T Heise

University of North Carolina at Chapel Hill.

Co-authored papers 2

Yuanchao Zhang

Co-authored papers 2

Jonathan C Schisler

Co-authored papers 2

1 - 30

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