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Author Details

Michael C Oldham
University of California san francisco
2004
49
35
Kirsten Obernier (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
37645893Deconstructing intratumoral heterogeneity through multiomic and multiscale analysis of serial sections.bioRxiv2024
36915679Bulk and mosaic deletions of <i>Egfr</i> reveal regionally defined gliogenesis in the developing mouse forebrain.iScience2023
35084970Nests of dividing neuroblasts sustain interneuron production for the developing human brain.Science2022
35748297Generation of functional human oligodendrocytes from dermal fibroblasts by direct lineage conversion.Development2022
33512429Diagnostic blood RNA profiles for human acute spinal cord injury.J Exp Med2021
33792567ALS-associated mutation FUS-R521C causes DNA damage and RNA splicing defects.J Clin Invest2021
33762407Positive Controls in Adults and Children Support That Very Few, If Any, New Neurons Are Born in the Adult Human Hippocampus.J Neurosci2021
31580842MicroRNA Ratios Distinguish Melanomas from Nevi.J Invest Dermatol2020
31611708Profiling the mouse brain endothelial transcriptome in health and disease models reveals a core blood-brain barrier dysfunction module.Nat Neurosci2019
29681511A Glial Signature and Wnt7 Signaling Regulate Glioma-Vascular Interactions and Tumor Microenvironment.Cancer Cell2018
30154505Variation among intact tissue samples reveals the core transcriptional features of human CNS cell classes.Nat Neurosci2018
30096308Sequencing Diversity One Cell at a Time.Cell2018
30526879Does Adult Neurogenesis Persist in the Human Hippocampus?Cell Stem Cell2018
28449024Secretagogin is Expressed by Developing Neocortical GABAergic Neurons in Humans but not Mice and Increases Neurite Arbor Size and Complexity.Cereb Cortex2018
29513649Human hippocampal neurogenesis drops sharply in children to undetectable levels in adults.Nature2018
28591140Correction: Pleiotropic Mechanisms Indicated for Sex Differences in Autism.PLoS Genet2017
28457749An FAK-YAP-mTOR Signaling Axis Regulates Stem Cell-Based Tissue Renewal in Mice.Cell Stem Cell2017
28475038Resolving stem and progenitor cells in the adult mouse incisor through gene co-expression analysis.Elife2017
27114033Progranulin Deficiency Promotes Circuit-Specific Synaptic Pruning by Microglia via Complement Activation.Cell2016
27846226Pleiotropic Mechanisms Indicated for Sex Differences in Autism.PLoS Genet2016
26212322miR-302 Is Required for Timing of Neural Differentiation, Neural Tube Closure, and Embryonic Viability.Cell Rep2015
26406371Molecular identity of human outer radial glia during cortical development.Cell2015
26605877Transcriptional architecture of the human brain.Nat Neurosci2015
24630794Two miRNA clusters reveal alternative paths in late-stage reprogramming.Cell Stem Cell2014
25391964Radial glia require PDGFD-PDGFRβ signalling in human but not mouse neocortex.Nature2014
24867641Distinct and separable roles for EZH2 in neurogenic astroglia.Elife2014
24887289Analysis of Mll1 deficiency identifies neurogenic transcriptional modules and Brn4 as a factor for direct astrocyte-to-neuron reprogramming.Neurosurgery2014
24509083ALS-associated mutation FUS-R521C causes DNA damage and RNA splicing defects.J Clin Invest2014
23583100Integration of genome-wide approaches identifies lncRNAs of adult neural stem cells and their progeny in vivo.Cell Stem Cell2013
23840004Expression profiling of Aldh1l1-precursors in the developing spinal cord reveals glial lineage-specific genes and direct Sox9-Nfe2l1 interactions.Glia2013
23431031Human-specific regulation of MeCP2 levels in fetal brains by microRNA miR-483-5p.Genes Dev2013
22920253Human-specific transcriptional networks in the brain.Neuron2012
22691535Network methods for describing sample relationships in genomic datasets: application to Huntington's disease.BMC Syst Biol2012
21467265Neurons show distinctive DNA methylation profile and higher interindividual variations compared with non-neurons.Genome Res2011
21943601Functional genomic analyses identify pathways dysregulated by progranulin deficiency, implicating Wnt signaling.Neuron2011
21283776Is my network module preserved and reproducible?PLoS Comput Biol2011
20553896Detecting network modules in fMRI time series: a weighted network analysis approach.Neuroimage2010
20961428Is human blood a good surrogate for brain tissue in transcriptional studies?BMC Genomics2010
19638972The organization of the transcriptional network in specific neuronal classes.Mol Syst Biol2009
18256261A systems level analysis of transcriptional changes in Alzheimer's disease and normal aging.J Neurosci2008
18849986Functional organization of the transcriptome in human brain.Nat Neurosci2008
17978184Genome-wide analyses of human perisylvian cerebral cortical patterning.Proc Natl Acad Sci U S A2007
17999357Identification of the transcriptional targets of FOXP2, a gene linked to speech and language, in developing human brain.Am J Hum Genet2007
16552432Comparative genomics: grasping human transcriptome evolution: what does it all mean?Heredity (Edinb)2006
17101986Conservation and evolution of gene coexpression networks in human and chimpanzee brains.Proc Natl Acad Sci U S A2006
16417618Deconstructing language by comparative gene expression: from neurobiology to microarray.Genes Brain Behav2006
16414979Inhaled marijuana smoke disrupts mitochondrial energetics in pulmonary epithelial cells in vivo.Am J Physiol Lung Cell Mol Physiol2006
15756295Evolutionary genetics: the human brain -- adaptation at many levels.Eur J Hum Genet2005
15520794Human brain evolution: insights from microarrays.Nat Rev Genet2004
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Collaborators

University of California los angeles
Co-authored papers 14
University of California san francisco
Co-authored papers 8
David Geffen School of Medicine, University of California los angeles
Co-authored papers 7
University of California san francisco
Co-authored papers 7
University of California san francisco
Co-authored papers 6
University of California san francisco
Co-authored papers 6
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Co-authored papers 5
David Geffen School of Medicine, University of California los angeles
Co-authored papers 4
University of California san francisco
Co-authored papers 4
Cavanilles Institute, University of Valencia
Co-authored papers 4
University of California san francisco
Co-authored papers 3
University of California at San Francisco
Co-authored papers 3
University of California San Francisco
Co-authored papers 3
UCSF Medical School
Co-authored papers 3
Wellcome Trust-Medical Research Council Stem Cell Institute and.
Co-authored papers 3
Co-authored papers 2
Co-authored papers 2
Genentech Inc.
Co-authored papers 2
Co-authored papers 2
The Picower Institute for Learning and Memory, Massachusetts Institute of Technology
Co-authored papers 2
Neurona Therapeutics Inc.
Co-authored papers 2
Co-authored papers 2
University of California san francisco
Co-authored papers 2
Harvard T.H. Chan School of Public Health
Co-authored papers 2
University of California san francisco
Co-authored papers 2
University of California san francisco
Co-authored papers 2
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The MIND Institute, University of California davis
Co-authored papers 2