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Author Details

Robert F Siliciano
Johns Hopkins University School of Medicine
1978
351
100
Nevan J Krogan (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36602866Clonally expanded HIV-1 proviruses with 5'-leader defects can give rise to nonsuppressible residual viremia.J Clin Invest2023
37961482Last in first out: SIV proviruses seeded later in infection are harbored in short-lived CD4<sup>+</sup> T cells.bioRxiv2023
37961332Decoding Heterogenous Single-cell Perturbation Responses.bioRxiv2023
37844236Biphasic decay of intact SHIV genomes following initiation of antiretroviral therapy complicates analysis of interventions targeting the reservoir.Proc Natl Acad Sci U S A2023
37502921Assessing the impact of autologous neutralizing antibodies on viral rebound in postnatally SHIV-infected ART-treated infant rhesus macaques.bioRxiv2023
37126090Current HIV/SIV Reservoir Assays for Preclinical and Clinical Applications: Recommendations from the Experts 2022 NIAID Workshop Summary.AIDS Res Hum Retroviruses2023
37058141A cell-free antigen processing system informs HIV-1 epitope selection and vaccine design.J Exp Med2023
37379584HIV-Positive Liver Transplant Does not Alter the Latent Viral Reservoir in Recipients With Antiretroviral Therapy-Suppressed HIV.J Infect Dis2023
37236188Allogeneic immunity clears latent virus following allogeneic stem cell transplantation in SIV-infected ART-suppressed macaques.Immunity2023
37463049The latent reservoir of inducible, infectious HIV-1 does not decrease despite decades of antiretroviral therapy.J Clin Invest2023
36809762Antiretroviral therapy reveals triphasic decay of intact SIV genomes and persistence of ancestral variants.Cell Host Microbe2023
36739207Analyzing the unperturbed HIV-1 T cell reservoir.Trends Immunol2023
34781719A Possible Sterilizing Cure of HIV-1 Infection Without Stem Cell Transplantation.Ann Intern Med2022
35585080Therapeutic efficacy of an Ad26/MVA vaccine with SIV gp140 protein and vesatolimod in ART-suppressed rhesus macaques.NPJ Vaccines2022
35394875TCR-mimic bispecific antibodies to target the HIV-1 reservoir.Proc Natl Acad Sci U S A2022
36074794Measuring the latent reservoir for HIV-1: Quantification bias in near full-length genome sequencing methods.PLoS Pathog2022
36260688Genome-wide CRISPR screens identify combinations of candidate latency reversing agents for targeting the latent HIV-1 reservoir.Sci Transl Med2022
36345940The effect of induction immunosuppression for kidney transplant on the latent HIV reservoir.JCI Insight2022
35110411Complex decay dynamics of HIV virions, intact and defective proviruses, and 2LTR circles following initiation of antiretroviral therapy.Proc Natl Acad Sci U S A2022
34824401Engaging innate immunity in HIV-1 cure strategies.Nat Rev Immunol2022
34736342In Vivo Dynamics of the Latent Reservoir for HIV-1: New Insights and Implications for Cure.Annu Rev Pathol2022
33037877Nonstructured Treatment Interruptions Are Associated With Higher Human Immunodeficiency Virus Reservoir Size Measured by Intact Proviral DNA Assay in People Who Inject Drugs.J Infect Dis2021
33677480Impact of Anti-PD-1 and Anti-CTLA-4 on the Human Immunodeficiency Virus (HIV) Reservoir in People Living With HIV With Cancer on Antiretroviral Therapy: The AIDS Malignancy Consortium 095 Study.Clin Infect Dis2021
33674572Persistence of viral RNA in lymph nodes in ART-suppressed SIV/SHIV-infected Rhesus Macaques.Nat Commun2021
33586775Low Inducibility of Latent Human Immunodeficiency Virus Type 1 Proviruses as a Major Barrier to Cure.J Infect Dis2021
33361426Sequence Evaluation and Comparative Analysis of Novel Assays for Intact Proviral HIV-1 DNA.J Virol2021
33301425Antigen-driven clonal selection shapes the persistence of HIV-1-infected CD4+ T cells in vivo.J Clin Invest2021
33269401Similar Frequency and Inducibility of Intact Human Immunodeficiency Virus-1 Proviruses in Blood and Lymph Nodes.J Infect Dis2021
33441429Heightened resistance to host type 1 interferons characterizes HIV-1 at transmission and after antiretroviral therapy interruption.Sci Transl Med2021
32191639Longitudinal study reveals HIV-1-infected CD4+ T cell dynamics during long-term antiretroviral therapy.J Clin Invest2020
31996465Different human resting memory CD4<sup>+</sup> T cell subsets show similar low inducibility of latent HIV-1 proviruses.Sci Transl Med2020
32045386Differential decay of intact and defective proviral DNA in HIV-1-infected individuals on suppressive antiretroviral therapy.JCI Insight2020
33115867Shared Mechanisms Govern HIV Transcriptional Suppression in Circulating CD103[+] and Gut CD4[+] T Cells.J Virol2020
33087463Simian-Human Immunodeficiency Virus SHIV.C.CH505 Persistence in ART-Suppressed Infant Macaques Is Characterized by Elevated SHIV RNA in the Gut and a High Abundance of Intact SHIV DNA in Naive CD4<sup>+</sup> T Cells.J Virol2020
33239444Autologous IgG antibodies block outgrowth of a substantial but variable fraction of viruses in the latent reservoir for HIV-1.Proc Natl Acad Sci U S A2020
32690683Intact proviral DNA assay analysis of large cohorts of people with HIV provides a benchmark for the frequency and composition of persistent proviral DNA.Proc Natl Acad Sci U S A2020
32571938HSF1 inhibition attenuates HIV-1 latency reversal mediated by several candidate LRAs In Vitro and Ex Vivo.Proc Natl Acad Sci U S A2020
33016925Nonsuppressible HIV-1 viremia: a reflection of how the reservoir persists.J Clin Invest2020
32848246Distinct viral reservoirs in individuals with spontaneous control of HIV-1.Nature2020
32649866Allogeneic bone marrow transplantation with post-transplant cyclophosphamide for patients with HIV and haematological malignancies: a feasibility study.Lancet HIV2020
32987276Multiple genetic programs contribute to CD4 T cell memory differentiation and longevity by maintaining T cell quiescence.Cell Immunol2020
32895573Recommendations for measuring HIV reservoir size in cure-directed clinical trials.Nat Med2020
30700913A quantitative approach for measuring the reservoir of latent HIV-1 proviruses.Nature2019
31297681Incentives for Viral Suppression in People Living with HIV: A Randomized Clinical Trial.AIDS Behav2019
31295427The Landscape of Persistent Viral Genomes in ART-Treated SIV, SHIV, and HIV-2 Infections.Cell Host Microbe2019
29071475Assays to Measure Latency, Reservoirs, and Reactivation.Curr Top Microbiol Immunol2018
30129208Insight into treatment of HIV infection from viral dynamics models.Immunol Rev2018
29911997HIV-1 latent reservoir size and diversity are stable following brief treatment interruption.J Clin Invest2018
30232425The role of CD32 during HIV-1 infection.Nature2018
30083606CMPK2 and BCL-G are associated with type 1 interferon-induced HIV restriction in humans.Sci Adv2018
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Ragon Institute of MGH
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Co-authored papers 4
Alberto Bosque
George Washington University
Co-authored papers 4
Andrew E Rosenberg
Co-authored papers 4
Sharon R Lewin
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Michael P Busch
Vitalant Research Institute
Co-authored papers 3
Frederick M Hecht
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Daniel R Kuritzkes
Brigham and Women's Hospital, Harvard Medical School
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George M Shaw
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Denis Wirtz
Johns Hopkins University
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Chloe L Thio
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Eric Verdin
Buck Institute for Research on Aging
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Peter W Hunt
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Release 1.2