Author details

Full Name

Jun Zhu

Affiliation

ORCID

Career Start Year

2004

Papers

111

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
35158979	Early-Stage Lung Adenocarcinoma MDM2 Genomic Amplification Predicts Clinical Outcome and Response to Targeted Therapy.	Cancers (Basel)	2022
35848993	Transcriptional Circuitry of NKX2-1 and SOX1 Defines an Unrecognized Lineage Subtype of Small-Cell Lung Cancer.	American Journal of Respiratory and Critical Care Medicine	2022
35483740	Functional dissection of human mitotic genes using CRISPR-Cas9 tiling screens.	Genes and Development	2022
35332150	Integrative network analysis of early-stage lung adenocarcinoma identifies aurora kinase inhibition as interceptor of invasion and progression.	Nat Commun	2022
35239955	Global DNA methylation of WTC prostate cancer tissues show signature differences compared to non-exposed cases.	Carcinogenesis	2022
34780722	Integrative Analysis of the Inflammatory Bowel Disease Serum Metabolome Improves Our Understanding of Genetic Etiology and Points to Novel Putative Therapeutic Targets.	Gastroenterology	2022
35071255	Effect of Hyperinsulinemia and Insulin Resistance on Endocrine, Metabolic, and Reproductive Outcomes in Non-PCOS Women Undergoing Assisted Reproduction: A Retrospective Cohort Study.	Frontiers in Medicine	2021
33483510	An integrative multiomic network model links lipid metabolism to glucose regulation in coronary artery disease.	Nat Commun	2021
33514539	Prototypical oncogene family Myc defines unappreciated distinct lineage states of small cell lung cancer.	Science advances	2021
33564792	A Molecular network approach reveals shared cellular and molecular signatures between chronic fatigue syndrome and other fatiguing illnesses.	medRxiv	2021
34036290	A community effort to identify and correct mislabeled samples in proteogenomic studies.	Patterns (N Y)	2021
32980345	Intestinal Inflammation Modulates the Expression of ACE2 and TMPRSS2 and Potentially Overlaps With the Pathogenesis of SARS-CoV-2-related Disease.	Gastroenterology	2021
33238137	Transformative Network Modeling of Multi-omics Data Reveals Detailed Circuits, Key Regulators, and Potential Therapeutics for Alzheimer's Disease.	Neuron	2021
34398535	Examining heterogeneity of stromal cells in tumor microenvironment based on pan-cancer single-cell RNA sequencing data.	Cancer Biology and Medicine	2021
34381049	Downregulation of exhausted cytotoxic T cells in gene expression networks of multisystem inflammatory syndrome in children.	Nat Commun	2021
35008302	Identification of Let-7 miRNA Activity as a Prognostic Biomarker of SHH Medulloblastoma.	Cancers (Basel)	2021
34480882	Molecular Characterization of Limited Ulcerative Colitis Reveals Novel Biology and Predictors of Disease Extension.	Gastroenterology	2021
32770063	Multiscale causal networks identify VGF as a key regulator of Alzheimer's disease.	Nat Commun	2020
32024511	Comparison of brain connectomes by MRI and genomics and its implication in Alzheimer's disease.	BMC Med	2020
32077223	Transcriptome analysis reveals the difference between "healthy" and "common" aging and their connection with age-related diseases.	Aging Cell	2020
31637571	Human geroprotector discovery by targeting the converging subnetworks of aging and age-related diseases.	Geroscience	2020
32111252	A reference profile-free deconvolution method to infer cancer cell-intrinsic subtypes and tumor-type-specific stromal profiles.	Genome Med	2020
32909006	Cytotoxic lymphocytes are dysregulated in multisystem inflammatory syndrome in children.	medRxiv	2020
31100034	Computational deconvolution of synovial tissue cellular composition: presence of adipocytes in synovial tissue decreased during arthritis pathogenesis and progression.	Physiological Genomics	2019
31569720	A Network Analysis of Multiple Myeloma Related Gene Signatures.	Cancers (Basel)	2019
31551362	Epigenomic Profiling Discovers Trans-lineage SOX2 Partnerships Driving Tumor Heterogeneity in Lung Squamous Cell Carcinoma.	Cancer Research	2019
31289834	A probabilistic multi-omics data matching method for detecting sample errors in integrative analysis.	Gigascience	2019
30745909	Exome Sequencing Identifies <i>TENM4</i> as a Novel Candidate Gene for Schizophrenia in the SCZD2 Locus at 11q14-21.	Front Genet	2019
31272788	Fibroblast Growth Factor Receptor 3 Alterations and Response to PD-1/PD-L1 Blockade in Patients with Metastatic Urothelial Cancer.		2019
31221798	Prostate Cancer in World Trade Center Responders Demonstrates Evidence of an Inflammatory Cascade.	Molecular Cancer Research	2019
30949676	The polarity protein Scrib limits atherosclerosis development in mice.	Cardiovasc Res	2019
30666957	Gut microbiota density influences host physiology and is shaped by host and microbial factors.	Elife	2019
29138345	Novel Predictors of Breast Cancer Survival Derived from miRNA Activity Analysis.	Clin Cancer Res	2018
30266904	Temporal genetic association and temporal genetic causality methods for dissecting complex networks.	Nat Commun	2018
30072576	Co-regulatory networks of human serum proteins link genetics to disease.	Science	2018
30158554	EMT- and stroma-related gene expression and resistance to PD-1 blockade in urothelial cancer.	Nature Communications	2018
29970902	Identification of microR-106b as a prognostic biomarker of p53-like bladder cancers by ActMiR.	Oncogene	2018
30150281	Comprehensive innate immune profiling of chikungunya virus infection in pediatric cases.	Mol Syst Biol	2018
29949994	A new method for constructing tumor specific gene co-expression networks based on samples with tumor purity heterogeneity.		2018
30031763	Comparison of glioblastoma (GBM) molecular classification methods.	Semin Cancer Biol	2018
29895827	Oxidized phospholipids regulate amino acid metabolism through MTHFD2 to facilitate nucleotide release in endothelial cells.	Nat Commun	2018
27896968	EXPLORING THE REPRODUCIBILITY OF PROBABILISTIC CAUSAL MOLECULAR NETWORK MODELS.	Pac Symp Biocomput	2017
28855212	Sensitivity to <i>BUB1B</i> Inhibition Defines an Alternative Classification of Glioblastoma.	Cancer Res	2017
28892060	A functional genomics predictive network model identifies regulators of inflammatory bowel disease.	Nat Genet	2017
29036320	Detect differentially methylated regions using non-homogeneous hidden Markov model for methylation array data.		2017
29273013	A next generation sequencing based approach to identify extracellular vesicle mediated mRNA transfers between cells.	BMC Genomics	2017
29212479	A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis.	BMC Med	2017
29162888	miR-500a-5p regulates oxidative stress response genes in breast cancer and predicts cancer survival.	Sci Rep	2017
29416795	Treatment-associated <i>TP53</i> DNA-binding domain missense mutations in the pathogenesis of secondary gliosarcoma.	Oncotarget	2017
29110684	Multiscale network modeling of oligodendrocytes reveals molecular components of myelin dysregulation in Alzheimer's disease.	Mol Neurodegener	2017