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Author Details

Arthur Weiss
University of California san francisco
1972
353
115
Andrej Sali (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
37788477Peeking Into the Black Box of T Cell Receptor Signaling.Annu Rev Immunol2024
37788477Peeking Into the Black Box of T Cell Receptor Signaling.Annu Rev Immunol2024
36564464Unique roles of co-receptor-bound LCK in helper and cytotoxic T cells.Nat Immunol2023
38091950TCR signaling promotes formation of an STS1-Cbl-b complex with pH-sensitive phosphatase activity that suppresses T cell function in acidic environments.Immunity2023
36907684Cold Spring Harbor Laboratory 2022: emerging insights and viewpoints in immunology.Trends Immunol2023
36581712The phosphatidylinositol-transfer protein Nir3 promotes PI(4,5)P<sub>2</sub> replenishment in response to TCR signaling during T cell development and survival.Nat Immunol2023
36564464Unique roles of co-receptor-bound LCK in helper and cytotoxic T cells.Nat Immunol2023
36747815Accumulation of TCR signaling from self-antigens in naive CD8 T cells mitigates early responsiveness.bioRxiv2023
36914891A single-amino acid substitution in the adaptor LAT accelerates TCR proofreading kinetics and alters T-cell selection, maintenance and function.Nat Immunol2023
38091950TCR signaling promotes formation of an STS1-Cbl-b complex with pH-sensitive phosphatase activity that suppresses T cell function in acidic environments.Immunity2023
36747815Accumulation of TCR signaling from self-antigens in naive CD8 T cells mitigates early responsiveness.bioRxiv2023
36581712The phosphatidylinositol-transfer protein Nir3 promotes PI(4,5)P<sub>2</sub> replenishment in response to TCR signaling during T cell development and survival.Nat Immunol2023
36914891A single-amino acid substitution in the adaptor LAT accelerates TCR proofreading kinetics and alters T-cell selection, maintenance and function.Nat Immunol2023
36907684Cold Spring Harbor Laboratory 2022: emerging insights and viewpoints in immunology.Trends Immunol2023
34923645ZAP70, too little, too much can lead to autoimmunity.Immunol Rev2022
34923645ZAP70, too little, too much can lead to autoimmunity.Immunol Rev2022
33974042Cbl-b deficiency prevents functional but not phenotypic T cell anergy.J Exp Med2021
33531381A disease-associated mutation that weakens ZAP70 autoinhibition enhances responses to weak and self-ligands.Sci Signal2021
33936119Adapting T Cell Receptor Ligand Discrimination Capability <i>via</i> LAT.Front Immunol2021
33931484Itk Promotes the Integration of TCR and CD28 Costimulation through Its Direct Substrates SLP-76 and Gads.J Immunol2021
33974042Cbl-b deficiency prevents functional but not phenotypic T cell anergy.J Exp Med2021
34675079Acute Csk inhibition hinders B cell activation by constraining the PI3 kinase pathway.Proc Natl Acad Sci U S A2021
34821217Reversible phosphorylation of cyclin T1 promotes assembly and stability of P-TEFb.Elife2021
33531381A disease-associated mutation that weakens ZAP70 autoinhibition enhances responses to weak and self-ligands.Sci Signal2021
33931484Itk Promotes the Integration of TCR and CD28 Costimulation through Its Direct Substrates SLP-76 and Gads.J Immunol2021
34675079Acute Csk inhibition hinders B cell activation by constraining the PI3 kinase pathway.Proc Natl Acad Sci U S A2021
34821217Reversible phosphorylation of cyclin T1 promotes assembly and stability of P-TEFb.Elife2021
33936119Adapting T Cell Receptor Ligand Discrimination Capability <i>via</i> LAT.Front Immunol2021
33020303How the T cell signaling network processes information to discriminate between self and agonist ligands.Proc Natl Acad Sci U S A2020
33020303How the T cell signaling network processes information to discriminate between self and agonist ligands.Proc Natl Acad Sci U S A2020
30429161The <i>Gp1ba-Cre</i> transgenic mouse: a new model to delineate platelet and leukocyte functions.Blood2019
31641081CD45 functions as a signaling gatekeeper in T cells.Sci Signal2019
31611699Slow phosphorylation of a tyrosine residue in LAT optimizes T cell ligand discrimination.Nat Immunol2019
30429161The <i>Gp1ba-Cre</i> transgenic mouse: a new model to delineate platelet and leukocyte functions.Blood2019
31285342Adaptation by naïve CD4<sup>+</sup> T cells to self-antigen-dependent TCR signaling induces functional heterogeneity and tolerance.Proc Natl Acad Sci U S A2019
30814157CRACR2a is a calcium-activated dynein adaptor protein that regulates endocytic traffic.J Cell Biol2019
31076553Switch-like activation of Bruton's tyrosine kinase by membrane-mediated dimerization.Proc Natl Acad Sci U S A2019
31641081CD45 functions as a signaling gatekeeper in T cells.Sci Signal2019
31611699Slow phosphorylation of a tyrosine residue in LAT optimizes T cell ligand discrimination.Nat Immunol2019
31285342Adaptation by naïve CD4<sup>+</sup> T cells to self-antigen-dependent TCR signaling induces functional heterogeneity and tolerance.Proc Natl Acad Sci U S A2019
30814157CRACR2a is a calcium-activated dynein adaptor protein that regulates endocytic traffic.J Cell Biol2019
31076553Switch-like activation of Bruton's tyrosine kinase by membrane-mediated dimerization.Proc Natl Acad Sci U S A2019
29237129ZAP-70 in Signaling, Biology, and Disease.Annu Rev Immunol2018
29915297Lck promotes Zap70-dependent LAT phosphorylation by bridging Zap70 to LAT.Nat Immunol2018
29269020TCR Signaling: Mechanisms of Initiation and Propagation.Trends Biochem Sci2018
29301754Maintenance of murine platelet homeostasis by the kinase Csk and phosphatase CD148.Blood2018
29547119Fine-tuning of substrate preferences of the Src-family kinase Lck revealed through a high-throughput specificity screen.Elife2018
29237129ZAP-70 in Signaling, Biology, and Disease.Annu Rev Immunol2018
29632189Genome-wide CRISPR screen identifies FAM49B as a key regulator of actin dynamics and T cell activation.Proc Natl Acad Sci U S A2018
29915297Lck promotes Zap70-dependent LAT phosphorylation by bridging Zap70 to LAT.Nat Immunol2018
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Collaborators

University of California berkeley
Co-authored papers 15
Stanford University School of Medicine
Co-authored papers 7
University of California San Francisco
Co-authored papers 7
Co-authored papers 6
University of California San Diego
Co-authored papers 4
University of California San Diego
Co-authored papers 4
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University of California San Francisco
Co-authored papers 3
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Co-authored papers 3
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Salk Institute for Biological Studies
Co-authored papers 3
Princess Margaret Cancer Centre, University Health Network
Co-authored papers 3
National Institute of Allergy and Infectious Diseases, National Institutes of Health
Co-authored papers 3
University of British Columbia
Co-authored papers 2
Co-authored papers 2
Co-authored papers 2
University of California san francisco
Co-authored papers 2
The Children's Hospital of Philadelphia
Co-authored papers 2
university of california los angeles
Co-authored papers 2
Children's Hospital of Philadelphia
Co-authored papers 2
Co-authored papers 2
University of British Columbia
Co-authored papers 2
Calico Life Sciences LLC
Co-authored papers 2
University of California san francisco
Co-authored papers 2
University of California berkeley
Co-authored papers 2
Co-authored papers 2
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University of Washington
Co-authored papers 2