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Author Details
Full Name
Danica Galoni?? Fujimori
Affiliation
University of California San Francisco
ORCID
Career Start Year
2002
Papers
60
H Index
29
Expertise
CM4AI Collaborator
Trey Ideker (CM4AI)
PMID
Paper Title
Journal Title
Published Year
36495919
Chromatin Sensing by the Auxiliary Domains of KDM5C Regulates Its Demethylase Activity and Is Disrupted by X-linked Intellectual Disability Mutations.
J Mol Biol
2023
38014974
Angucyclinones rescue PhLOPS<sub>A</sub> antibiotic activity by inhibiting Cfr-dependent antibiotic resistance.
mBio
2023
37832177
Recent developments in catalysis and inhibition of the Jumonji histone demethylases.
Curr Opin Struct Biol
2023
36948085
Chemical tools targeting readers of lysine methylation.
Curr Opin Chem Biol
2023
37294077
Structure-Based Discovery of Inhibitors of the SARS-CoV-2 Nsp14 N7-Methyltransferase.
J Med Chem
2023
35165456
Structural basis for context-specific inhibition of translation by oxazolidinone antibiotics.
Nat Struct Mol Biol
2022
35839775
Viral E protein neutralizes BET protein-mediated post-entry antagonism of SARS-CoV-2.
Cell Rep
2022
35756531
Covalent labeling of a chromatin reader domain using proximity-reactive cyclic peptides.
Chem Sci
2022
36371847
Editorial overview: Catalysis and regulation: The chemistry of catalysis.
Curr Opin Struct Biol
2022
35866897
First-in-Class Allosteric Inhibitors of DNMT3A Disrupt Protein-Protein Interactions and Induce Acute Myeloid Leukemia Cell Differentiation.
J Med Chem
2022
35985635
Catching BETs by viruses.
Biochim Biophys Acta Gene Regul Mech
2022
35015630
Directed evolution of the rRNA methylating enzyme Cfr reveals molecular basis of antibiotic resistance.
Elife
2022
33314922
Exploring the Ligand Preferences of the PHD1 Domain of Histone Demethylase KDM5A Reveals Tolerance for Modifications of the Q5 Residue of Histone 3.
ACS Chem Biol
2021
34085241
miCLIP-MaPseq Identifies Substrates of Radical SAM RNA-Methylating Enzyme Using Mechanistic Cross-Linking and Mismatch Profiling.
Methods Mol Biol
2021
32353859
A SARS-CoV-2 protein interaction map reveals targets for drug repurposing.
Nature
2020
31989172
Assessment of the nucleotide modifications in the high-resolution cryo-electron microscopy structure of the Escherichia coli 50S subunit.
Nucleic Acids Res
2020
31985200
Extended Recognition of the Histone H3 Tail by Histone Demethylase KDM5A.
Biochemistry
2020
32758979
Domain cross-talk in regulation of histone modifications: Molecular mechanisms and targeting opportunities.
Curr Opin Chem Biol
2020
32475402
Dissecting contributions of catalytic and reader domains in regulation of histone demethylation.
Methods Enzymol
2020
30626866
Histone H3 binding to the PHD1 domain of histone demethylase KDM5A enables active site remodeling.
Nat Commun
2019
31685464
<i>cfr</i>(B), <i>cfr</i>(C), and a New <i>cfr</i>-Like Gene, <i>cfr</i>(E), in Clostridium difficile Strains Recovered across Latin America.
Antimicrob Agents Chemother
2019
29782154
miCLIP-MaPseq, a Substrate Identification Approach for Radical SAM RNA Methylating Enzymes.
J Am Chem Soc
2018
29059606
Mutations in RNA methylating enzymes in disease.
Curr Opin Chem Biol
2017
26699912
Docking and Linking of Fragments To Discover Jumonji Histone Demethylase Inhibitors.
J Med Chem
2016
27902775
Determinants of tRNA Recognition by the Radical SAM Enzyme RlmN.
PLoS One
2016
27614207
Editorial overview: Chemical genetics and epigenetics.
Curr Opin Chem Biol
2016
27357682
Htm1p-Pdi1p is a folding-sensitive mannosidase that marks N-glycoproteins for ER-associated protein degradation.
Proc Natl Acad Sci U S A
2016
27496281
Antibiotic resistance evolved via inactivation of a ribosomal RNA methylating enzyme.
Nucleic Acids Res
2016
26747609
Opposing Chromatin Signals Direct and Regulate the Activity of Lysine Demethylase 4C (KDM4C).
J Biol Chem
2016
25533783
Product binding enforces the genomic specificity of a yeast polycomb repressive complex.
Cell
2015
26323614
Improved Peak Detection and Deconvolution of Native Electrospray Mass Spectra from Large Protein Complexes.
J Am Soc Mass Spectrom
2015
26496625
Functional coupling between writers, erasers and readers of histone and DNA methylation.
Curr Opin Struct Biol
2015
26253978
Radical SAM-Mediated Methylation of Ribosomal RNA.
Methods Enzymol
2015
25686748
Histone demethylase KDM5A is regulated by its reader domain through a positive-feedback mechanism.
Nat Commun
2015
23398247
Site-specific and regiospecific installation of methylarginine analogues into recombinant histones and insights into effector protein binding.
J Am Chem Soc
2013
23835516
Radical SAM-mediated methylation reactions.
Curr Opin Chem Biol
2013
23601638
Reconstitution of nucleosome demethylation and catalytic properties of a Jumonji histone demethylase.
Chem Biol
2013
22208312
The chemistry of peptidyltransferase center-targeted antibiotics: enzymatic resistance and approaches to countering resistance.
ACS Chem Biol
2012
23088750
Covalent intermediate in the catalytic mechanism of the radical S-adenosyl-L-methionine methyl synthase RlmN trapped by mutagenesis.
J Am Chem Soc
2012
23085277
Protein and nucleic acid methylating enzymes: mechanisms and regulation.
Curr Opin Chem Biol
2012
21368151
RNA methylation by radical SAM enzymes RlmN and Cfr proceeds via methylene transfer and hydride shift.
Proc Natl Acad Sci U S A
2011
20184321
RlmN and Cfr are radical SAM enzymes involved in methylation of ribosomal RNA.
J Am Chem Soc
2010
21168760
A novel enzymatic rearrangement.
Chem Biol
2010
19281171
Structural analysis of an open active site conformation of nonheme iron halogenase CytC3.
J Am Chem Soc
2009
19295524
Hypoxia sensing goes gauche.
Nat Chem Biol
2009
18291314
Halogenation strategies in natural product biosynthesis.
Chem Biol
2008
17209546
Characterization of the aminocarboxycyclopropane-forming enzyme CmaC.
Biochemistry
2007
17967013
CD and MCD of CytC3 and taurine dioxygenase: role of the facial triad in alpha-KG-dependent oxygenases.
J Am Chem Soc
2007
17940045
Cloning and characterization of the biosynthetic gene cluster for kutznerides.
Proc Natl Acad Sci U S A
2007
17939667
Spectroscopic evidence for a high-spin Br-Fe(IV)-oxo intermediate in the alpha-ketoglutarate-dependent halogenase CytC3 from Streptomyces.
J Am Chem Soc
2007
1 - 50 of 60
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row(s) 1 - 30 of 30
Collaborators
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Co-authored papers
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University of California san francisco
Co-authored papers
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Department of Pharmaceutical Chemistry, University of California San Francisco
Co-authored papers
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Co-authored papers
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Co-authored papers
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Co-authored papers
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Co-authored papers
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Co-authored papers
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Philip J Robinson
College of Medical Veterinary and Life Sciences, University of Glasgow
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1
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Northwestern University
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Management and Science University
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1
Hannes Braberg
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Yiming Cai
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Rahul K Suryawanshi
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Alan D Frankel
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