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Author Details
Full Name
William R Pearson
Affiliation
University of Virginia
ORCID
Career Start Year
1974
Papers
92
H Index
43
Expertise
CM4AI Collaborator
PMID
Paper Title
Journal Title
Published Year
36482890
Comparison of detection methods and genome quality when quantifying nuclear mitochondrial insertions in vertebrate genomes.
Front Genet
2022
29870542
Bioinformatics core competencies for undergraduate life sciences education.
PLoS One
2018
27923999
Query-seeded iterative sequence similarity searching improves selectivity 5-20-fold.
Nucleic Acids Res
2017
28902397
Using SQL Databases for Sequence Similarity Searching and Analysis.
Curr Protoc Bioinformatics
2017
27010337
Finding Protein and Nucleotide Similarities with FASTA.
Curr Protoc Bioinformatics
2016
27175996
Applying, Evaluating and Refining Bioinformatics Core Competencies (An Update from the Curriculum Task Force of ISCB's Education Committee).
PLoS Comput Biol
2016
25976240
Most partial domains in proteins are alignment and annotation artifacts.
Genome Biol
2015
26334923
Protein Function Prediction: Problems and Pitfalls.
Curr Protoc Bioinformatics
2015
24170396
BLAST and FASTA similarity searching for multiple sequence alignment.
Methods Mol Biol
2014
24319146
The Catalytic Site Atlas 2.0: cataloging catalytic sites and residues identified in enzymes.
Nucleic Acids Res
2014
23749753
An introduction to sequence similarity ("homology") searching.
Curr Protoc Bioinformatics
2013
24509512
Selecting the Right Similarity-Scoring Matrix.
Curr Protoc Bioinformatics
2013
23995390
Adjusting scoring matrices to correct overextended alignments.
Bioinformatics
2013
22058127
MACiE: exploring the diversity of biochemical reactions.
Nucleic Acids Res
2012
22539666
PSI-Search: iterative HOE-reduced profile SSEARCH searching.
Bioinformatics
2012
20064877
Homologous over-extension: a challenge for iterative similarity searches.
Nucleic Acids Res
2010
20693322
RefProtDom: a protein database with improved domain boundaries and homology relationships.
Bioinformatics
2010
20307279
Improving pairwise sequence alignment accuracy using near-optimal protein sequence alignments.
BMC Bioinformatics
2010
19948773
Globally, unrelated protein sequences appear random.
Bioinformatics
2010
16891377
Exploring the relationship between sequence similarity and accurate phylogenetic trees.
Mol Biol Evol
2006
15919194
The limits of protein sequence comparison?
Curr Opin Struct Biol
2005
16399387
Phylogenies of glutathione transferase families.
Methods Enzymol
2005
16399376
Nomenclature for mammalian soluble glutathione transferases.
Methods Enzymol
2005
14978311
Sensitivity and selectivity in protein structure comparison.
Protein Sci
2004
18428739
Using relational databases for improved sequence similarity searching and large-scale genomic analyses.
Curr Protoc Bioinformatics
2004
18428723
Finding protein and nucleotide similarities with FASTA.
Curr Protoc Bioinformatics
2004
15510150
The genome of Cryptosporidium hominis.
Nature
2004
14751975
Visualization of near-optimal sequence alignments.
Bioinformatics
2004
12486119
Identification of residues in glutathione transferase capable of driving functional diversification in evolution. A novel approach to protein redesign.
J Biol Chem
2003
12824437
CRP: Cleavage of Radiolabeled Phosphoproteins.
Nucleic Acids Res
2003
12038961
Identification and characterization of GSTT3, a third murine Theta class glutathione transferase.
Biochem J
2002
12427470
Entamoeba histolytica: sequence conservation of the Gal/GalNAc lectin from clinical isolates.
Exp Parasitol
2002
12424122
Empirical determination of effective gap penalties for sequence comparison.
Bioinformatics
2002
12096132
Getting more from less: algorithms for rapid protein identification with multiple short peptide sequences.
Mol Cell Proteomics
2002
12096113
A strategy for the rapid identification of phosphorylation sites in the phosphoproteome.
Mol Cell Proteomics
2002
11590093
Training for bioinformatics and computational biology.
Bioinformatics
2001
10547837
Flexible sequence similarity searching with the FASTA3 program package.
Methods Mol Biol
2000
9854036
Gene structure, expression and chromosomal localization of murine theta class glutathione transferase mGSTT1-1.
Biochem J
1999
10368958
Generalized neighbor-joining: more reliable phylogenetic tree reconstruction.
Mol Biol Evol
1999
10452901
Evolution of protein sequences and structures.
J Mol Biol
1999
9882431
Distinctive structure of the human GSTM3 gene-inverted orientation relative to the mu class glutathione transferase gene cluster.
Arch Biochem Biophys
1999
10207159
Panning for genes--A visual strategy for identifying novel gene orthologs and paralogs.
Genome Res
1999
9733729
Rapid identification of protein phosphatase 1-binding proteins by mixed peptide sequencing and data base searching. Characterization of a novel holoenzymic form of protein phosphatase 1.
J Biol Chem
1998
9452477
Characterization of the human class Mu glutathione S-transferase gene cluster and the GSTM1 deletion.
J Biol Chem
1998
9514730
Empirical statistical estimates for sequence similarity searches.
J Mol Biol
1998
9403055
Comparison of DNA sequences with protein sequences.
Genomics
1997
9283747
Identifying distantly related protein sequences.
Comput Appl Biosci
1997
9278064
Aligning a DNA sequence with a protein sequence.
J Comput Biol
1997
8743688
Effective protein sequence comparison.
Methods Enzymol
1996
7584448
A new approach to primer selection in polymerase chain reaction experiments.
Proc Int Conf Intell Syst Mol Biol
1995
1 - 50 of 92
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