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Author Details

Chen-Hsiang Yeang
Institute of Statistical Science
2001
41
15
Trey Ideker (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36812605An integrated analysis of the cancer genome atlas data discovers a hierarchical association structure across thirty three cancer types.PLOS Digit Health2022
35729235Cooperative stability renders protein complex formation more robust and controllable.Sci Rep2022
35665803Characterization of gene cluster heterogeneity in single-cell transcriptomic data within and across cancer types.Biol Open2022
33469951The C-degron pathway eliminates mislocalized proteins and products of deubiquitinating enzymes.EMBO J2021
34493766Genotypes of informative loci from 1000 Genomes data allude evolution and mixing of human populations.Sci Rep2021
32142644Population Histories of the United States Revealed through Fine-Scale Migration and Haplotype Analysis.Am J Hum Genet2020
31077681Modelling bistable tumour population dynamics to design effective treatment strategies.J Theor Biol2019
31437254Correction: Exploring candidate biological functions by Boolean Function Networks for Saccharomyces cerevisiae.PLoS One2019
30885118MGSEA - a multivariate Gene set enrichment analysis.BMC Bioinformatics2019
30061703Explaining cancer type specific mutations with transcriptomic and epigenomic features in normal tissues.Sci Rep2018
28837809Decomposing Oncogenic Transcriptional Signatures to Generate Maps of Divergent Cellular States.Cell Syst2017
28178267A quantitative model for the rate-limiting process of UGA alternative assignments to stop and selenocysteine codons.PLoS Comput Biol2017
28981547Exploring candidate biological functions by Boolean Function Networks for Saccharomyces cerevisiae.PLoS One2017
26786896Analysis of spatial-temporal gene expression patterns reveals dynamics and regionalization in developing mouse brain.Sci Rep2016
27770811Long range personalized cancer treatment strategies incorporating evolutionary dynamics.Biol Direct2016
27194416Detection of 22q11.2 microduplication by cell-free DNA screening and chromosomal microarray in fetus with multiple anomalies.Ultrasound Obstet Gynecol2016
26160836Putative effectors for prognosis in lung adenocarcinoma are ethnic and gender specific.Oncotarget2015
24700679Genome-wide normalized score: a novel algorithm to detect fetal trisomy 21 during non-invasive prenatal testing.Ultrasound Obstet Gynecol2014
29764056Nonstandard personalized medicine strategies for cancer may lead to improved patient outcomes.Per Med2014
24527393Suppression of the SOX2 neural effector gene by PRDM1 promotes human germ cell fate in embryonic stem cells.Stem Cell Reports2014
23303791Functional characterization of motif sequences under purifying selection.Nucleic Acids Res2013
23907387An integrative characterization of recurrent molecular aberrations in glioblastoma genomes.Nucleic Acids Res2013
22529953Genome-wide gene expression analysis implicates the immune response and lymphangiogenesis in the pathogenesis of fetal chylothorax.PLoS One2012
22936075Evolution of domain architectures and catalytic functions of enzymes in metabolic systems.Genome Biol Evol2012
22891318Impact of genetic dynamics and single-cell heterogeneity on development of nonstandard personalized medicine strategies for cancer.Proc Natl Acad Sci U S A2012
20737299Integration of metabolic reactions and gene regulation.Mol Biotechnol2011
22051105Deciphering causal and statistical relations of molecular aberrations and gene expressions in NCI-60 cell lines.BMC Syst Biol2011
20925909An integrated analysis of molecular aberrations in NCI-60 cell lines.BMC Bioinformatics2010
19209724Inferring disease-related pathways using a probabilistic epistasis model.Pac Symp Biocomput2009
19588110Integration of metabolic reactions and gene regulation.Methods Mol Biol2009
19180177A factor graph nested effects model to identify networks from genetic perturbations.PLoS Comput Biol2009
18434431Combinatorial patterns of somatic gene mutations in cancer.FASEB J2008
19204811Identifying coevolving partners from paralogous gene families.Evol Bioinform Online2008
17636042Detecting the coevolution of biosequences--an example of RNA interaction prediction.Mol Biol Evol2007
17983264Detecting coevolution in and among protein domains.PLoS Comput Biol2007
16597252Modeling the combinatorial functions of multiple transcription factors.J Comput Biol2006
16820044A joint model of regulatory and metabolic networks.BMC Bioinformatics2006
15998451Validation and refinement of gene-regulatory pathways on a network of physical interactions.Genome Biol2005
15285891Physical network models.J Comput Biol2004
11473023Molecular classification of multiple tumor types.Bioinformatics2001
11742071Multiclass cancer diagnosis using tumor gene expression signatures.Proc Natl Acad Sci U S A2001
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Collaborators

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Massachusetts Institute of Technology
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Vanderbilt-Ingram Cancer Center, Vanderbilt University
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university of california san diego
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University of California at Santa Cruz
Co-authored papers 2
Broad Institute of MIT and Harvard
Co-authored papers 2
Broad Institute
Co-authored papers 1
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Broad Institute of Harvard and MIT
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Broad Institute of MIT and Harvard, USA Dana-Farber Cancer Institute
Co-authored papers 1
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Broad Institute of Harvard and MIT
Co-authored papers 1
Broad Institute of MIT and Harvard
Co-authored papers 1
Massachusetts General Hospital
Co-authored papers 1
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University of California San Diego Health Moores Cancer Center.
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Janssen Research and Development LLC
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