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Author Details
Full Name
Michael C Oldham
Affiliation
University of California san francisco
ORCID
Career Start Year
2004
Papers
49
H Index
35
Expertise
CM4AI Collaborator
Kirsten Obernier (CM4AI)
PMID
Paper Title
Journal Title
Published Year
37645893
Deconstructing intratumoral heterogeneity through multiomic and multiscale analysis of serial sections.
bioRxiv
2024
36915679
Bulk and mosaic deletions of <i>Egfr</i> reveal regionally defined gliogenesis in the developing mouse forebrain.
iScience
2023
35084970
Nests of dividing neuroblasts sustain interneuron production for the developing human brain.
Science
2022
35748297
Generation of functional human oligodendrocytes from dermal fibroblasts by direct lineage conversion.
Development
2022
33512429
Diagnostic blood RNA profiles for human acute spinal cord injury.
J Exp Med
2021
33792567
ALS-associated mutation FUS-R521C causes DNA damage and RNA splicing defects.
J Clin Invest
2021
33762407
Positive Controls in Adults and Children Support That Very Few, If Any, New Neurons Are Born in the Adult Human Hippocampus.
J Neurosci
2021
31580842
MicroRNA Ratios Distinguish Melanomas from Nevi.
J Invest Dermatol
2020
31611708
Profiling the mouse brain endothelial transcriptome in health and disease models reveals a core blood-brain barrier dysfunction module.
Nat Neurosci
2019
29681511
A Glial Signature and Wnt7 Signaling Regulate Glioma-Vascular Interactions and Tumor Microenvironment.
Cancer Cell
2018
30154505
Variation among intact tissue samples reveals the core transcriptional features of human CNS cell classes.
Nat Neurosci
2018
30096308
Sequencing Diversity One Cell at a Time.
Cell
2018
30526879
Does Adult Neurogenesis Persist in the Human Hippocampus?
Cell Stem Cell
2018
28449024
Secretagogin is Expressed by Developing Neocortical GABAergic Neurons in Humans but not Mice and Increases Neurite Arbor Size and Complexity.
Cereb Cortex
2018
29513649
Human hippocampal neurogenesis drops sharply in children to undetectable levels in adults.
Nature
2018
28591140
Correction: Pleiotropic Mechanisms Indicated for Sex Differences in Autism.
PLoS Genet
2017
28457749
An FAK-YAP-mTOR Signaling Axis Regulates Stem Cell-Based Tissue Renewal in Mice.
Cell Stem Cell
2017
28475038
Resolving stem and progenitor cells in the adult mouse incisor through gene co-expression analysis.
Elife
2017
27114033
Progranulin Deficiency Promotes Circuit-Specific Synaptic Pruning by Microglia via Complement Activation.
Cell
2016
27846226
Pleiotropic Mechanisms Indicated for Sex Differences in Autism.
PLoS Genet
2016
26212322
miR-302 Is Required for Timing of Neural Differentiation, Neural Tube Closure, and Embryonic Viability.
Cell Rep
2015
26406371
Molecular identity of human outer radial glia during cortical development.
Cell
2015
26605877
Transcriptional architecture of the human brain.
Nat Neurosci
2015
24630794
Two miRNA clusters reveal alternative paths in late-stage reprogramming.
Cell Stem Cell
2014
25391964
Radial glia require PDGFD-PDGFRβ signalling in human but not mouse neocortex.
Nature
2014
24867641
Distinct and separable roles for EZH2 in neurogenic astroglia.
Elife
2014
24887289
Analysis of Mll1 deficiency identifies neurogenic transcriptional modules and Brn4 as a factor for direct astrocyte-to-neuron reprogramming.
Neurosurgery
2014
24509083
ALS-associated mutation FUS-R521C causes DNA damage and RNA splicing defects.
J Clin Invest
2014
23583100
Integration of genome-wide approaches identifies lncRNAs of adult neural stem cells and their progeny in vivo.
Cell Stem Cell
2013
23840004
Expression profiling of Aldh1l1-precursors in the developing spinal cord reveals glial lineage-specific genes and direct Sox9-Nfe2l1 interactions.
Glia
2013
23431031
Human-specific regulation of MeCP2 levels in fetal brains by microRNA miR-483-5p.
Genes Dev
2013
22920253
Human-specific transcriptional networks in the brain.
Neuron
2012
22691535
Network methods for describing sample relationships in genomic datasets: application to Huntington's disease.
BMC Syst Biol
2012
21467265
Neurons show distinctive DNA methylation profile and higher interindividual variations compared with non-neurons.
Genome Res
2011
21943601
Functional genomic analyses identify pathways dysregulated by progranulin deficiency, implicating Wnt signaling.
Neuron
2011
21283776
Is my network module preserved and reproducible?
PLoS Comput Biol
2011
20553896
Detecting network modules in fMRI time series: a weighted network analysis approach.
Neuroimage
2010
20961428
Is human blood a good surrogate for brain tissue in transcriptional studies?
BMC Genomics
2010
19638972
The organization of the transcriptional network in specific neuronal classes.
Mol Syst Biol
2009
18256261
A systems level analysis of transcriptional changes in Alzheimer's disease and normal aging.
J Neurosci
2008
18849986
Functional organization of the transcriptome in human brain.
Nat Neurosci
2008
17978184
Genome-wide analyses of human perisylvian cerebral cortical patterning.
Proc Natl Acad Sci U S A
2007
17999357
Identification of the transcriptional targets of FOXP2, a gene linked to speech and language, in developing human brain.
Am J Hum Genet
2007
16552432
Comparative genomics: grasping human transcriptome evolution: what does it all mean?
Heredity (Edinb)
2006
17101986
Conservation and evolution of gene coexpression networks in human and chimpanzee brains.
Proc Natl Acad Sci U S A
2006
16417618
Deconstructing language by comparative gene expression: from neurobiology to microarray.
Genes Brain Behav
2006
16414979
Inhaled marijuana smoke disrupts mitochondrial energetics in pulmonary epithelial cells in vivo.
Am J Physiol Lung Cell Mol Physiol
2006
15756295
Evolutionary genetics: the human brain -- adaptation at many levels.
Eur J Hum Genet
2005
15520794
Human brain evolution: insights from microarrays.
Nat Rev Genet
2004
1 - 49 of 49
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