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Author Details

Gary D Bader
University of Toronto
2000
257
88
Trey Ideker (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36645249Cytoscape.js 2023 update: a graph theory library for visualization and analysis.Bioinformatics2023
38026201A rat liver cell atlas reveals intrahepatic myeloid heterogeneity.iScience2023
37551982Fate Specification of GFAP-Negative Primitive Neural Stem Cells and Their Progeny at Clonal Resolution.Stem Cells Dev2023
37503083Cell networks in the mouse liver during partial hepatectomy.bioRxiv2023
37106565Multi-scale systems genomics analysis predicts pathways, cell types, and drug targets involved in normative variation in peri-adolescent human cognition.Cereb Cortex2023
37463901Distinct shared and compartment-enriched oncogenic networks drive primary versus metastatic breast cancer.Nat Commun2023
37000033Genotyping SARS-CoV-2 Variants Using Ratiometric Nucleic Acid Barcode Panels.Anal Chem2023
37164978Multiplatform molecular profiling uncovers two subgroups of malignant peripheral nerve sheath tumors with distinct therapeutic vulnerabilities.Nat Commun2023
34788843The reactome pathway knowledgebase 2022.Nucleic Acids Res2022
35668135The metabolic enzyme hexokinase 2 localizes to the nucleus in AML and normal haematopoietic stem and progenitor cells to maintain stemness.Nat Cell Biol2022
35639948PLAG1 dampens protein synthesis to promote human hematopoietic stem cell self-renewal.Blood2022
35789175Comprehensive multi-cohort transcriptional meta-analysis of muscle diseases identifies a signature of disease severity.Sci Rep2022
35662469OpenPIP: An Open-source Platform for Hosting, Visualizing and Analyzing Protein Interaction Data.J Mol Biol2022
36408415Neurons and glial cells acquire a senescent signature after repeated mild traumatic brain injury in a sex-dependent manner.Front Neurosci2022
36496458Single-cell profiling of healthy human kidney reveals features of sex-based transcriptional programs and tissue-specific immunity.Nat Commun2022
36417873Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.Cell Rep2022
36108220Loss of Epigenetic Regulation Disrupts Lineage Integrity, Induces Aberrant Alveogenesis, and Promotes Breast Cancer.Cancer Discov2022
36055193Modeling human multi-lineage heart field development with pluripotent stem cells.Cell Stem Cell2022
36324805A single-nucleus and spatial transcriptomic atlas of the COVID-19 liver reveals topological, functional, and regenerative organ disruption in patients.bioRxiv2022
36008091Unraveling the Complexity of Liver Disease One Cell at a Time.Semin Liver Dis2022
35027446A Shared Transcriptional Identity for Forebrain and Dentate Gyrus Neural Stem Cells from Embryogenesis to Adulthood.eNeuro2022
35023164Hypophosphorylated pRb knock-in mice exhibit hallmarks of aging and vitamin C-preventable diabetes.EMBO J2022
35263585Identification of the global miR-130a targetome reveals a role for TBL1XR1 in hematopoietic stem cell self-renewal and t(8;21) AML.Cell Rep2022
34792289Single-Cell, Single-Nucleus, and Spatial RNA Sequencing of the Human Liver Identifies Cholangiocyte and Mesenchymal Heterogeneity.Hepatol Commun2022
33458693Sphingosine-1-phosphate receptor 3 potentiates inflammatory programs in normal and leukemia stem cells to promote differentiation.Blood Cancer Discov2021
33741928The transcriptional landscape of Shh medulloblastoma.Nat Commun2021
33594052Biological and therapeutic implications of a unique subtype of NPM1 mutated AML.Nat Commun2021
33758926SBGN Bricks Ontology as a tool to describe recurring concepts in molecular networks.Brief Bioinform2021
33758253Distinct DNA methylation patterns associated with treatment resistance in metastatic castration resistant prostate cancer.Sci Rep2021
33579912PRMT5 inhibition disrupts splicing and stemness in glioblastoma.Nat Commun2021
34860157Author-sourced capture of pathway knowledge in computable form using Biofactoid.Elife2021
34912541scNetViz: from single cells to networks using Cytoscape.F1000Res2021
35122077Gradient of Developmental and Injury Response transcriptional states defines functional vulnerabilities underpinning glioblastoma heterogeneity.Nat Cancer2021
34878832Temporal profiling of therapy resistance in human medulloblastoma identifies novel targetable drivers of recurrence.Sci Adv2021
34433969A clinically applicable integrative molecular classification of meningiomas.Nature2021
34651637A microfluidic platform enables comprehensive gene expression profiling of mouse retinal stem cells.Lab Chip2021
34039977Generation of mature compact ventricular cardiomyocytes from human pluripotent stem cells.Nat Commun2021
34212855Control of tissue development and cell diversity by cell cycle-dependent transcriptional filtering.Elife2021
34293334Nicotinamide phosphoribosyltransferase inhibitors selectively induce apoptosis of AML stem cells by disrupting lipid homeostasis.Cell Stem Cell2021
34031612Tutorial: guidelines for annotating single-cell transcriptomic maps using automated and manual methods.Nat Protoc2021
34110166Surveilling and Tracking COVID-19 Patients Using a Portable Quantum Dot Smartphone Device.Nano Lett2021
31218364Towards reliable named entity recognition in the biomedical domain.Bioinformatics2020
31647099Pathway Commons 2019 Update: integration, analysis and exploration of pathway data.Nucleic Acids Res2020
32060066Potential therapeutic targets for lung repair during human <i>ex vivo</i> lung perfusion.Eur Respir J2020
32086311Relapse-Fated Latent Diagnosis Subclones in Acute B Lineage Leukemia Are Drug Tolerant and Possess Distinct Metabolic Programs.Cancer Discov2020
31949161A network analysis to identify mediators of germline-driven differences in breast cancer prognosis.Nat Commun2020
33438817Large-scale survey and database of high affinity ligands for peptide recognition modules.Mol Syst Biol2020
33147339CD200 expression marks leukemia stem cells in human AML.Blood Adv2020
32859895Wnt activation as a therapeutic strategy in medulloblastoma.Nat Commun2020
32968282Functional genomic landscape of cancer-intrinsic evasion of killing by T cells.Nature2020
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Collaborators

University of Toronto
Co-authored papers 31
Ontario Institute for Cancer Research
Co-authored papers 23
Broad Institute of MIT and Harvard
Co-authored papers 17
The Hospital for Sick Children
Co-authored papers 17
The Hospital for Sick Children, University of Toronto
Co-authored papers 16
Princess Margaret Cancer Centre, University Health Network
Co-authored papers 16
University of Toronto
Co-authored papers 15
National University of Singapore
Co-authored papers 14
School of Pharmacy, University of Waterloo
Co-authored papers 12
Sloan Kettering Institute
Co-authored papers 12
and Clinical Immunology, Heinrich Heine University, University Hospital Dusseldorf
Co-authored papers 11
Princess Margaret Cancer Centre
Co-authored papers 11
Institut Curie, PSL Research University
Co-authored papers 10
Princess Margaret Cancer Research Centre
Co-authored papers 10
Institute of Pathology, University Hospital Heidelberg
Co-authored papers 9
Institute for Research in Immunology and Cancer (IRIC), Universite de Montreal
Co-authored papers 9
Princess Margaret Cancer Centre
Co-authored papers 9
McGill University Health Centre (MUHC), Montreal Children's Hospital (MCH)
Co-authored papers 9
Boston University School of Medicine, Boston University
Co-authored papers 9
University of Toronto
Co-authored papers 9
Hospital for Sick Children
Co-authored papers 9
Hopp Children's Cancer Center Heidelberg (KiTZ)
Co-authored papers 9
Princess Margaret Cancer Centre
Co-authored papers 9
The Hospital for Sick Children
Co-authored papers 9
Hospital for Sick Children
Co-authored papers 8
University of Toronto
Co-authored papers 8
The Hospital for Sick Children
Co-authored papers 8
Hopp Children's Cancer Center Heidelberg (KiTZ)
Co-authored papers 8
Hopp Children's Cancer Center (KiTZ)
Co-authored papers 8
Co-authored papers 8