Skip to Main Content

Author Details

Tom L Blundell
Heartand Lung Research Institute, University of Cambridge
1971
596
104
Andrej Sali (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36757665Chemical Validation of Mycobacterium tuberculosis Phosphopantetheine Adenylyltransferase Using Fragment Linking and CRISPR Interference.Angew Chem Int Ed Engl2023
37870477Structural and functional basis of inositol hexaphosphate stimulation of NHEJ through stabilization of Ku-XLF interaction.Nucleic Acids Res2023
37311458Cryo-EM structure of a DNA-PK trimer: higher order oligomerisation in NHEJ.Structure2023
37178506SARS-CoV-2 Omicron subvariant spike N405 unlikely to rapidly deamidate.Biochem Biophys Res Commun2023
36724784Two distinct long-range synaptic complexes promote different aspects of end processing prior to repair of DNA breaks by non-homologous end joining.Mol Cell2023
36915381<i>In silico</i> analyses of isoniazid and streptomycin resistance-associated mutations in <i>Mycobacterium tuberculosis</i>.Comput Struct Biotechnol J2023
36604499Human DNA-dependent protein kinase activation mechanism.Nat Struct Mol Biol2023
35229157Unheeded SARS-CoV-2 proteins? A deep look into negative-sense RNA.Brief Bioinform2022
35842061An Overview.Prog Biophys Mol Biol2022
35346669Structural Biology - Painting the Mechanistic Landscape of Biomolecules.J Mol Biol2022
35433835Using Structure-guided Fragment-Based Drug Discovery to Target <i>Pseudomonas aeruginosa</i> Infections in Cystic Fibrosis.Front Mol Biosci2022
35575289In silico analysis of mutations near S1/S2 cleavage site in SARS-CoV-2 spike protein reveals increased propensity of glycosylation in Omicron strain.J Med Virol2022
35656714Structural landscapes of PPI interfaces.Brief Bioinform2022
35712348Structural Characterization of <i>Mycobacterium abscessus</i> Phosphopantetheine Adenylyl Transferase Ligand Interactions: Implications for Fragment-Based Drug Design.Front Mol Biosci2022
36588539Structural biology - Painting the mechanistic landscape of biomolecules.Curr Res Struct Biol2022
36263813Catalytically inactive DNA ligase IV promotes DNA repair in living cells.Nucleic Acids Res2022
36008617Mycobacterium abscessus pathogenesis identified by phenogenomic analyses.Nat Microbiol2022
35163439Slipknot or Crystallographic Error: A Computational Analysis of the <i>Plasmodium falciparum</i> DHFR Structural Folds.Int J Mol Sci2022
35037462Development of Inhibitors of SAICAR Synthetase (PurC) from <i>Mycobacterium abscessus</i> Using a Fragment-Based Approach.ACS Infect Dis2022
35211117Are There Hidden Genes in DNA/RNA Vaccines?Front Immunol2022
35054954Searching for New Z-DNA/Z-RNA Binding Proteins Based on Structural Similarity to Experimentally Validated Zα Domain.Int J Mol Sci2022
35080396Discovery of Novel Inhibitors of Uridine Diphosphate-<i>N</i>-Acetylenolpyruvylglucosamine Reductase (MurB) from <i>Pseudomonas aeruginosa</i>, an Opportunistic Infectious Agent Causing Death in Cystic Fibrosis Patients.J Med Chem2022
34987222Structural insights into inhibitor regulation of the DNA repair protein DNA-PKcs.Nature2022
32327503Whole Exome Sequencing reveals NOTCH1 mutations in anaplastic large cell lymphoma and points to Notch both as a key pathway and a potential therapeutic target.Haematologica2021
33684422Editorial: Seventieth birthday Celebrations.Prog Biophys Mol Biol2021
33485852The resolution revolution in X-ray diffraction, Cryo-EM and other Technologies.Prog Biophys Mol Biol2021
33848149Three Simple Properties Explain Protein Stability Change upon Mutation.J Chem Inf Model2021
33511782SAP domain forms a flexible part of DNA aperture in Ku70/80.FEBS J2021
33926925Stepwise pathogenic evolution of <i>Mycobacterium abscessus</i>.Science2021
33632133A base measure of precision for protein stability predictors: structural sensitivity.BMC Bioinformatics2021
33798649Strategies for drug target identification in Mycobacterium leprae.Drug Discov Today2021
33798567The renaissance in biophysics and molecular biology enabled by the interface of DNA repair and replication with cancer.Prog Biophys Mol Biol2021
34869067Can the SARS-CoV-2 Spike Protein Bind Integrins Independent of the RGD Sequence?Front Cell Infect Microbiol2021
34520786The first resolution revolution in protein structure analysis: X-ray diffraction of polypeptide conformations and globular protein folds in 1950s and 1960s.Prog Biophys Mol Biol2021
34376561Using a synthetic switch to regulate insulin receptor activation.Proc Natl Acad Sci U S A2021
34353886Integrated human/SARS-CoV-2 metabolic models present novel treatment strategies against COVID-19.Life Sci Alliance2021
34352203Cryo-EM of NHEJ supercomplexes provides insights into DNA repair.Mol Cell2021
33939919Targeting <i>Mycobacterium tuberculosis</i> CoaBC through Chemical Inhibition of 4'-Phosphopantothenoyl-l-cysteine Synthetase (CoaB) Activity.ACS Infect Dis2021
34015821ProtCHOIR: a tool for proteome-scale generation of homo-oligomers.Brief Bioinform2021
34013350Utilizing graph machine learning within drug discovery and development.Brief Bioinform2021
34236667Deep Learning for Protein-Protein Interaction Site Prediction.Methods Mol Biol2021
34234921Predicted structural mimicry of spike receptor-binding motifs from highly pathogenic human coronaviruses.Comput Struct Biotechnol J2021
34139242From revolutionary technologies for understanding genes and proteins to a focus on new therapeutics.Prog Biophys Mol Biol2021
34026836Structure-Guided Computational Approaches to Unravel Druggable Proteomic Landscape of <i>Mycobacterium leprae</i>.Front Mol Biosci2021
34137435COSMIC Cancer Gene Census 3D database: understanding the impacts of mutations on cancer targets.Brief Bioinform2021
33285184Stages, scaffolds and strings in the spatial organisation of non-homologous end joining: Insights from X-ray diffraction and Cryo-EM.Prog Biophys Mol Biol2021
33337499Mechanism of efficient double-strand break repair by a long non-coding RNA.Nucleic Acids Res2021
33077952Dimers of DNA-PK create a stage for DNA double-strand break repair.Nat Struct Mol Biol2021
33420031Inhibiting Mycobacterium tuberculosis CoaBC by targeting an allosteric site.Nat Commun2021
33444527Using cryo-EM to understand antimycobacterial resistance in the catalase-peroxidase (KatG) from Mycobacterium tuberculosis.Structure2021
  • 1 - 50 of 596

Recommended Authors

Marc C Deller
Incyte Corporation
Career Start Year 2000
Number of shared co-authors 4
Jeffrey B Bonanno
Albert Einstein College of Medicine
Career Start Year 1999
Number of shared co-authors 5
David R Hall
Diamond Light Source Ltd, Harwell Science & Innovation Campus
Career Start Year 1998
Number of shared co-authors 5
Mallur S Madhusudhan
Indian Institute of Science Education and Research Pune
Career Start Year 1996
Number of shared co-authors 3
Roberto Sanchez
Department of Pharmacological Sciences, Icahn School of Medicine at Mount Sinai
Career Start Year 1996
Number of shared co-authors 4
Shira Albeck
Weizmann Institute of Science
Career Start Year 1996
Number of shared co-authors 5
Zihe Rao
Nankai University
Career Start Year 1995
Number of shared co-authors 5
Orly Dym
Weizmann Institute of Science
Career Start Year 1995
Number of shared co-authors 3
Clemens Vonrhein
Global Phasing Ltd
Career Start Year 1995
Number of shared co-authors 3
Gye Won Han
Bridge Institute, University of Southern California
Career Start Year 1991
Number of shared co-authors 4
Robert B Russell
Heidelberg University
Career Start Year 1991
Number of shared co-authors 4
Dietlind L Gerloff
Foundation for Applied Molecular Evolution (FfAME)
Career Start Year 1991
Number of shared co-authors 0
Wladek Minor
University of Virginia
Career Start Year 1989
Number of shared co-authors 7
Roland L Dunbrack
Fox Chase Cancer Center
Career Start Year 1989
Number of shared co-authors 8
Paul A Bates
The Francis Crick Institute
Career Start Year 1989
Number of shared co-authors 5
Steven C Almo
Albert Einstein College of Medicine
Career Start Year 1988
Number of shared co-authors 5
Miriam Eisenstein
Weizmann Institute of Science
Career Start Year 1988
Number of shared co-authors 5
Adam Godzik
University of California Riverside
Career Start Year 1987
Number of shared co-authors 11
Randy J Read
Cambridge Institute for Medical Research, University of Cambridge
Career Start Year 1982
Number of shared co-authors 5
Stephen K Burley
The State University of New Jersey
Career Start Year 1982
Number of shared co-authors 17
Ruth Nussinov
Sackler School of Medicine, Tel Aviv University
Career Start Year 1980
Number of shared co-authors 7
Chris Sander
Broad Institute of MIT and Harvard
Career Start Year 1979
Number of shared co-authors 2
Shoshana J Wodak
VIB-VUB Center for Structural Biology
Career Start Year 1975
Number of shared co-authors 8
George N Phillips
Rice University
Career Start Year 1974
Number of shared co-authors 6
Robert J Fletterick
University of California San Francisco
Career Start Year 1971
Number of shared co-authors 2
John Moult
Institute for Bioscience and Biotechnology Research
Career Start Year 1970
Number of shared co-authors 12
Andras Fiser
Albert Einstein College of Medicine
Career Start Year 1968
Number of shared co-authors 7
Sung-Hou Kim
University of California berkeley
Career Start Year 1967
Number of shared co-authors 4
Robert M Stroud
University of California San Francisco
Career Start Year 1965
Number of shared co-authors 7
David Eisenberg
university of california los angeles
Career Start Year 1963
Number of shared co-authors 7

Collaborators

Jonathan B Cooper
University College London
Co-authored papers 32
David F Burke
European Bioinformatics Institute (EMBL-EBI)
Co-authored papers 19
John P Overington
Institute of Cardiovascular Science, University College London
Co-authored papers 17
Mark S Johnson
Abo Akademi University
Co-authored papers 16
Andrej Sali (CM4AI)
University of California San Francisco
Co-authored papers 14
Ramanathan Sowdhamini
Indian Institute of Science
Co-authored papers 12
Paul I W de Bakker
Vertex Pharmaceuticals
Co-authored papers 11
Rodrigo Andres Floto
University of Cambridge
Co-authored papers 10
Mark A DePristo
Co-authored papers 9
Ashok R Venkitaraman
University of Cambridge, Hutchison Research Centre
Co-authored papers 9
Arun Prasad Pandurangan
Co-authored papers 9
Joel L Sussman
Weizmann Institute of Science
Co-authored papers 8
Carol V Robinson
University of Oxford
Co-authored papers 8
David S Moss
Institute of Structural and Molecular Biology, University of London
Co-authored papers 7
Sungsam Gong
Co-authored papers 7
Michael J E Sternberg
Imperial College London
Co-authored papers 7
Bhuvaneshwari Veerapandian
Center for Bioenergy, SASTRA Deemed University
Co-authored papers 7
Christine Humblet
Lilly Research Laboratories
Co-authored papers 6
Gordon V Louie
The Howard Hughes Medical Institute, Salk Institute for Biological Studies
Co-authored papers 6
Semin Lee
Ulsan National Institute of Science and Technology (UNIST)
Co-authored papers 6
Juan Fern??ndez-Recio
Instituto de Ciencias de la Vid y del Vino (ICVV-CSIC)
Co-authored papers 6
Zhan-yang Zhu
Stanford University
Co-authored papers 6
Dan Donnelly
University of Leeds
Co-authored papers 6
Stephen P Jackson
Mission Therapeutics Ltd. Glenn Berge Building
Co-authored papers 6
John A Tainer
The University of Texas MD Anderson Cancer Center
Co-authored papers 5
Julian Gough
Medical Research Council Laboratory of Molecular Biology
Co-authored papers 5
Dennis J Hoover
Synaptic Dynamics Inc.
Co-authored papers 5
Owen R Davies
Institute of Cell Biology, University of Edinburgh
Co-authored papers 4
Susan P Lees-Miller
University of Calgary, 0 Hospital Drive NW
Co-authored papers 4
Ian Sillitoe
University College London
Co-authored papers 4
Release 1.2