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Author Details

Benoit G Bruneau
Gladstone Institutes of Cardiovascular Disease, Gladstone Institutes
1994
137
63
Nevan J Krogan (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36736300Graded mesoderm assembly governs cell fate and morphogenesis of the early mammalian heart.Cell2023
36994838A Mesp1-dependent developmental breakpoint in transcriptional and epigenomic specification of early cardiac precursors.Development2023
36736300Graded mesoderm assembly governs cell fate and morphogenesis of the early mammalian heart.Cell2023
37419111Spatial and temporal organization of the genome: Current state and future aims of the 4D nucleome project.Mol Cell2023
37419111Spatial and temporal organization of the genome: Current state and future aims of the 4D nucleome project.Mol Cell2023
36994838A Mesp1-dependent developmental breakpoint in transcriptional and epigenomic specification of early cardiac precursors.Development2023
35082446Brahma safeguards canalization of cardiac mesoderm differentiation.Nature2022
35967929Cell Layers: uncovering clustering structure in unsupervised single-cell transcriptomic analysis.Bioinform Adv2022
35835508Modeling congenital heart disease: lessons from mice, hPSC-based models, and organoids.Genes Dev2022
35896549Targeting transcription in heart failure via CDK7/12/13 inhibition.Nat Commun2022
35938400Transcription Factor GATA4 Regulates Cell Type-Specific Splicing Through Direct Interaction With RNA in Human Induced Pluripotent Stem Cell-Derived Cardiac Progenitors.Circulation2022
35182466Transcription factor protein interactomes reveal genetic determinants in heart disease.Cell2022
35082446Brahma safeguards canalization of cardiac mesoderm differentiation.Nature2022
35835508Modeling congenital heart disease: lessons from mice, hPSC-based models, and organoids.Genes Dev2022
35938400Transcription Factor GATA4 Regulates Cell Type-Specific Splicing Through Direct Interaction With RNA in Human Induced Pluripotent Stem Cell-Derived Cardiac Progenitors.Circulation2022
35967929Cell Layers: uncovering clustering structure in unsupervised single-cell transcriptomic analysis.Bioinform Adv2022
35896549Targeting transcription in heart failure via CDK7/12/13 inhibition.Nat Commun2022
35182466Transcription factor protein interactomes reveal genetic determinants in heart disease.Cell2022
33318687WAPL maintains a cohesin loading cycle to preserve cell-type-specific distal gene regulation.Nat Genet2021
33557580Mechanisms of Congenital Heart Disease Caused by NAA15 Haploinsufficiency.Circ Res2021
33318687WAPL maintains a cohesin loading cycle to preserve cell-type-specific distal gene regulation.Nat Genet2021
34861147Co-emergence of cardiac and gut tissues promotes cardiomyocyte maturation within human iPSC-derived organoids.Cell Stem Cell2021
34725128Dissecting CTCF site function in a tense HoxD locus.Genes Dev2021
33557580Mechanisms of Congenital Heart Disease Caused by NAA15 Haploinsufficiency.Circ Res2021
34861147Co-emergence of cardiac and gut tissues promotes cardiomyocyte maturation within human iPSC-derived organoids.Cell Stem Cell2021
34725128Dissecting CTCF site function in a tense HoxD locus.Genes Dev2021
32487268Author Correction: Defining the relative and combined contribution of CTCF and CTCFL to genomic regulation.Genome Biol2020
32106109Salt-inducible kinase 1 maintains HDAC7 stability to promote pathologic cardiac remodeling.J Clin Invest2020
32393311Defining the relative and combined contribution of CTCF and CTCFL to genomic regulation.Genome Biol2020
32284594Transcriptional profiling and therapeutic targeting of oxidative stress in neuroinflammation.Nat Immunol2020
32487268Author Correction: Defining the relative and combined contribution of CTCF and CTCFL to genomic regulation.Genome Biol2020
32444692Cardiac natriuretic peptides.Nat Rev Cardiol2020
33154377Molecular basis of CTCF binding polarity in genome folding.Nat Commun2020
33087326The developing heart: from <i>The Wizard of Oz</i> to congenital heart disease.Development2020
33077913Regulation of single-cell genome organization into TADs and chromatin nanodomains.Nat Genet2020
32661365Author Correction: Transcriptional profiling and therapeutic targeting of oxidative stress in neuroinflammation.Nat Immunol2020
32106109Salt-inducible kinase 1 maintains HDAC7 stability to promote pathologic cardiac remodeling.J Clin Invest2020
33087326The developing heart: from <i>The Wizard of Oz</i> to congenital heart disease.Development2020
33077913Regulation of single-cell genome organization into TADs and chromatin nanodomains.Nat Genet2020
33154377Molecular basis of CTCF binding polarity in genome folding.Nat Commun2020
32661365Author Correction: Transcriptional profiling and therapeutic targeting of oxidative stress in neuroinflammation.Nat Immunol2020
32393311Defining the relative and combined contribution of CTCF and CTCFL to genomic regulation.Genome Biol2020
32284594Transcriptional profiling and therapeutic targeting of oxidative stress in neuroinflammation.Nat Immunol2020
32444692Cardiac natriuretic peptides.Nat Rev Cardiol2020
30660610A De Novo Shape Motif Discovery Algorithm Reveals Preferences of Transcription Factors for DNA Shape Beyond Sequence Motifs.Cell Syst2019
31601561Chromatin and epigenetics in development: a Special Issue.Development2019
31599722CTCF confers local nucleosome resiliency after DNA replication and during mitosis.Elife2019
31784461Minimal <i>in vivo</i> requirements for developmentally regulated cardiac long intergenic non-coding RNAs.Development2019
30595451Identifying cis Elements for Spatiotemporal Control of Mammalian DNA Replication.Cell2019
31522988RNA Interactions Are Essential for CTCF-Mediated Genome Organization.Mol Cell2019
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Collaborators

Gladstone Institutes San Francisco
Co-authored papers 15
Gladstone Institutes
Co-authored papers 15
Harvard Medical School
Co-authored papers 15
Brigham and Women's Hospital (Y.K.
Co-authored papers 15
Gladstone Institutes San Francisco
Co-authored papers 9
The Hospital for Sick Children
Co-authored papers 9
Gladstone Institute of Data Science and Biotechnology, Gladstone Institutes
Co-authored papers 8
Cardiovascular Research Institute, University of California san francisco
Co-authored papers 7
Co-authored papers 7
Gladstone Institutes
Co-authored papers 6
University of California San Francisco
Co-authored papers 5
Gladstone Institutes
Co-authored papers 5
Lawrence Berkeley National Laboratory
Co-authored papers 4
Gladstone Institutes San Francisco
Co-authored papers 3
Center for Developmental Biology, Anhui Agricultural University
Co-authored papers 3
Gladstone Institutes
Co-authored papers 3
University of Toronto
Co-authored papers 3
Gladstone Institutes of Cardiovascular Disease, Gladstone Institutes
Co-authored papers 3
Howard Hughes Medical Institute, Harvard Medical School
Co-authored papers 3
Gladstone Institutes
Co-authored papers 3
SAMRC/NHLS/UCT Molecular Mycobacteriology Research Unit, University of Cape Town
Co-authored papers 3
Institute of Data Science and Biotechnology, Gladstone Institutes
Co-authored papers 3
Boston Children's Hospital
Co-authored papers 3
Bakar Computational Health Sciences Institute, University of California san francisco
Co-authored papers 3
Quantitative Biosciences Institute (QBI), University of California san francisco
Co-authored papers 3
Gladstone Institutes San Francisco
Co-authored papers 3
Gladstone Institute of Cardiovascular Disease
Co-authored papers 3
University of California San Diego
Co-authored papers 2
Gladstone Institutes
Co-authored papers 2
Co-authored papers 2