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Author Details
Full Name
Arndt Borkhardt
Affiliation
Hematology and Clinical Immunology, Heinrich Heine University Dusseldorf
ORCID
Career Start Year
1992
Papers
403
H Index
65
Expertise
CM4AI Collaborator
Antoine Forget (CM4AI)
PMID
Paper Title
Journal Title
Published Year
37776287
Optical genome mapping identifies structural variants in potentially new cancer predisposition candidate genes in pediatric cancer patients.
Int J Cancer
2024
37945316
Biallelic inactivation of the NF1 tumour suppressor gene in juvenile myelomonocytic leukaemia: Genetic evidence of driver function and implications for diagnostic workup.
Br J Haematol
2024
37776287
Optical genome mapping identifies structural variants in potentially new cancer predisposition candidate genes in pediatric cancer patients.
Int J Cancer
2024
37945316
Biallelic inactivation of the NF1 tumour suppressor gene in juvenile myelomonocytic leukaemia: Genetic evidence of driver function and implications for diagnostic workup.
Br J Haematol
2024
34196794
Results from a pilot study on the oral microbiome in children and adolescents with chronic nonbacterial osteomyelitis.
Z Rheumatol
2023
35484663
B-cell precursor leukemias with <i>MYC</i>-rearrangement come into the limelight.
Haematologica
2023
36332176
EBV-driven lymphoid neoplasms associated with pediatric ALL maintenance therapy.
Blood
2023
35537032
Noncancer-related Secondary Findings in a Cohort of 231 Children With Cancer and Their Parents.
J Pediatr Hematol Oncol
2023
37670804
AP-1 Transcription Factor Complex Members <i>FOSB</i> and <i>FOS</i> are Linked With CNS Infiltration and Inferior Prognosis in Childhood T-ALL.
Hemasphere
2023
37582744
Unleashing T cell anti-tumor immunity: new potential for 5-Nonloxytryptamine as an agent mediating MHC-I upregulation in tumors.
Mol Cancer
2023
37717691
High-throughput screening as a drug repurposing strategy for poor outcome subgroups of pediatric B-cell precursor Acute Lymphoblastic Leukemia.
Biochem Pharmacol
2023
38057328
Co-targeting HSP90 alpha and CDK7 overcomes resistance against HSP90 inhibitors in BCR-ABL1+ leukemia cells.
Cell Death Dis
2023
37158619
Temporal patterns of childhood cancer survival 1991 to 2016: A nationwide register-study based on data from the German Childhood Cancer Registry.
Int J Cancer
2023
37469802
Optical Genome Mapping Identifies Novel Recurrent Structural Alterations in Childhood <i>ETV6::RUNX1+</i> and High Hyperdiploid Acute Lymphoblastic Leukemia.
Hemasphere
2023
37033933
Arenaviruses: Old viruses present new solutions for cancer therapy.
Front Immunol
2023
37149759
A clinical screening tool to detect genetic cancer predisposition in pediatric oncology shows high sensitivity but can miss a substantial percentage of affected children.
Genet Med
2023
36824296
Resolving inherited and <i>de novo</i> germline predisposing sequence variants by means of whole exome trio analyses in childhood hematological malignancies.
Front Pediatr
2023
36647327
Reply to: Comments on "The CHK2 kinase is recurrently mutated and functionally impaired in the germline of pediatric cancer patients".
Int J Cancer
2023
36764385
Functional damaging germline variants in ETV6, IKZF1, PAX5 and RUNX1 predisposing to B-cell precursor acute lymphoblastic leukemia.
Eur J Med Genet
2023
36639636
Chemotherapy-related hyperbilirubinemia in pediatric acute lymphoblastic leukemia: a genome-wide association study from the AIEOP-BFM ALL study group.
J Exp Clin Cancer Res
2023
36639156
Tacedinaline (CI-994), a class I HDAC inhibitor, targets intrinsic tumor growth and leptomeningeal dissemination in MYC-driven medulloblastoma while making them susceptible to anti-CD47-induced macrophage phagocytosis via NF-kB-TGM2 driven tumor inflammation.
J Immunother Cancer
2023
37448856
Development of the first geldanamycin-based HSP90 degraders.
Front Chem
2023
37439330
Worms on stage.
Haematologica
2023
36741356
Cytokine Hyperresponsiveness in Children With ETV6::RUNX1-positive Acute Lymphoblastic Leukemia After Challenge With Common Pathogens.
Hemasphere
2023
37304931
Definition and Prognostic Value of Ph-like and IKZF1plus Status in Children With Down Syndrome and B-cell Precursor Acute Lymphoblastic Leukemia.
Hemasphere
2023
36468172
The CHK2 kinase is recurrently mutated and functionally impaired in the germline of pediatric cancer patients.
Int J Cancer
2023
37046711
Pediatric Patients with Stage IV Rhabdomyosarcoma Significantly Benefit from Long-Term Maintenance Therapy: Results of the CWS-IV 2002 and the CWS DOK IV 2004-Trials.
Cancers (Basel)
2023
34196794
Results from a pilot study on the oral microbiome in children and adolescents with chronic nonbacterial osteomyelitis.
Z Rheumatol
2023
37670804
AP-1 Transcription Factor Complex Members <i>FOSB</i> and <i>FOS</i> are Linked With CNS Infiltration and Inferior Prognosis in Childhood T-ALL.
Hemasphere
2023
37717691
High-throughput screening as a drug repurposing strategy for poor outcome subgroups of pediatric B-cell precursor Acute Lymphoblastic Leukemia.
Biochem Pharmacol
2023
37582744
Unleashing T cell anti-tumor immunity: new potential for 5-Nonloxytryptamine as an agent mediating MHC-I upregulation in tumors.
Mol Cancer
2023
38057328
Co-targeting HSP90 alpha and CDK7 overcomes resistance against HSP90 inhibitors in BCR-ABL1+ leukemia cells.
Cell Death Dis
2023
35537032
Noncancer-related Secondary Findings in a Cohort of 231 Children With Cancer and Their Parents.
J Pediatr Hematol Oncol
2023
35484663
B-cell precursor leukemias with <i>MYC</i>-rearrangement come into the limelight.
Haematologica
2023
37158619
Temporal patterns of childhood cancer survival 1991 to 2016: A nationwide register-study based on data from the German Childhood Cancer Registry.
Int J Cancer
2023
37149759
A clinical screening tool to detect genetic cancer predisposition in pediatric oncology shows high sensitivity but can miss a substantial percentage of affected children.
Genet Med
2023
37046711
Pediatric Patients with Stage IV Rhabdomyosarcoma Significantly Benefit from Long-Term Maintenance Therapy: Results of the CWS-IV 2002 and the CWS DOK IV 2004-Trials.
Cancers (Basel)
2023
37448856
Development of the first geldanamycin-based HSP90 degraders.
Front Chem
2023
37469802
Optical Genome Mapping Identifies Novel Recurrent Structural Alterations in Childhood <i>ETV6::RUNX1+</i> and High Hyperdiploid Acute Lymphoblastic Leukemia.
Hemasphere
2023
37439330
Worms on stage.
Haematologica
2023
37304931
Definition and Prognostic Value of Ph-like and IKZF1plus Status in Children With Down Syndrome and B-cell Precursor Acute Lymphoblastic Leukemia.
Hemasphere
2023
37033933
Arenaviruses: Old viruses present new solutions for cancer therapy.
Front Immunol
2023
36647327
Reply to: Comments on "The CHK2 kinase is recurrently mutated and functionally impaired in the germline of pediatric cancer patients".
Int J Cancer
2023
36741356
Cytokine Hyperresponsiveness in Children With ETV6::RUNX1-positive Acute Lymphoblastic Leukemia After Challenge With Common Pathogens.
Hemasphere
2023
36468172
The CHK2 kinase is recurrently mutated and functionally impaired in the germline of pediatric cancer patients.
Int J Cancer
2023
36639636
Chemotherapy-related hyperbilirubinemia in pediatric acute lymphoblastic leukemia: a genome-wide association study from the AIEOP-BFM ALL study group.
J Exp Clin Cancer Res
2023
36639156
Tacedinaline (CI-994), a class I HDAC inhibitor, targets intrinsic tumor growth and leptomeningeal dissemination in MYC-driven medulloblastoma while making them susceptible to anti-CD47-induced macrophage phagocytosis via NF-kB-TGM2 driven tumor inflammation.
J Immunother Cancer
2023
36764385
Functional damaging germline variants in ETV6, IKZF1, PAX5 and RUNX1 predisposing to B-cell precursor acute lymphoblastic leukemia.
Eur J Med Genet
2023
36824296
Resolving inherited and <i>de novo</i> germline predisposing sequence variants by means of whole exome trio analyses in childhood hematological malignancies.
Front Pediatr
2023
36332176
EBV-driven lymphoid neoplasms associated with pediatric ALL maintenance therapy.
Blood
2023
1 - 50 of 806
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Collaborators
Ute Fischer
Hematology and Clinical Immunology, Heinrich Heine University Dusseldorf
Co-authored papers
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Michaela Kuhlen
Co-authored papers
50
Michael Gombert
Hematology and Clinical Immunology, Heinrich-Heine University Dusseldorf
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32
Thomas Klingebiel
Co-authored papers
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and Clinical Immunology, Heinrich Heine University, University Hospital Dusseldorf
Co-authored papers
17
Daniel Picard
Groupe Hospitalier Universitaire Pitie-Salpetriere
Co-authored papers
17
Markus Metzler
University Hospital Erlangen
Co-authored papers
16
Birgit Burkhardt
Co-authored papers
16
Cornelia Eckert
Co-authored papers
14
Guido Reifenberger
Heinrich Heine University
Co-authored papers
12
Aleksandra A Pandyra
Hematology and Clinical Immunology, Heinrich-Heine University Dusseldorf
Co-authored papers
11
Alice C McHardy
Computational Biology of Infection Research, Helmholtz Centre for Infection Research
Co-authored papers
11
Reiner Siebert
Co-authored papers
11
Ewa Koscielniak
Co-authored papers
9
Uta Dirksen
University Hospital Essen, West German Cancer Center
Co-authored papers
9
Peter Lichter
German Cancer Research Center (DKFZ)
Co-authored papers
9
Stefan M Pfister
Hopp Children's Cancer Center Heidelberg (KiTZ)
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9
Nan Qin
and Clinical Immunology, Heinrich Heine University, University Hospital Dusseldorf
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Jasmin Bartl
German Cancer Research Center (DKFZ)
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Andreas E Kulozik
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Angelika Eggert
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Roland Eils
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