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Author Details

Fiona E Harrison
Vanderbilt University Medical Center
2006
61
30
PMIDPaper TitleJournal TitlePublished Year
36243287Altered EEG, disrupted hippocampal long-term potentiation and neurobehavioral deficits implicate a delirium-like state in a mouse model of sepsis.Brain Behav Immun2023
36853612Association of Vitamin C, Thiamine, and Hydrocortisone Infusion With Long-term Cognitive, Psychological, and Functional Outcomes in Sepsis Survivors: A Secondary Analysis of the Vitamin C, Thiamine, and Steroids in Sepsis Randomized Clinical Trial.JAMA Netw Open2023
35063467Manganese-induced hyperactivity and dopaminergic dysfunction depend on age, sex and YAC128 genotype.Pharmacol Biochem Behav2022
35745661Longitudinal Consumption of Ergothioneine Reduces Oxidative Stress and Amyloid Plaques and Restores Glucose Metabolism in the 5XFAD Mouse Model of Alzheimer's Disease.Pharmaceuticals (Basel)2022
36069787Epigenetic remodeling by vitamin C potentiates plasma cell differentiation.Elife2022
33830406Serotonin Transporter Ala276 Mouse: Novel Model to Assess the Neurochemical and Behavioral Impact of Thr276 Phosphorylation In Vivo.Neurochem Res2022
35100442Improved synthesis of an ergothioneine PET radioligand for imaging oxidative stress in Alzheimer's disease.FEBS Lett2022
33008490Effects of Acrylic Tunnel Enrichment on Anxiety-Like Behavior, Neurogenesis, and Physiology of C57BL/6J Mice.J Am Assoc Lab Anim Sci2021
33544780Decreased content of ascorbic acid (vitamin C) in the brain of knockout mouse models of Na+,K+-ATPase-related neurologic disorders.PLoS One2021
34382806Targeted and Untargeted Mass Spectrometry Reveals the Impact of High-Fat Diet on Peripheral Amino Acid Regulation in a Mouse Model of Alzheimer's Disease.J Proteome Res2021
34543681YAC128 mouse model of Huntington disease is protected against subtle chronic manganese (Mn)-induced behavioral and neuropathological changes.Neurotoxicology2021
34450329Altered synaptic glutamate homeostasis contributes to cognitive decline in young APP/PSEN1 mice.Neurobiol Dis2021
34531467A novel antioxidant ergothioneine PET radioligand for in vivo imaging applications.Sci Rep2021
33935841Autism-Associated Variant in the SLC6A3 Gene Alters the Oral Microbiome and Metabolism in a Murine Model.Front Psychiatry2021
32797675Ascorbate deficiency decreases dopamine release in gulo[-/-] and APP/PSEN1 mice.J Neurochem2021
32567221Vitamin C is a source of oxoaldehyde and glycative stress in age-related cataract and neurodegenerative diseases.Aging Cell2020
32421118Huntington's disease genotype suppresses global manganese-responsive processes in pre-manifest and manifest YAC128 mice.Metallomics2020
32188696Brain manganese and the balance between essential roles and neurotoxicity.J Biol Chem2020
32224930A Cecal Slurry Mouse Model of Sepsis Leads to Acute Consumption of Vitamin C in the Brain.Nutrients2020
31094705Autism-linked dopamine transporter mutation alters striatal dopamine neurotransmission and dopamine-dependent behaviors.J Clin Invest2019
31499164Behavioral analyses of animal models of intellectual and developmental disabilities.Neurobiol Learn Mem2019
31546716New Insights on the Role of Manganese in Alzheimer's Disease and Parkinson's Disease.Int J Environ Res Public Health2019
31364379Cell-free hemoglobin augments acute kidney injury during experimental sepsis.Am J Physiol Renal Physiol2019
30922937Impaired amygdala-based learning and decreased anxiety in a murine model of pseudohypoparathyroidism type 1A.Behav Brain Res2019
29253591Markers of oxidative damage to lipids, nucleic acids and proteins and antioxidant enzymes activities in Alzheimer's disease brain: A meta-analysis in human pathological specimens.Free Radic Biol Med2018
29987201Oxidative Stress Levels in the Brain Are Determined by Post-Mortem Interval and Ante-Mortem Vitamin C State but Not Alzheimer's Disease Status.Nutrients2018
30172223Altered glutamate clearance in ascorbate deficient mice increases seizure susceptibility and contributes to cognitive impairment in APP/PSEN1 mice.Neurobiol Aging2018
30367086Antioxidants prevent inflammation and preserve the optic projection and visual function in experimental neurotrauma.Cell Death Dis2018
29618789Altered DNA repair; an early pathogenic pathway in Alzheimer's disease and obesity.Sci Rep2018
28863942Mitochondrial dysfunction in the APP/PSEN1 mouse model of Alzheimer's disease and a novel protective role for ascorbate.Free Radic Biol Med2017
28108292Reversal of high fat diet-induced obesity improves glucose tolerance, inflammatory response, β-amyloid accumulation and cognitive decline in the APP/PSEN1 mouse model of Alzheimer's disease.Neurobiol Dis2017
28220990Oxidative stress, serotonergic changes and decreased ultrasonic vocalizations in a mouse model of Smith-Lemli-Opitz syndrome.Genes Brain Behav2017
25535150Vitamin C facilitates dopamine neuron differentiation in fetal midbrain through TET1- and JMJD3-dependent epigenetic control manner.Stem Cells2015
26340637Shared Neuropathological Characteristics of Obesity, Type 2 Diabetes and Alzheimer's Disease: Impacts on Cognitive Decline.Nutrients2015
25642732Vitamin C deficiency in the brain impairs cognition, increases amyloid accumulation and deposition, and oxidative stress in APP/PSEN1 and normally aging mice.ACS Chem Neurosci2015
25616451Low brain ascorbic acid increases susceptibility to seizures in mouse models of decreased brain ascorbic acid transport and Alzheimer's disease.Epilepsy Res2015
25818006Differential proteomic and behavioral effects of long-term voluntary exercise in wild-type and APP-overexpressing transgenics.Neurobiol Dis2015
23896203Antioxidant supplementation ameliorates molecular deficits in Smith-Lemli-Opitz syndrome.Biol Psychiatry2014
24763117Ascorbic acid and the brain: rationale for the use against cognitive decline.Nutrients2014
24508240Intravenous ascorbate improves spatial memory in middle-aged APP/PSEN1 and wild type mice.Behav Brain Res2014
23106783Behavioral and monoamine changes following severe vitamin C deficiency.J Neurochem2013
23581713Role of vitamin C in the function of the vascular endothelium.Antioxid Redox Signal2013
23541496Behavioral and serotonergic response changes in the Dhcr7-HET mouse model of Smith-Lemli-Opitz syndrome.Pharmacol Biochem Behav2013
23321552Combined vitamin C and E deficiency induces motor defects in gulo(-/-)/SVCT2(+/-) mice.Nutr Neurosci2013
22366772A critical review of vitamin C for the prevention of age-related cognitive decline and Alzheimer's disease.J Alzheimers Dis2012
24660109Vitamin C activation of the biosynthesis of epoxyeicosatrienoic acids.Adv Biosci Biotechnol2012
21709376Treatment with a γ-ketoaldehyde scavenger prevents working memory deficits in hApoE4 mice.J Alzheimers Dis2011
22001929Differential regulation of the ascorbic acid transporter SVCT2 during development and in response to ascorbic acid depletion.Biochem Biophys Res Commun2011
19941887Vitamin C deficiency increases basal exploratory activity but decreases scopolamine-induced activity in APP/PSEN1 transgenic mice.Pharmacol Biochem Behav2010
20541602Low vitamin C and increased oxidative stress and cell death in mice that lack the sodium-dependent vitamin C transporter SVCT2.Free Radic Biol Med2010
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Collaborators

Vanderbilt University Medical Center
Co-authored papers 4
Vanderbilt University Medical Center
Co-authored papers 2
Emory University
Co-authored papers 1
Vanderbilt University Medical Center
Co-authored papers 1
Vanderbilt University Medical Center
Co-authored papers 1
Vanderbilt University Medical Center
Co-authored papers 1
Duke University
Co-authored papers 1
Stanford University
Co-authored papers 1
Boston Children's Hospital, Harvard Medical School
Co-authored papers 1
Vanderbilt University Medical Center
Co-authored papers 1
College of Sciences, The University of Texas at San Antonio
Co-authored papers 1
Vanderbilt University Medical Center
Co-authored papers 1
Vanderbilt University Medical Center
Co-authored papers 1
Vanderbilt University Medical Center
Co-authored papers 1
Co-authored papers 1
Vanderbilt University Medical Center
Co-authored papers 1