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Author Details

Matthew Wortham
Pediatric Diabetes Research Center, University of California
2007
20
12
Nathan Sheffield (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
37407581Beta cell dysfunction induced by bone morphogenetic protein (BMP)-2 is associated with histone modifications and decreased NeuroD1 chromatin binding.Cell Death Dis2023
34823065Deletion of ABCB10 in beta-cells protects from high-fat diet induced insulin resistance.Mol Metab2022
36162056Systemic LSD1 Inhibition Prevents Aberrant Remodeling of Metabolism in Obesity.Diabetes2022
35288669Sizing up beta cells made from stem cells.Nat Biotechnol2022
34030925Transcriptional mechanisms of pancreatic β-cell maturation and functional adaptation.Trends Endocrinol Metab2021
34467852Endoplasmic reticulum tubules limit the size of misfolded protein condensates.Elife2021
32350257LSD1-mediated enhancer silencing attenuates retinoic acid signalling during pancreatic endocrine cell development.Nat Commun2020
31362031Beta-cell dysfunction induced by non-cytotoxic concentrations of Interleukin-1β is associated with changes in expression of beta-cell maturity genes and associated histone modifications.Mol Cell Endocrinol2019
30517875Integrated In Vivo Quantitative Proteomics and Nutrient Tracing Reveals Age-Related Metabolic Rewiring of Pancreatic β Cell Function.Cell Rep2018
30398401Evaluation of Different Decellularization Protocols on the Generation of Pancreas-Derived Hydrogels.Tissue Eng Part C Methods2018
27166938High T Gives β Cells a Boost.Cell Metab2016
27615135Mechanisms of β-cell functional adaptation to changes in workload.Diabetes Obes Metab2016
25198066Chromatin accessibility mapping identifies mediators of basal transcription and retinoid-induced repression of OTX2 in medulloblastoma.PLoS One2014
22558385Aberrant Otx2 expression enhances migration and induces ectopic proliferation of hindbrain neuronal progenitor cells.PLoS One2012
23045699Global identification of MLL2-targeted loci reveals MLL2's role in diverse signaling pathways.Proc Natl Acad Sci U S A2012
22761590Extensive evolutionary changes in regulatory element activity during human origins are associated with altered gene expression and positive selection.PLoS Genet2012
22684456Apples to origins: identifying brain tumor stem cell genes by comparing transcriptomes of normal and cancer stem cells.Cancer Discov2012
20028867OTX2 is critical for the maintenance and progression of Shh-independent medulloblastomas.Cancer Res2010
18299981The transition from fatty liver to NASH associates with SAMe depletion in db/db mice fed a methionine choline-deficient diet.Dig Dis Sci2008
17576804Expression of constitutive androstane receptor, hepatic nuclear factor 4 alpha, and P450 oxidoreductase genes determines interindividual variability in basal expression and activity of a broad scope of xenobiotic metabolism genes in the human liver.Drug Metab Dispos2007
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Collaborators

Maike Sander
Co-authored papers 11
Hai Yan
Co-authored papers 5
Darell D Bigner
Co-authored papers 3
Yiping He
Co-authored papers 3
Bum-Kyu Lee
Cancer Research Center, University at Albany, State University of New York
Co-authored papers 2
Gregory E Crawford
Center for Genomic & Computational Biology, Duke University
Co-authored papers 2
Vishwanath R Iyer
Indian Institute of Technology Bombay
Co-authored papers 2
Terrence S Furey
University of North Carolina at Chapel Hill
Co-authored papers 2
Roger E McLendon
Co-authored papers 2
Lingyun Song
Center for Genomic & Computational Biology, Duke University
Co-authored papers 2
Stephen C J Parker
University of Michigan ann arbor
Co-authored papers 1
Allen Wang
Center for Epigenomics, University of California San Diego School of Medicine
Co-authored papers 1
Gregory A Wray
Duke University
Co-authored papers 1
Philip L S M Gordts
Co-authored papers 1
Kai Ge
Co-authored papers 1
Nickolas Papadopoulos
Co-authored papers 1
Gerald A Grant
Brigham and Women's Hospital, Harvard Medical School
Co-authored papers 1
Elliott H Margulies
National Human Genome Research Institute, National Institutes of Health
Co-authored papers 1
Kirk C Hansen
University of Colorado Anschutz Medical Campus
Co-authored papers 1
Martin R Larsen
University of Southern Denmark
Co-authored papers 1
Christopher Benner
Michigan State University College of Human Medicine
Co-authored papers 1
Yoichiro Shibata
Center for Genomic and Computational Biology, Duke University.
Co-authored papers 1
Michael G Rosenfeld
University of California San Diego
Co-authored papers 1
Paul A Northcott
St Jude Children's Research Hospital
Co-authored papers 1
Olivier Fedrigo
The Rockefeller University
Co-authored papers 1
John R Yates
TheScripps Research Institute
Co-authored papers 1
Michael D Taylor
The Hospital for Sick Children
Co-authored papers 1
Alok K Tewari
Dana-Farber Cancer Institute, Harvard Medical School
Co-authored papers 1
Jianxun Wang
986th Hospital of Air Force
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Darin London
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Release 1.2