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Author Details

Anne S De Groot
University of Georgia
1989
223
40
PMIDPaper TitleJournal TitlePublished Year
37666923Optimization of therapeutic antibodies for reduced self-association and non-specific binding via interpretable machine learning.Nat Biomed Eng2024
36285342H1N1 G4 swine influenza T cell epitope analysis in swine and human vaccines and circulating strains uncovers potential risk to swine and humans.Influenza Other Respir Viruses2023
38022550Does human homology reduce the potential immunogenicity of non-antibody scaffolds?Front Immunol2023
37705976Identification of immunodominant T cell epitopes induced by natural Zika virus infection.Front Immunol2023
37697150Immunoinformatic Risk Assessment of Host Cell Proteins During Process Development for Biologic Therapeutics.AAPS J2023
37931868Development of IFNβ-1a versions with reduced immunogenicity and full in vitro biological activity for the treatment of multiple sclerosis.Clin Immunol2023
37020947Specific sequence mutations in a long-lasting rhIFN-α2b version reduce <i>in vitro</i> and <i>in vivo</i> immunogenicity and increase <i>in vitro</i> protein stability.Heliyon2023
37467878Immunogenicity risk assessment of synthetic peptide drugs and their impurities.Drug Discov Today2023
36626370Diversity and evolution of computationally predicted T cell epitopes against human respiratory syncytial virus.PLoS Comput Biol2023
34882038Neoantigen-based personalized cancer vaccines: the emergence of precision cancer immunotherapy.Expert Rev Vaccines2022
35651616Evaluation of a Human T Cell-Targeted Multi-Epitope Vaccine for Q Fever in Animal Models of <i>Coxiella burnetii</i> Immunity.Front Immunol2022
35704783Novel H7N9 influenza immunogen design enhances mobilization of seasonal influenza T cell memory in H3N2 pre-immune mice.Hum Vaccin Immunother2022
36945694<i>In silico</i> Immunogenicity Assessment for Sequences Containing Unnatural Amino Acids: A Method Using Existing <i>in silico</i> Algorithm Infrastructure and a Vision for Future Enhancements.Front Drug Discov (Lausanne)2022
36589936A story-telling cloth approach to motivating cervical cancer screening in Mali.Front Public Health2022
36373716Expanding access to COVID-19 testing, vaccination and treatment at a free clinic for uninsured Spanish-speaking adults in Providence, RI.Hum Vaccin Immunother2022
33412295Identification of a potent regulatory T cell epitope in factor V that modulates CD4+ and CD8+ memory T cell responses.Clin Immunol2021
33793595Clinical outcomes of a community clinic-based lifestyle change program for prevention and management of metabolic syndrome: Results of the 'Vida Sana/Healthy Life' program.PLoS One2021
34798238Development of highly stable and de-immunized versions of recombinant alpha interferon: Promising candidates for the treatment of chronic and emerging viral diseases.Clin Immunol2021
34220802Immune Tolerance-Adjusted Personalized Immunogenicity Prediction for Pompe Disease.Front Immunol2021
34066605Quantifying the Persistence of Vaccine-Related T Cell Epitopes in Circulating Swine Influenza A Strains from 2013-2017.Vaccines (Basel)2021
33986292Highly conserved, non-human-like, and cross-reactive SARS-CoV-2 T cell epitopes for COVID-19 vaccine design and validation.NPJ Vaccines2021
34150707Recruitment, Training, and Roles of the Bilingual, Bicultural <i>Navegantes</i>: Developing a Specialized Workforce of Community Health Workers to Serve a Low-Income, Spanish-Speaking Population in Rhode Island.Front Public Health2021
34060724Development of a novel fully functional coagulation factor VIII with reduced immunogenicity utilizing an in silico prediction and deimmunization approach.J Thromb Haemost2021
33953711Tregitopes Improve Asthma by Promoting Highly Suppressive and Antigen-Specific Tregs.Front Immunol2021
34168657Bridging Computational Vaccinology and Vaccine Development Through Systematic Identification, Characterization, and Downselection of Conserved and Variable Circumsporozoite Protein CD4 T Cell Epitopes From Diverse <i>Plasmodium falciparum</i> Strains.Front Immunol2021
33976291Multi-step screening of neoantigens' HLA- and TCR-interfaces improves prediction of survival.Sci Rep2021
34025684Identification, Selection and Immune Assessment of Liver Stage CD8 T Cell Epitopes From <i>Plasmodium falciparum</i>.Front Immunol2021
34305923Identification and Immune Assessment of T Cell Epitopes in Five <i>Plasmodium falciparum</i> Blood Stage Antigens to Facilitate Vaccine Candidate Selection and Optimization.Front Immunol2021
33278563Self-Replicating RNAs Drive Protective Anti-tumor T Cell Responses to Neoantigen Vaccine Targets in a Combinatorial Approach.Mol Ther2021
30614773Immune escape and immune camouflage may reduce the efficacy of RTS,S vaccine in Malawi.Hum Vaccin Immunother2020
33496509Quantifying quality of care at a PA student-led free diabetes clinic.JAAPA2020
31951773<i>In silico</i> identification and modification of T cell epitopes in pertussis antigens associated with tolerance.Hum Vaccin Immunother2020
33126788Responding to COVID-19 in an Uninsured Hispanic/Latino Community: Testing, Education and Telehealth at a Free Clinic in Providence.R I Med J (2013)2020
33123135New Immunoinformatics Tools for Swine: Designing Epitope-Driven Vaccines, Predicting Vaccine Efficacy, and Making Vaccines on Demand.Front Immunol2020
32803994European Immunogenicity Platform 11th Open Scientific Symposium on immunogenicity of biopharmaceuticals.Bioanalysis2020
32770104Novel multiparameter correlates of Coxiella burnetii infection and vaccination identified by longitudinal deep immune profiling.Sci Rep2020
32908981The immune vulnerability landscape of the 2019 Novel Coronavirus, SARS-CoV-2.bioRxiv2020
32962468Exploit T cell Immunity for Rapid, Safe and Effective COVID-19 Vaccines.Expert Rev Vaccines2020
32783766Immune-engineered H7N9 influenza hemagglutinin improves protection against viral influenza virus challenge.Hum Vaccin Immunother2020
32695107T-Cell Dependent Immunogenicity of Protein Therapeutics Pre-clinical Assessment and Mitigation-Updated Consensus and Review 2020.Front Immunol2020
32278900T cell epitope content comparison (EpiCC) analysis demonstrates a bivalent PCV2 vaccine has greater T cell epitope overlap with field strains than monovalent PCV2 vaccines.Vet Immunol Immunopathol2020
32318055Better Epitope Discovery, Precision Immune Engineering, and Accelerated Vaccine Design Using Immunoinformatics Tools.Front Immunol2020
31629569Differential functional patterns of memory CD4<sup>+</sup> and CD8<sup>+</sup> T-cells from volunteers immunized with Ty21a typhoid vaccine observed using a recombinant Escherichia coli system expressing S. Typhi proteins.Vaccine2020
30826446Design of a multiepitopic Zaire ebolavirus protein and its expression in plant cells.J Biotechnol2019
31695065Therapeutic administration of Tregitope-Human Albumin Fusion with Insulin Peptides to promote Antigen-Specific Adaptive Tolerance Induction.Sci Rep2019
31428586Multi-antigen Vaccination With Simultaneous Engagement of the OX40 Receptor Delays Malignant Mesothelioma Growth and Increases Survival in Animal Models.Front Oncol2019
31594990Publisher Correction: A humanized mouse model identifies key amino acids for low immunogenicity of H7N9 vaccines.Sci Rep2019
31248687A prime-boost concept using a T-cell epitope-driven DNA vaccine followed by a whole virus vaccine effectively protected pigs in the pandemic H1N1 pig challenge model.Vaccine2019
31331958Coxiella burnetii Epitope-Specific T-Cell Responses in Patients with Chronic Q Fever.Infect Immun2019
31331771Highly conserved influenza T cell epitopes induce broadly protective immunity.Vaccine2019
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Collaborators

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University of Colorado - Anschutz Medical Campus
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University of British Columbia
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Co-authored papers 8
University of Science
Co-authored papers 7
University of Massachusetts Medical School
Co-authored papers 6
Center for Cancer Research, National Cancer Institute, National Institutes of Health
Co-authored papers 6
Brown University, Kilguss Institut
Co-authored papers 6
Co-authored papers 5
Brown University, Rhode Island Providence VA Medical Center
Co-authored papers 5
Wistar Institute
Co-authored papers 5
University of Copenhagen
Co-authored papers 5
Brock University
Co-authored papers 4
University of Michigan Medical School ann arbor
Co-authored papers 4
Drexel University College of Medicine
Co-authored papers 3
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Institute for Social Science Research, The University of Queensland
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Warren Alpert School of Medicine at Brown University
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Dana-Farber Cancer Institute, Harvard Medical School
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Daejeon St. Mary's Hospital, College of Medicine, The Catholic University of Korea
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Saint Louis University School of Medicine
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University of Pennsylvania
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Faculty of Medicine and Odonto-Stomatology (FMOS)/University of Sciences
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Boston Children's Hospital
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