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Author Details

Cindy Sander
UPMC Hillman Cancer Center
1997
51
27
Trey Ideker (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
35932099Multiple primary melanoma in association with other personal and familial cancers.Cancer Med2023
37857525Identification of tumor-intrinsic drivers of immune exclusion in acral melanoma.J Immunother Cancer2023
37662409Identification of tumor-intrinsic drivers of immune exclusion in acral melanoma.bioRxiv2023
37435077Expression of lymphoid structure-associated cytokine/chemokine gene transcripts in tumor and protein in serum are prognostic of melanoma patient outcomes.Front Immunol2023
37397389Metformin is associated with improved clinical outcomes in patients with melanoma: a retrospective, multi-institutional study.Front Oncol2023
36960318Development and Narrow Validation of Computer Vision Approach to Facilitate Assessment of Change in Pigmented Cutaneous Lesions.JID Innov2023
35316223Tim-3 mediates T cell trogocytosis to limit antitumor immunity.J Clin Invest2022
36356143TPP1 promoter mutations cooperate with TERT promoter mutations to lengthen telomeres in melanoma.Science2022
36291758Sentinel Lymph Node Gene Expression Signature Predicts Recurrence-Free Survival in Cutaneous Melanoma.Cancers (Basel)2022
35879777Co-expression of TNF receptors 1 and 2 on melanomas facilitates soluble TNF-induced resistance to MAPK pathway inhibitors.J Transl Med2022
35319783Poorer survival outcomes in patients with multiple versus single primary melanoma.Cancer2022
32557708Predicting Metastasis in Melanoma by Enumerating Circulating Tumor Cells Using Photoacoustic Flow Cytometry.Lasers Surg Med2021
33753453Neoadjuvant Pembrolizumab and High-Dose IFNα-2b in Resectable Regionally Advanced Melanoma.Clin Cancer Res2021
33170961Indoor tanning exposure in association with multiple primary melanoma.Cancer2021
34124690Activation of p38α stress-activated protein kinase drives the formation of the pre-metastatic niche in the lungs.Nat Cancer2020
30571927Neratinib and entinostat combine to rapidly reduce the expression of K-RAS, N-RAS, Gα<sub>q</sub> and Gα<sub>11</sub> and kill uveal melanoma cells.Cancer Biol Ther2019
30761123CD56<sup>dim</sup> CD16<sup>-</sup> Natural Killer Cell Profiling in Melanoma Patients Receiving a Cancer Vaccine and Interferon-α.Front Immunol2019
30721155Tumor cell oxidative metabolism as a barrier to PD-1 blockade immunotherapy in melanoma.JCI Insight2019
29219657The levels of mutant K-RAS and mutant N-RAS are rapidly reduced in a Beclin1 / ATG5 -dependent fashion by the irreversible ERBB1/2/4 inhibitor neratinib.Cancer Biol Ther2018
30046006CD226 opposes TIGIT to disrupt Tregs in melanoma.JCI Insight2018
30359157Phase Ib/II Study of Pembrolizumab and Pegylated-Interferon Alfa-2b in Advanced Melanoma.J Clin Oncol2018
29691233Evaluation of Biodistribution of Sulforaphane after Administration of Oral Broccoli Sprout Extract in Melanoma Patients with Multiple Atypical Nevi.Cancer Prev Res (Phila)2018
28923120High-dose interleukin-2 (HD IL-2) for advanced melanoma: a single center experience from the University of Pittsburgh Cancer Institute.J Immunother Cancer2017
28489678Safety and efficacy of the antiganglioside GD3 antibody ecromeximab (KW2871) combined with high-dose interferon-α2b in patients with metastatic melanoma.Melanoma Res2017
28146421The HDAC inhibitor AR42 interacts with pazopanib to kill trametinib/dabrafenib-resistant melanoma cells in vitro and in vivo.Oncotarget2017
28825947A unique gene expression signature is significantly differentially expressed in tumor-positive or tumor-negative sentinel lymph nodes in patients with melanoma.Melanoma Res2017
28552348Interferon-γ Drives T<sub>reg</sub> Fragility to Promote Anti-tumor Immunity.Cell2017
28344862Expression profiles of immune-related genes are associated with neoadjuvant ipilimumab clinical benefit.Oncoimmunology2016
25728676Transcriptional repression of IFNβ1 by ATF2 confers melanoma resistance to therapy.Oncogene2015
26380086Baseline circulating IL-17 predicts toxicity while TGF-β1 and IL-10 are prognostic of relapse in ipilimumab neoadjuvant therapy of melanoma.J Immunother Cancer2015
26419843Tumor associated PD-L1 expression pattern in microscopically tumor positive sentinel lymph nodes in patients with melanoma.J Transl Med2015
26192408Pro-Inflammatory Cytokines Predict Relapse-Free Survival after One Month of Interferon-α but Not Observation in Intermediate Risk Melanoma Patients.PLoS One2015
25866972TIGIT and PD-1 impair tumor antigen-specific CD8⁺ T cells in melanoma patients.J Clin Invest2015
25720800IL10 and PD-1 Cooperate to Limit the Activity of Tumor-Specific CD8+ T Cells.Cancer Res2015
24498358Immune monitoring of the circulation and the tumor microenvironment in patients with regionally advanced melanoma receiving neoadjuvant ipilimumab.PLoS One2014
24509407Serologic evidence of autoimmunity in E2696 and E1694 patients with high-risk melanoma treated with adjuvant interferon alfa.Melanoma Res2014
24343228PD-1 and Tim-3 regulate the expansion of tumor antigen-specific CD8⁺ T cells induced by melanoma vaccines.Cancer Res2014
24457057A four-marker signature of TNF-RII, TGF-α, TIMP-1 and CRP is prognostic of worse survival in high-risk surgically resected melanoma.J Transl Med2014
22184371Safety and efficacy of combination immunotherapy with interferon alfa-2b and tremelimumab in patients with stage IV melanoma.J Clin Oncol2012
22912665Mitochondrial respiration--an important therapeutic target in melanoma.PLoS One2012
22495394Safety and immunogenicity of vaccination with MART-1 (26-35, 27L), gp100 (209-217, 210M), and tyrosinase (368-376, 370D) in adjuvant with PF-3512676 and GM-CSF in metastatic melanoma.J Immunother2012
22210094Pitfalls in retrospective analyses of biomarkers: a case study with metastatic melanoma patients.J Immunol Methods2012
22205715CD8(+) T cells specific for tumor antigens can be rendered dysfunctional by the tumor microenvironment through upregulation of the inhibitory receptors BTLA and PD-1.Cancer Res2012
20445352Pharmacodynamic (phase 0) study using etaracizumab in advanced melanoma.J Immunother2010
20819923Upregulation of Tim-3 and PD-1 expression is associated with tumor antigen-specific CD8+ T cell dysfunction in melanoma patients.J Exp Med2010
19047287Prognostic significance of serum S100B protein in high-risk surgically resected melanoma patients participating in Intergroup Trial ECOG 1694.J Clin Oncol2009
19380770PD-1 is a regulator of NY-ESO-1-specific CD8+ T cell expansion in melanoma patients.J Immunol2009
19228745Immunogenicity and antitumor effects of vaccination with peptide vaccine+/-granulocyte-monocyte colony-stimulating factor and/or IFN-alpha2b in advanced metastatic melanoma: Eastern Cooperative Oncology Group Phase II Trial E1696.Clin Cancer Res2009
18779741Immunization with analog peptide in combination with CpG and montanide expands tumor antigen-specific CD8+ T cells in melanoma patients.J Immunother2008
16908595Mitotic arrest, apoptosis, and sensitization to chemotherapy of melanomas by methionine deprivation stress.Mol Cancer Res2006
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Collaborators

UPMC Hillman Cancer Center
Co-authored papers 47
MD Anderson Cancer Center
Co-authored papers 6
Yale School of Medicine
Co-authored papers 2
Center for Molecular Imaging, University of Pittsburgh School of Medicine
Co-authored papers 2
University Hospital Zurich
Co-authored papers 1
National Centre for Asbestos Related Diseases, University of Western Australia
Co-authored papers 1
Sanford Burnham Prebys Medical Discovery Institute
Co-authored papers 1
Moffitt Cancer Center
Co-authored papers 1
Sanford Burnham Prebys Medical Discovery Institute
Co-authored papers 1
Pfizer Inc.
Co-authored papers 1
Cancer Center, Sanford Burnham Prebys Medical Discovery Institute
Co-authored papers 1
Co-authored papers 1
Departments of Pharmaceutical Sciences.
Co-authored papers 1
Amgen Inc.
Co-authored papers 1
University of Pittsburgh Medical Center
Co-authored papers 1
University of Colorado Anschutz Medical Campus
Co-authored papers 1
UPMC-Hillman Cancer Center, University of Pittsburgh
Co-authored papers 1
Departments of Oncology. St. Jude Children's Research Hospital
Co-authored papers 1
West Virginia University School of Medicine
Co-authored papers 1
Sanford Burnham Prebys Medical Discovery Institute
Co-authored papers 1
University Hospital of Zurich
Co-authored papers 1
Saint John's Cancer Institute at Saint John's Health Center
Co-authored papers 1
Princess Margaret Cancer Centre, University Health Network
Co-authored papers 1
Cancer Center, Sanford Burnham Prebys Medical Discovery Institute
Co-authored papers 1
Pfizer Inc.
Co-authored papers 1
Case Western Reserve University School of Medicine
Co-authored papers 1
The Henry M. Jackson Foundation for the Advancement of Military Medicine
Co-authored papers 1
University of Pittsburgh
Co-authored papers 1
Princess Margaret Cancer Centre, Ontario Cancer Institute, University Health Network
Co-authored papers 1
University of California San Diego
Co-authored papers 1