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Author Details

Magnus H????k
Texas A&M Health Science Center Institute of Biosciences and Technology
1974
304
98
PMIDPaper TitleJournal TitlePublished Year
37828992Antibodies to coagulase of <i>Staphylococcus aureus</i> crossreact to Efb and reveal different binding of shared fibrinogen binding repeats.Front Immunol2023
37548398Click display: a rapid and efficient in vitro protein display method for directed evolution.Nucleic Acids Res2023
35309920The Collagen Receptor Discoidin Domain Receptor 1b Enhances Integrin β1-Mediated Cell Migration by Interacting With Talin and Promoting Rac1 Activation.Front Cell Dev Biol2022
35372322Prokaryotic Collagen-Like Proteins as Novel Biomaterials.Front Bioeng Biotechnol2022
37101428KRAS Inhibitor that Simultaneously Inhibits Nucleotide Exchange Activity and Effector Engagement.ACS Bio Med Chem Au2022
35041705Fibrin(ogen) engagement of S. aureus promotes the host antimicrobial response and suppression of microbe dissemination following peritoneal infection.PLoS Pathog2022
33325565Genome-wide analysis of in vivo CcpA binding with and without its key co-factor HPr in the major human pathogen group A Streptococcus.Mol Microbiol2021
33510265Host-directed therapy in foals can enhance functional innate immunity and reduce severity of Rhodococcus equi pneumonia.Sci Rep2021
33613497Collagen Binding Proteins of Gram-Positive Pathogens.Front Microbiol2021
34093507Editorial: Cell Surface Proteins of Gram-Positive Pathogenic Bacteria.Front Microbiol2021
34340548vhp Is a Fibrinogen-Binding Protein Related to vWbp in Staphylococcus aureus.mBio2021
33406160A type VII secretion system of Streptococcus gallolyticus subsp. gallolyticus contributes to gut colonization and the development of colon tumors.PLoS Pathog2021
33443167Host fibrinogen drives antimicrobial function in <i>Staphylococcus aureus</i> peritonitis through bacterial-mediated prothrombin activation.Proc Natl Acad Sci U S A2021
32071265Staphylococcus epidermidis MSCRAMM SesJ Is Encoded in Composite Islands.mBio2020
30607644Elucidation of Endothelial Cell Hemostatic Regulation with Integrin-Targeting Hydrogels.Ann Biomed Eng2019
31216354Host-specialized fibrinogen-binding by a bacterial surface protein promotes biofilm formation and innate immune evasion.PLoS Pathog2019
31406152Fibrinogen binding is affected by amino acid substitutions in C-terminal repeat region of fibronectin binding protein A.Sci Rep2019
31041195The Complex Fibrinogen Interactions of the <i>Staphylococcus aureus</i> Coagulases.Front Cell Infect Microbiol2019
29761640Influence of collagen-based integrin α<sub>1</sub> and α<sub>2</sub> mediated signaling on human mesenchymal stem cell osteogenesis in three dimensional contexts.J Biomed Mater Res A2018
33435015Collagen-Mimetic Proteins with Tunable Integrin Binding Sites for Vascular Graft Coatings.ACS Biomater Sci Eng2018
28400484Amino acid polymorphisms in the fibronectin-binding repeats of fibronectin-binding protein A affect bond strength and fibronectin conformation.J Biol Chem2017
28218444Evaluation of late outgrowth endothelial progenitor cell and umbilical vein endothelial cell responses to thromboresistant collagen-mimetic hydrogels.J Biomed Mater Res A2017
26733070Coagulase and Efb of Staphylococcus aureus Have a Common Fibrinogen Binding Motif.mBio2016
27789272Lessons from the Crystal Structure of the S. aureus Surface Protein Clumping Factor A in Complex With Tefibazumab, an Inhibiting Monoclonal Antibody.EBioMedicine2016
27199900A Novel MSCRAMM Subfamily in Coagulase Negative Staphylococcal Species.Front Microbiol2016
27434228Allosteric Regulation of Fibronectin/α5β1 Interaction by Fibronectin-Binding MSCRAMMs.PLoS One2016
26808924Borrelia burgdorferi BBK32 Inhibits the Classical Pathway by Blocking Activation of the C1 Complement Complex.PLoS Pathog2016
25560615The BBA33 lipoprotein binds collagen and impacts Borrelia burgdorferi pathogenesis.Mol Microbiol2015
28989705Collagen-mimetic hydrogels promote human endothelial cell adhesion, migration and phenotypic maturation.J Mater Chem B2015
26244101Chronic Wound Dressings Based on Collagen-Mimetic Proteins.Adv Wound Care (New Rochelle)2015
26371130The fibronectin-binding protein Fnm contributes to adherence to extracellular matrix components and virulence of Enterococcus faecium.Infect Immun2015
26228483Mice expressing a mutant form of fibrinogen that cannot support fibrin formation exhibit compromised antimicrobial host defense.Blood2015
25512313The identification and functional characterization of WxL proteins from Enterococcus faecium reveal surface proteins involved in extracellular matrix interactions.J Bacteriol2015
24336184Adhesion, invasion and evasion: the many functions of the surface proteins of Staphylococcus aureus.Nat Rev Microbiol2014
25115812SdrC induces staphylococcal biofilm formation through a homophilic interaction.Mol Microbiol2014
24732634A multifunctional streptococcal collagen-mimetic protein coating prevents bacterial adhesion and promotes osteoid formation on titanium.Acta Biomater2014
24935249Endothelial cell response to chemical, biological, and physical cues in bioactive hydrogels.Tissue Eng Part A2014
23299312Genetic elimination of the binding motif on fibrinogen for the S. aureus virulence factor ClfA improves host survival in septicemia.Blood2013
24348255Phagocytosis escape by a Staphylococcus aureus protein that connects complement and coagulation proteins at the bacterial surface.PLoS Pathog2013
23720782Collagen-binding microbial surface components recognizing adhesive matrix molecule (MSCRAMM) of Gram-positive bacteria inhibit complement activation via the classical pathway.J Biol Chem2013
23758437Bioactive hydrogels with enhanced initial and sustained cell interactions.Biomacromolecules2013
23551253Expression of the collagen adhesin ace by Enterococcus faecalis strain OG1RF is not repressed by Ers but requires the Ers box.FEMS Microbiol Lett2013
22142564Multilayer vascular grafts based on collagen-mimetic proteins.Acta Biomater2012
23019346A newly identified enhancer element responsible for type II collagen gene expression.J Biochem2012
22865854Targeted protein engineering provides insights into binding mechanism and affinities of bacterial collagen adhesins.J Biol Chem2012
22615182Augmenting the articular cartilage-implant interface: Functionalizing with a collagen adhesion protein.J Biomed Mater Res A2012
21247890Binding of Efb from Staphylococcus aureus to fibrinogen blocks neutrophil adherence.J Biol Chem2011
21854463Bioluminescent imaging of Borrelia burgdorferi in vivo demonstrates that the fibronectin-binding protein BBK32 is required for optimal infectivity.Mol Microbiol2011
21576333Genomic and surface proteomic analysis of the canine pathogen Staphylococcus pseudintermedius reveals proteins that mediate adherence to the extracellular matrix.Infect Immun2011
21543319Structural and biochemical characterization of Staphylococcus aureus clumping factor B/ligand interactions.J Biol Chem2011
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Collaborators

Xiaowen Liang
The University of Texas MD Anderson Cancer Center
Co-authored papers 22
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The University of Texas M.D. Anderson Cancer Center
Co-authored papers 7
George M Weinstock
The Genome Center at Washington University, Washington University School of Medicine
Co-authored papers 4
Chris Mackenzie
McGovern Medical School
Co-authored papers 3
Iain D Campbell
University of Oxford
Co-authored papers 3
Wadih Arap
Rutgers Cancer Institute of New Jersey
Co-authored papers 2
Christer Busch
Uppsala University
Co-authored papers 2
Jung Hyeob Roh
Co-authored papers 2
Renata Pasqualini
Rutgers Cancer Institute of New Jersey
Co-authored papers 2
Even Fossum
Oslo University Hospital
Co-authored papers 1
Frank B Furnari
University of California San Diego
Co-authored papers 1
Juri G Gelovani
Karmanos Cancer Institute (KCI), Wayne State University
Co-authored papers 1
Martin J Humphries
University of Manchester
Co-authored papers 1
Kenneth Aldape
National Cancer Institute
Co-authored papers 1
Michael G Ozawa
Stanford University School of Medicine
Co-authored papers 1
Catherine A Moya
Co-authored papers 1
David W Threadgill
College Station
Co-authored papers 1
Kari Alitalo
Wihuri Research Institute
Co-authored papers 1
Mian M Alauddin
The University of Texas MD Anderson Cancer Center
Co-authored papers 1
Frederick F Lang
The University of Texas M.D. Anderson Cancer Center
Co-authored papers 1
Raymond C Harris
Vanderbilt University Medical Center
Co-authored papers 1
J??rgen Haas
University of Edinburgh
Co-authored papers 1
Leo G Flores
The University of Texas MD Anderson Cancer Center
Co-authored papers 1
Gregory N Fuller
MD Anderson Cancer Center
Co-authored papers 1
Vance G Fowler
Duke University School of Medicine
Co-authored papers 1
Batu K Sharma-Kuinkel
Duke University Medical Center
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Steffen Gay
Co-authored papers 1
Oliver B??gler
American Association for Cancer Research, Henry Ford Hospital, Ludwig Institute for Cancer Research, National Cancer Institute, Salk Institute for Biological Studies, University of Cambridge, University of Texas MD Anderson Cancer Center, Virginia Commonwealth University
Co-authored papers 1
Zhengfang Yi
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Release 1.2