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Author Details

Gregg E Homanics
University of Pittsburgh School of Medicine Pittsburgh Pennsylvania USA.
1988
191
55
PMIDPaper TitleJournal TitlePublished Year
37398055A marker chromosome in psychosis identifies glycine decarboxylase (GLDC) as a novel regulator of neuronal and synaptic function in the hippocampus.bioRxiv2023
37614242Bridging the rodent to human translational gap: Marmosets as model systems for the study of Alzheimer's disease.Alzheimers Dement (N Y)2023
36161942G protein-biased GPR3 signaling ameliorates amyloid pathology in a preclinical Alzheimer's disease mouse model.Proc Natl Acad Sci U S A2022
36405628Murine model of triosephosphate isomerase deficiency with anemia and severe neuromuscular dysfunction.Curr Res Neurobiol2022
36908580Hippocampal ceRNA networks from chronic intermittent ethanol vapor-exposed male mice and functional analysis of top-ranked lncRNA genes for ethanol drinking phenotypes.Adv Drug Alcohol Res2022
36055466Effect of chronic intermittent ethanol vapor exposure on RNA content of brain-derived extracellular vesicles.Alcohol2022
32357359Reduced sedation and increased ethanol consumption in knock-in mice expressing an ethanol insensitive alpha 2 subunit of the glycine receptor.Neuropsychopharmacology2021
33526823MAP2 is differentially phosphorylated in schizophrenia, altering its function.Mol Psychiatry2021
34406874Hippocampal β2-GABA<sub>A</sub> receptors mediate LTP suppression by etomidate and contribute to long-lasting feedback but not feedforward inhibition of pyramidal neurons.J Neurophysiol2021
34848542A Kalirin missense mutation enhances dendritic RhoA signaling and leads to regression of cortical dendritic arbors across development.Proc Natl Acad Sci U S A2021
34677900A quantitative trait variant in Gabra2 underlies increased methamphetamine stimulant sensitivity.Genes Brain Behav2021
34086081Gabra2 is a genetic modifier of Dravet syndrome in mice.Mamm Genome2021
33461664Exposure to drugs of abuse induce effects that persist across generations.Int Rev Neurobiol2021
33052417The escalation in ethanol consumption following chronic intermittent ethanol exposure is blunted in mice expressing ethanol-resistant GluN1 or GluN2A NMDA receptor subunits.Psychopharmacology (Berl)2021
32893479A long non-coding RNA (Lrap) modulates brain gene expression and levels of alcohol consumption in rats.Genes Brain Behav2021
30884072Influence of nonsynaptic α1 glycine receptors on ethanol consumption and place preference.Addict Biol2020
33604589CRISPR Turbo Accelerated KnockOut (CRISPy TAKO) for Rapid <i>in vivo</i> Screening of Gene Function.Front Genome Ed2020
31872888Knock-in Mice Expressing an Ethanol-Resistant GluN2A NMDA Receptor Subunit Show Altered Responses to Ethanol.Alcohol Clin Exp Res2020
32971974Effects of Paternal Preconception Vapor Alcohol Exposure Paradigms on Behavioral Responses in Offspring.Brain Sci2020
32445808Coincubation of sperm with epididymal extracellular vesicle preparations from chronic intermittent ethanol-treated mice is sufficient to impart anxiety-like and ethanol-induced behaviors to adult progeny.Alcohol2020
31233806Age-dependent impairment of metabotropic glutamate receptor 2-dependent long-term depression in the mouse striatum by chronic ethanol exposure.Alcohol2020
30621855Gene-edited CRISPy Critters for alcohol research.Alcohol2019
30984232Identification of a Functional Non-coding Variant in the GABA <sub><i>A</i></sub> Receptor α2 Subunit of the C57BL/6J Mouse Reference Genome: Major Implications for Neuroscience Research.Front Genet2019
30936145Hepatocyte-Specific Ablation or Whole-Body Inhibition of Xanthine Oxidoreductase in Mice Corrects Obesity-Induced Systemic Hyperuricemia Without Improving Metabolic Abnormalities.Diabetes2019
30908630Intergenerational Effects of Alcohol: A Review of Paternal Preconception Ethanol Exposure Studies and Epigenetic Mechanisms in the Male Germline.Alcohol Clin Exp Res2019
30845665Paternal Preconception Every-Other-Day Ethanol Drinking Alters Behavior and Ethanol Consumption in Offspring.Brain Sci2019
30817077Scn4b regulates the hypnotic effects of ethanol and other sedative drugs.Genes Brain Behav2019
29323417Loss of Ethanol Inhibition of N-Methyl-D-Aspartate Receptor-Mediated Currents and Plasticity of Cerebellar Synapses in Mice Expressing the GluN1(F639A) Subunit.Alcohol Clin Exp Res2018
30450042Paternal Preconception Chronic Variable Stress Confers Attenuated Ethanol Drinking Behavior Selectively to Male Offspring in a Pre-Stress Environment Dependent Manner.Front Behav Neurosci2018
29472946Heavy Chronic Intermittent Ethanol Exposure Alters Small Noncoding RNAs in Mouse Sperm and Epididymosomes.Front Genet2018
29407767Involvement of glycine receptor α1 subunits in cannabinoid-induced analgesia.Neuropharmacology2018
29309503Role of TLR4 in the Modulation of Central Amygdala GABA Transmission by CRF Following Restraint Stress.Alcohol Alcohol2018
27876231Paternal preconception alcohol exposure imparts intergenerational alcohol-related behaviors to male offspring on a pure C57BL/6J background.Alcohol2017
28270746Effects of Repeated Ethanol Exposures on NMDA Receptor Expression and Locomotor Sensitization in Mice Expressing Ethanol Resistant NMDA Receptors.Front Neurosci2017
28243192The Sodium Channel β4 Auxiliary Subunit Selectively Controls Long-Term Depression in Core Nucleus Accumbens Medium Spiny Neurons.Front Cell Neurosci2017
28473323GABA<sub>A</sub> receptor α<sub>4</sub>-subunit knockout enhances lung inflammation and airway reactivity in a murine asthma model.Am J Physiol Lung Cell Mol Physiol2017
28395929Epigenetic mediators and consequences of excessive alcohol consumption.Alcohol2017
29163049Tagging of Endogenous BK Channels with a Fluorogen-Activating Peptide Reveals β4-Mediated Control of Channel Clustering in Cerebellum.Front Cell Neurosci2017
28623169Mutation of the inhibitory ethanol site in GABA<sub>A</sub> ρ1 receptors promotes tolerance to ethanol-induced motor incoordination.Neuropharmacology2017
28799801Cross-generational effects of alcohol dependence in humans on HRAS and TP53 methylation in offspring.Epigenomics2017
27986929Genetic and Pharmacologic Manipulation of TLR4 Has Minimal Impact on Ethanol Consumption in Rodents.J Neurosci2017
26868730Chromatin immunoprecipitation and gene expression analysis of neuronal subtypes after fluorescence activated cell sorting.J Neurosci Methods2016
26575788Generation of a KOR-Cre knockin mouse strain to study cells involved in kappa opioid signaling.Genesis2016
27286933Paternal preconception ethanol exposure blunts hypothalamic-pituitary-adrenal axis responsivity and stress-induced excessive fluid intake in male mice.Alcohol2016
27274063APE1/Ref-1 facilitates recovery of gray and white matter and neurological function after mild stroke injury.Proc Natl Acad Sci U S A2016
25950631Brains, genes, and primates.Neuron2015
26300722Repeated vapor ethanol exposure induces transient histone modifications in the brain that are modified by genotype and brain region.Front Mol Neurosci2015
25914623Reduction in focal ictal activity following transplantation of MGE interneurons requires expression of the GABAA receptor α4 subunit.Front Cell Neurosci2015
25887183Drinking beyond a lifetime: New and emerging insights into paternal alcohol exposure on subsequent generations.Alcohol2015
25827497Manipulations of extracellular Loop 2 in α1 GlyR ultra-sensitive ethanol receptors (USERs) enhance receptor sensitivity to isoflurane, ethanol, and lidocaine, but not propofol.Neuroscience2015
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Collaborators

Douglas B Matthews
University of Wisconsin
Co-authored papers 4
Megan K Mulligan
University of Tennessee Health Science Center.
Co-authored papers 3
Robert W Williams
Mayo Clinic
Co-authored papers 3
Robert A Sweet
University of Pittsburgh
Co-authored papers 2
Simon C Watkins
Center for Molecular Imaging, University of Pittsburgh School of Medicine
Co-authored papers 2
Sean P Farris
Center for Neuroscience, University of Pittsburgh
Co-authored papers 2
Marcelo F Lopez
Charleston Alcohol Research Center, Medical University of South Carolina
Co-authored papers 2
Amanda J Roberts
The Scripps Research Institute
Co-authored papers 2
Patrick M Kochanek
University of Pittsburgh School of Medicine
Co-authored papers 2
Donald H Chace
Medolac Laboratories A Public Benefit Corporation
Co-authored papers 1
Jennifer A Kearney
Feinberg School of Medicine, Northwestern University
Co-authored papers 1
Megan E Garver
University of Pittsburgh
Co-authored papers 1
Nathan A Yates
University of Pittsburgh School of Medicine
Co-authored papers 1
Feng Zhang
Massachusetts Institute of Technology, USA Broad Institute
Co-authored papers 1
Daniel Pomp
Co-authored papers 1
Murray H Brilliant
Marshfield Clinic Research Institute
Co-authored papers 1
Sotirios Keros
Weill Cornell Medical College
Co-authored papers 1
Guoping Feng
Co-authored papers 1
Timothy R Billiar
University of Pittsburgh
Co-authored papers 1
Robert Hitzemann
Portland Alcohol Research Center, Oregon Health and Science University
Co-authored papers 1
M L MacDonald
University of Pittsburgh
Co-authored papers 1
Boris Tabakoff
University of Colorado Health Science Center
Co-authored papers 1
Benedict Paten
UC Santa Cruz Genomics Institute, University of California
Co-authored papers 1
Pei Tang
Sichuan University
Co-authored papers 1
Paul D Robbins
University of Minnesota
Co-authored papers 1
Paula L Hoffman
University of Colorado
Co-authored papers 1
Andrew R Tapper
Co-authored papers 1
Stewart A Anderson
Co-authored papers 1
Joseph T Coyle
Harvard Medical School and McLean Hospital
Co-authored papers 1
Yan Xu
Nanjing Drum Tower Hospital
Co-authored papers 1
Release 1.2