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Author Details
Full Name
David Baker
Affiliation
University of Washington
ORCID
Career Start Year
1988
Papers
687
H Index
148
Expertise
CM4AI Collaborator
Andrej Sali (CM4AI)
PMID
Paper Title
Journal Title
Published Year
37996753
Accurate prediction of protein-nucleic acid complexes using RoseTTAFoldNA.
Nat Methods
2024
37996753
Accurate prediction of protein-nucleic acid complexes using RoseTTAFoldNA.
Nat Methods
2024
36316485
A split, conditionally active mimetic of IL-2 reduces the toxicity of systemic cytokine therapy.
Nat Biotechnol
2023
36316485
A split, conditionally active mimetic of IL-2 reduces the toxicity of systemic cytokine therapy.
Nat Biotechnol
2023
37939083
In vivo selection of synthetic nucleocapsids for tissue targeting.
Proc Natl Acad Sci U S A
2023
37845322
Accurate computational design of three-dimensional protein crystals.
Nat Mater
2023
37667012
Precisely patterned nanofibres made from extendable protein multiplexes.
Nat Chem
2023
37662224
<i>De novo</i> design of buttressed loops for sculpting protein functions.
bioRxiv
2023
37590357
Design of stimulus-responsive two-state hinge proteins.
Science
2023
37582367
Single-cell census of human tooth development enables generation of human enamel.
Dev Cell
2023
37577478
Rapid and automated design of two-component protein nanomaterials using ProteinMPNN.
bioRxiv
2023
37794071
Nanoparticle display of prefusion coronavirus spike elicits S1-focused cross-reactive antibody response against diverse coronavirus subgenera.
Nat Commun
2023
37790440
Computational design of sequence-specific DNA-binding proteins.
bioRxiv
2023
37632837
De novo design of monomeric helical bundles for pH-controlled membrane lysis.
Protein Sci
2023
37704610
De novo design of highly selective miniprotein inhibitors of integrins αvβ6 and αvβ8.
Nat Commun
2023
37873412
Single-cell signaling analysis reveals that Major Vault Protein facilitates RasG12C inhibitor resistance.
bioRxiv
2023
37781607
Designed Endocytosis-Triggering Proteins mediate Targeted Degradation.
bioRxiv
2023
37781598
<i>De novo</i> designed Hsp70 activator dissolves intracellular condensates.
bioRxiv
2023
37695922
Zero-shot mutation effect prediction on protein stability and function using RoseTTAFold.
Protein Sci
2023
38052802
Design and structural validation of peptide-drug conjugate ligands of the kappa-opioid receptor.
Nat Commun
2023
37774705
Synthetic Par polarity induces cytoskeleton asymmetry in unpolarized mammalian cells.
Cell
2023
37094170
Exploiting conformational dynamics to modulate the function of designed proteins.
Proc Natl Acad Sci U S A
2023
37341421
Design of Heme Enzymes with a Tunable Substrate Binding Pocket Adjacent to an Open Metal Coordination Site.
J Am Chem Soc
2023
37149653
Improving de novo protein binder design with deep learning.
Nat Commun
2023
37027789
Macrocyclic Octapeptide Binding and Inferences on Protein Substrate Binding to Histone Deacetylase 6.
ACS Chem Biol
2023
37024727
Design of cell-type-specific hyperstable IL-4 mimetics via modular de novo scaffolds.
Nat Chem Biol
2023
36897987
De novo design of small beta barrel proteins.
Proc Natl Acad Sci U S A
2023
36828268
ModelCIF: An Extension of PDBx/mmCIF Data Representation for Computed Structure Models.
J Mol Biol
2023
37333359
Blueprinting expandable nanomaterials with standardized protein building blocks.
bioRxiv
2023
37398374
Hierarchical design of pseudosymmetric protein nanoparticles.
bioRxiv
2023
37398153
<i>De novo</i> design of highly selective miniprotein inhibitors of integrins αvβ6 and αvβ8.
bioRxiv
2023
37398067
De novo design of modular protein hydrogels with programmable intra- and extracellular viscoelasticity.
bioRxiv
2023
37079676
Top-down design of protein architectures with reinforcement learning.
Science
2023
36888664
Improving the secretion of designed protein assemblies through negative design of cryptic transmembrane domains.
Proc Natl Acad Sci U S A
2023
36813896
De novo design of luciferases using deep learning.
Nature
2023
36493355
Reshaping de Novo Protein Switches into Bioresponsive Materials for Biomarker, Toxin, and Viral Detection.
Adv Mater
2023
37131790
De novo design of energy transfer proteins housing excitonically coupled chlorophyll special pairs.
Res Sq
2023
37131615
Computational design of non-porous, pH-responsive antibody nanoparticles.
bioRxiv
2023
36807264
The ϿPA3 phage nucleus is enclosed by a self-assembling 2D crystalline lattice.
Nat Commun
2023
36627259
Design of Diverse Asymmetric Pockets in <i>De Novo</i> Homo-oligomeric Proteins.
Biochemistry
2023
37066191
Stepwise design of pseudosymmetric protein hetero-oligomers.
bioRxiv
2023
36802421
Peptide-binding specificity prediction using fine-tuned protein structure prediction networks.
Proc Natl Acad Sci U S A
2023
36798377
Massively parallel protein-protein interaction measurement by sequencing (MP3-seq) enables rapid screening of protein heterodimers.
bioRxiv
2023
37433327
De novo design of protein structure and function with RFdiffusion.
Nature
2023
36993355
Modulation of FGF pathway signaling and vascular differentiation using designed oligomeric assemblies.
bioRxiv
2023
37503272
Hierarchical design of pseudosymmetric protein nanoparticles.
Res Sq
2023
37667012
Precisely patterned nanofibres made from extendable protein multiplexes.
Nat Chem
2023
37632837
De novo design of monomeric helical bundles for pH-controlled membrane lysis.
Protein Sci
2023
37662224
<i>De novo</i> design of buttressed loops for sculpting protein functions.
bioRxiv
2023
37590357
Design of stimulus-responsive two-state hinge proteins.
Science
2023
1 - 50 of 1,374
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