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Author Details

Louis J Picker
Vaccine and Gene Therapy Institute, Oregon Health & Science University
1980
227
87
Nevan J Krogan (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36894436Programming cytomegalovirus as an HIV vaccine.Trends Immunol2023
37398229The pentameric complex is not required for vertical transmission of cytomegalovirus in seronegative pregnant rhesus macaques.bioRxiv2023
36749635Late gene expression-deficient cytomegalovirus vectors elicit conventional T cells that do not protect against SIV.JCI Insight2023
35041707The ingenol-based protein kinase C agonist GSK445A is a potent inducer of HIV and SIV RNA transcription.PLoS Pathog2022
35561167BFF and cellhashR: analysis tools for accurate demultiplexing of cell hashing data.Bioinformatics2022
35714200Myeloid cell tropism enables MHC-E-restricted CD8<sup>+</sup> T cell priming and vaccine efficacy by the RhCMV/SIV vaccine.Sci Immunol2022
36536032Alternative splicing and genetic variation of mhc-e: implications for rhesus cytomegalovirus-based vaccines.Commun Biol2022
35981532Cytomegalovirus-vaccine-induced unconventional T cell priming and control of SIV replication is conserved between primate species.Cell Host Microbe2022
35316218Rapamycin limits CD4+ T cell proliferation in simian immunodeficiency virus-infected rhesus macaques on antiretroviral therapy.J Clin Invest2022
33142108Ultra-low Dose Aerosol Infection of Mice with Mycobacterium tuberculosis More Closely Models Human Tuberculosis.Cell Host Microbe2021
33766941Modulation of MHC-E transport by viral decoy ligands is required for RhCMV/SIV vaccine efficacy.Science2021
33766849Cytomegaloviral determinants of CD8[+] T cell programming and RhCMV/SIV vaccine efficacy.Sci Immunol2021
33766848HLA-E-restricted, Gag-specific CD8<sup>+</sup> T cells can suppress HIV-1 infection, offering vaccine opportunities.Sci Immunol2021
33711270TGFβ restricts expansion, survival, and function of T cells within the tuberculous granuloma.Cell Host Microbe2021
33536176Evaluating a New Class of AKT/mTOR Activators for HIV Latency Reversing Activity <i>Ex Vivo and In Vivo</i>.J Virol2021
33630764CD8+ T cells fail to limit SIV reactivation following ART withdrawal until after viral amplification.J Clin Invest2021
34810222Identification and Characterization of Antigen-Specific CD8<sup>+</sup> T Cells Using Surface-Trapped TNF-α and Single-Cell Sequencing.J Immunol2021
34485613Immune inactivation of anti-simian immunodeficiency virus chimeric antigen receptor T cells in rhesus macaques.Mol Ther Methods Clin Dev2021
34228762Interleukin-15 response signature predicts RhCMV/SIV vaccine efficacy.PLoS Pathog2021
32161099MHC-E-Restricted CD8<sup>+</sup> T Cells Target Hepatitis B Virus-Infected Human Hepatocytes.J Immunol2020
33335035Sequence diversity analyses of an improved rhesus macaque genome enhance its biomedical utility.Science2020
32376650Systematic Profiling of Full-Length Ig and TCR Repertoire Diversity in Rhesus Macaque through Long Read Transcriptome Sequencing.J Immunol2020
30430748Lymph nodes as barriers to T-cell rejuvenation in aging mice and nonhuman primates.Aging Cell2019
31653683Role of IL-15 Signaling in the Pathogenesis of Simian Immunodeficiency Virus Infection in Rhesus Macaques.J Immunol2019
31848362Characterization of a live-attenuated HCMV-based vaccine platform.Sci Rep2019
31295427The Landscape of Persistent Viral Genomes in ART-Treated SIV, SHIV, and HIV-2 Infections.Cell Host Microbe2019
31316007A live-attenuated RhCMV/SIV vaccine shows long-term efficacy against heterologous SIV challenge.Sci Transl Med2019
31316006Enhancing safety of cytomegalovirus-based vaccine vectors by engaging host intrinsic immunity.Sci Transl Med2019
31315990Vaccine-Mediated Inhibition of the Transporter Associated with Antigen Processing Is Insufficient To Induce Major Histocompatibility Complex E-Restricted CD8<sup>+</sup> T Cells in Nonhuman Primates.J Virol2019
31597757<i>In Vivo</i> Validation of the Viral Barcoding of Simian Immunodeficiency Virus SIVmac239 and the Development of New Barcoded SIV and Subtype B and C Simian-Human Immunodeficiency Viruses.J Virol2019
30789961Casting a wider net: Immunosurveillance by nonclassical MHC molecules.PLoS Pathog2019
30487278Identification and Functional Characterization of a Novel Fc Gamma-Binding Glycoprotein in Rhesus Cytomegalovirus.J Virol2019
30673723Cytomegalovirus vectors expressing Plasmodium knowlesi antigens induce immune responses that delay parasitemia upon sporozoite challenge.PLoS One2019
30333177Acute Infection and Subsequent Subclinical Reactivation of Herpes Simplex Virus 2 after Vaginal Inoculation of Rhesus Macaques.J Virol2019
29150562The Role of MHC-E in T Cell Immunity Is Conserved among Humans, Rhesus Macaques, and Cynomolgus Macaques.J Immunol2018
30220351Corrigendum to 'Unusual antigen presentation offers new insight into HIV vaccine design' [Curr Opin Immunol 46 (2017) 75-81].Curr Opin Immunol2018
30082858Early antiretroviral therapy limits SIV reservoir establishment to delay or prevent post-treatment viral rebound.Nat Med2018
30087334Pathogen-derived HLA-E bound epitopes reveal broad primary anchor pocket tolerability and conformationally malleable peptide binding.Nat Commun2018
30420666Author Correction: Pathogen-derived HLA-E bound epitopes reveal broad primary anchor pocket tolerability and conformationally malleable peptide binding.Nat Commun2018
29545330Potent Immune Modulation by MEDI6383, an Engineered Human OX40 Ligand IgG4P Fc Fusion Protein.Mol Cancer Ther2018
29334373Prevention of tuberculosis in rhesus macaques by a cytomegalovirus-based vaccine.Nat Med2018
27759023MR1-restricted mucosal-associated invariant T (MAIT) cells respond to mycobacterial vaccination and infection in nonhuman primates.Mucosal Immunol2017
28428537Human Cytomegalovirus Induces Cellular and Humoral Virus-specific Immune Responses in Humanized BLT Mice.Sci Rep2017
29021601Novel vaccine vectors for HIV-1.Nat Rev Microbiol2017
28505602Unusual antigen presentation offers new insight into HIV vaccine design.Curr Opin Immunol2017
28636599Addendum: Immune clearance of highly pathogenic SIV infection.Nature2017
28734175CD8+ T cell programming by cytomegalovirus vectors: applications in prophylactic and therapeutic vaccination.Curr Opin Immunol2017
26797147Broadly targeted CD8⁺ T cell responses restricted by major histocompatibility complex E.Science2016
27703185Epigraph: A Vaccine Design Tool Applied to an HIV Therapeutic Vaccine and a Pan-Filovirus Vaccine.Sci Rep2016
27760342Antiviral CD8<sup>+</sup> T Cells Restricted by Human Leukocyte Antigen Class II Exist during Natural HIV Infection and Exhibit Clonal Expansion.Immunity2016
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Collaborators

Jeffrey D Lifson
Frederick National Laboratory
Co-authored papers 33
Afam A Okoye
Vaccine & Gene Therapy Institute, and Oregon National Primate Research Center
Co-authored papers 18
Jay A Nelson
Oregon Health and Science University
Co-authored papers 13
Byung Park
Oregon Health & Science University
Co-authored papers 11
Jacob D Estes
Vaccine and Gene Therapy Institute, Oregon Health & Science University
Co-authored papers 11
David I Watkins
Co-authored papers 10
Daniel N Streblow
Vaccine and Gene Therapy Institute, Oregon Health and Science University
Co-authored papers 7
Richard H Scheuermann
J. Craig Venter Institute
Co-authored papers 6
Holden T Maecker
Co-authored papers 6
David H O'Connor
Co-authored papers 6
Michael Gale
Center for Innate Immunity and Immune Disease, University of Washington
Co-authored papers 5
Craig N Kreklywich
Vaccine and Gene Therapy Institute, Oregon Health and Science University
Co-authored papers 5
Janko Nikolich-Zugich
University of Arizona Center on Aging, University of Arizona
Co-authored papers 5
Brandon F Keele
Co-authored papers 5
Steven G Deeks
University of California san francisco
Co-authored papers 5
Jason M Brenchley
National Institute of Allergy and Infectious Diseases, National Institutes of Health
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Francois Villinger
Co-authored papers 5
Bette Korber
Co-authored papers 4
Todd M Allen
Co-authored papers 4
Margaret Juliana McElrath
Co-authored papers 4
David C Montefiori
Co-authored papers 4
Benjamin Varco-Merth
Vaccine and Gene Therapy Institute and.
Co-authored papers 4
Patrizia Caposio
Vaccine and Gene Therapy Institute, Oregon Health & Science University
Co-authored papers 3
Michael B Brenner
Co-authored papers 3
Steven M Wolinsky
Northwestern University Feinberg School of Medicine
Co-authored papers 3
Adrian B McDermott
Co-authored papers 3
Meaghan H Hancock
Vaccine and Gene Therapy Institute, Oregon Health & Science University
Co-authored papers 3
Dan H Barouch
Co-authored papers 3
Michael Nekorchuk
Vaccine & Gene Therapy Institute, Oregon Health & Science University
Co-authored papers 3
Rafick-Pierre Sekaly
Pathology Advanced Translational Research Unit, Emory University School of Medicine
Co-authored papers 3
Release 1.2