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Author Details

Jason Fangusaro
2004
95
35
PMIDPaper TitleJournal TitlePublished Year
37715730Indoximod-based chemo-immunotherapy for pediatric brain tumors: A first-in-children phase I trial.Neuro Oncol2024
37944912Pediatric low-grade glioma: State-of-the-art and ongoing challenges.Neuro Oncol2024
37526549Phase I trial of panobinostat in children with diffuse intrinsic pontine glioma: A report from the Pediatric Brain Tumor Consortium (PBTC-047).Neuro Oncol2023
36335802The children's brain tumor network (CBTN) - Accelerating research in pediatric central nervous system tumors through collaboration and open science.Neoplasia2023
37738646Optimizing preclinical pediatric low-grade glioma models for meaningful clinical translation.Neuro Oncol2023
37046770Evaluating Focal Areas of Signal Intensity (FASI) in Children with Neurofibromatosis Type-1 (NF1) Treated with Selumetinib on Pediatric Brain Tumor Consortium (PBTC)-029B.2023
37534382Children's Oncology Group's 2023 blueprint for research: Central nervous system tumors.Pediatr Blood Cancer2023
35210278ADC Histogram Analysis of Pediatric Low-Grade Glioma Treated with Selumetinib: A Report from the Pediatric Brain Tumor Consortium.2022
35489353Imaging response assessment for CNS germ cell tumours: consensus recommendations from the European Society for Paediatric Oncology Brain Tumour Group and North American Children's Oncology Group.Lancet Oncol2022
36335782Paediatric Strategy Forum for medicinal product development in mitogen-activated protein kinase pathway inhibitors: ACCELERATE in collaboration with the European Medicines Agency with participation of the Food and Drug Administration.Eur J Cancer2022
36056180Nervous system (NS) Tumors in Cancer Predisposition Syndromes.2022
35788692MEK inhibitors for neurofibromatosis type 1 manifestations: Clinical evidence and consensus.Neuro Oncol2022
35544730Comprehensive Genomic Profiling of High-Risk Pediatric Cancer Patients Has a Measurable Impact on Clinical Care.JCO Precis Oncol2022
35977349Clinical Activity of Mitogen-Activated Protein Kinase-Targeted Therapies in Patients With Non-V600 BRAF-Mutant Tumors.JCO Precis Oncol2022
34990779A Phase 2 Trial of Response-Based Radiation Therapy for Localized Central Nervous System Germ Cell Tumors: Patterns of Failure and Radiation Dosimetry for Nongerminomatous Germ Cell Tumors.Int J Radiat Oncol Biol Phys2022
35307742Corrigendum to: LTBK-01. Updates On The Phase Ii And Re-treatment Study Of AZD6244 (Selumetinib) For Children With Recurrent Or Refractory Pediatric Low Grade Glioma: A Pediatric Brain Tumor Consortium (PBTC) Study.Neuro Oncol2022
35218656Pattern of treatment failures in patients with central nervous system non-germinomatous germ cell tumors (CNS-NGGCT): A pooled analysis of clinical trials.Neuro Oncol2022
34850169Phase II trial of response-based radiation therapy for patients with localized germinoma: a Children's Oncology Group study.Neuro Oncol2022
34591650Multicenter Analysis of Genomically Targeted Single Patient Use Requests for Pediatric Neoplasms.Journal of Clinical Oncology2021
34168987Phase 2 Study of Pomalidomide (CC-4047) Monotherapy for Children and Young Adults With Recurrent or Progressive Primary Brain Tumors.Front Oncol2021
33631016A phase II trial of selumetinib in children with recurrent optic pathway and hypothalamic low-grade glioma without NF1: a Pediatric Brain Tumor Consortium study.Neuro Oncol2021
33583506Neonatal Central Nervous System Tumors.Clinics in Perinatology2021
33354735Clinical Pharmacokinetics and Pharmacodynamics of Selumetinib.Clinical Pharmacokinetics2021
33025730Phase 1 study of pomalidomide in children with recurrent, refractory, and progressive central nervous system tumors: A Pediatric Brain Tumor Consortium trial.Pediatr Blood Cancer2021
33278109Advances in the classification and treatment of pediatric brain tumors.Current Opinion in Pediatrics2021
32502457Response assessment in paediatric low-grade glioma: recommendations from the Response Assessment in Pediatric Neuro-Oncology (RAPNO) working group.Lancet Oncol2020
32187454Pineoblastoma in children less than six years of age: The Head Start I, II, and III experience.Pediatr Blood Cancer2020
32241771Advanced ADC Histogram, Perfusion, and Permeability Metrics Show an Association with Survival and Pseudoprogression in Newly Diagnosed Diffuse Intrinsic Pontine Glioma: A Report from the Pediatric Brain Tumor Consortium.AJNR Am J Neuroradiol2020
32055852Implications of new understandings of gliomas in children and adults with NF1: report of a consensus conference.Neuro Oncol2020
32289265The "Risk" in Pediatric Low-Grade Glioma.Cancer Cell2020
31545689Phase II Trial of Response-Based Radiation Therapy for Patients With Localized CNS Nongerminomatous Germ Cell Tumors: A Children's Oncology Group Study.J Clin Oncol2019
30531227Management of pediatric low-grade glioma.Current Opinion in Pediatrics2019
31287992A C19MC-LIN28A-MYCN Oncogenic Circuit Driven by Hijacked Super-enhancers Is a Distinct Therapeutic Vulnerability in ETMRs: A Lethal Brain Tumor.Cancer Cell2019
30670636Transcriptional repressor REST drives lineage stage-specific chromatin compaction at <i>Ptch1</i> and increases AKT activation in a mouse model of medulloblastoma.Sci Signal2019
30997512Improved neuropsychological outcomes following proton therapy relative to X-ray therapy for pediatric brain tumor patients.Neuro Oncol2019
31151904Selumetinib in paediatric patients with BRAF-aberrant or neurofibromatosis type 1-associated recurrent, refractory, or progressive low-grade glioma: a multicentre, phase 2 trial.Lancet Oncol2019
29741745Prospective feasibility and safety assessment of surgical biopsy for patients with newly diagnosed diffuse intrinsic pontine glioma.Neuro Oncol2018
29016845Pediatric low-grade gliomas: next biologically driven steps.Neuro Oncol2018
27683733Pediatric low-grade gliomas: implications of the biologic era.Neuro Oncol2017
28733870Rethinking childhood ependymoma: a retrospective, multi-center analysis reveals poor long-term overall survival.J Neurooncol2017
28689260Extended diffusion weighted magnetic resonance imaging with two-compartment and anomalous diffusion models for differentiation of low-grade and high-grade brain tumors in pediatric patients.Neuroradiology2017
28339824A phase I trial of the MEK inhibitor selumetinib (AZD6244) in pediatric patients with recurrent or refractory low-grade glioma: a Pediatric Brain Tumor Consortium (PBTC) study.Neuro Oncol2017
28326681Population Pharmacokinetics of Selumetinib and Its Metabolite N-desmethyl-selumetinib in Adult Patients With Advanced Solid Tumors and Children With Low-Grade Gliomas.CPT: Pharmacometrics and Systems Pharmacology2017
28879377Erratum to: Extended diffusion weighted magnetic resonance imaging with two-compartment and anomalous diffusion models for differentiation of low-grade and high-grade brain tumors in pediatric patients.Neuroradiology2017
29435175REST upregulates gremlin to modulate diffuse intrinsic pontine glioma vasculature.Oncotarget2017
28011926Evaluation of age-dependent treatment strategies for children and young adults with pineoblastoma: analysis of pooled European Society for Paediatric Oncology (SIOP-E) and US Head Start data.Neuro Oncol2017
27510726Phase II trial of pegylated interferon alfa-2b in young patients with neurofibromatosis type 1 and unresectable plexiform neurofibromas.Neuro Oncol2017
27622066Improving vaccine efficacy against malignant glioma.Oncoimmunology2016
27187113Severe Radiation Necrosis Successfully Treated With Bevacizumab in an Infant with Low-Grade Glioma and Tumor-Associated Intractable Trigeminal Neuralgia.Pediatr Blood Cancer2016
27425592The deubiquitylase USP37 links REST to the control of p27 stability and cell proliferation.Oncogene2016
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