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Author Details

Christoph Thiemermann
The William Harvey Research Institute, Queen Mary University of London
1984
473
83
PMIDPaper TitleJournal TitlePublished Year
35129479Inhibition of Bruton's Tyrosine Kinase Activity Attenuates Hemorrhagic Shock-Induced Multiple Organ Dysfunction in Rats.Ann Surg2023
35837955Inhibition of the JAK/STAT Pathway With Baricitinib Reduces the Multiple Organ Dysfunction Caused by Hemorrhagic Shock in Rats.Ann Surg2023
37249511Myocardial alterations following traumatic hemorrhagic injury.J Trauma Acute Care Surg2023
37108119The oDGal Mouse: A Novel, Physiologically Relevant Rodent Model of Sporadic Alzheimer's Disease.Int J Mol Sci2023
37470832Safety and efficacy of artesunate treatment in severely injured patients with traumatic hemorrhage. The TOP-ART randomized clinical trial.Intensive Care Med2023
37304276Editorial: Community series in translational insights into mechanisms and therapy of organ dysfunction in sepsis and trauma, volume II.Front Immunol2023
37068475Formyl Peptide Receptor Type 2 Deficiency in Myeloid Cells Amplifies Sepsis-Induced Cardiac Dysfunction.J Innate Immun2023
36911665Bruton's tyrosine kinase inhibition attenuates disease progression by reducing renal immune cell invasion in mice with hemolytic-uremic syndrome.Front Immunol2023
35178052Pharmacological Inhibition of FAK-Pyk2 Pathway Protects Against Organ Damage and Prolongs the Survival of Septic Mice.Front Immunol2022
35774785RG100204, A Novel Aquaporin-9 Inhibitor, Reduces Septic Cardiomyopathy and Multiple Organ Failure in Murine Sepsis.Front Immunol2022
35464452Inhibition of Macrophage Migration Inhibitory Factor Activity Attenuates Haemorrhagic Shock-Induced Multiple Organ Dysfunction in Rats.Front Immunol2022
36824160Advancements in nanomedicines for the detection and treatment of diabetic kidney disease.Biomater Biosyst2022
36142913The Potential Impact of Heparanase Activity and Endothelial Damage in COVID-19 Disease.J Clin Med2022
36119089ICOS-Fc as innovative immunomodulatory approach to counteract inflammation and organ injury in sepsis.Front Immunol2022
34939700Impact of metabolic disorders on the structural, functional, and immunological integrity of the blood-brain barrier: Therapeutic avenues.FASEB J2022
31188196Resolvin D1 Attenuates the Organ Injury Associated With Experimental Hemorrhagic Shock.Ann Surg2021
33505393Role of Metabolic Endotoxemia in Systemic Inflammation and Potential Interventions.Front Immunol2021
33801983Lipidomics Provides New Insight into Pathogenesis and Therapeutic Targets of the Ischemia-Reperfusion Injury.Int J Mol Sci2021
33608661Development and validation of a reinforcement learning algorithm to dynamically optimize mechanical ventilation in critical care.NPJ Digit Med2021
34349763A Synthetic Peptide Designed to Neutralize Lipopolysaccharides Attenuates Metaflammation and Diet-Induced Metabolic Derangements in Mice.Front Immunol2021
33370494Uninephrectomy and class II PI3K-C2β inactivation synergistically protect against obesity, insulin resistance and liver steatosis in mice.Am J Transplant2021
32413585Baricitinib counteracts metaflammation, thus protecting against diet-induced metabolic abnormalities in mice.Mol Metab2020
33659410Immunohistochemistry of Kidney a-SMA, Collagen 1, and Collagen 3, in A Novel Mouse Model of Reno-cardiac Syndrome.Bio Protoc2020
33163486Senescence and the Aging Immune System as Major Drivers of Chronic Kidney Disease.Front Cell Dev Biol2020
33162995X-Linked Immunodeficient Mice With No Functional Bruton's Tyrosine Kinase Are Protected From Sepsis-Induced Multiple Organ Failure.Front Immunol2020
33362805Corrigendum: Heparan Sulfate Induces Necroptosis in Murine Cardiomyocytes: A Medical-<i>in-Silico</i> Approach Combining <i>In Vitro</i> Experiments and Machine Learning.Front Immunol2020
33101267Editorial: Translational Insights Into Mechanisms and Therapy of Organ Dysfunction in Sepsis and Trauma.Front Immunol2020
32608058Inhibition of Bruton's TK regulates macrophage NF-κB and NLRP3 inflammasome activation in metabolic inflammation.Br J Pharmacol2020
32776354The hidden role of NLRP3 inflammasome in obesity-related COVID-19 exacerbations: Lessons for drug repurposing.Br J Pharmacol2020
32632751Vascular K<sub>ATP</sub> channels protect from cardiac dysfunction and preserve cardiac metabolism during endotoxemia.J Mol Med (Berl)2020
32670267The Effect of β<sub>2</sub>-Adrenoceptor Agonists on Leucocyte-Endothelial Adhesion in a Rodent Model of Laparotomy and Endotoxemia.Front Immunol2020
32983159RvE1 Attenuates Polymicrobial Sepsis-Induced Cardiac Dysfunction and Enhances Bacterial Clearance.Front Immunol2020
32213712Ribonuclease 1 attenuates septic cardiomyopathy and cardiac apoptosis in a murine model of polymicrobial sepsis.JCI Insight2020
30530834The MEK Inhibitor Trametinib Ameliorates Kidney Fibrosis by Suppressing ERK1/2 and mTORC1 Signaling.J Am Soc Nephrol2019
31866998Modeling Cardiac Dysfunction Following Traumatic Hemorrhage Injury: Impact on Myocardial Integrity.Front Immunol2019
30106874Part I: Minimum Quality Threshold in Preclinical Sepsis Studies (MQTiPSS) for Study Design and Humane Modeling Endpoints.Shock2019
30171861The Septic Heart: Current Understanding of Molecular Mechanisms and Clinical Implications.Chest2019
31552054Bruton's Tyrosine Kinase Inhibition Attenuates the Cardiac Dysfunction Caused by Cecal Ligation and Puncture in Mice.Front Immunol2019
31511159Response.Chest2019
31477171Batch effect exerts a bigger influence on the rat urinary metabolome and gut microbiota than uraemia: a cautionary tale.Microbiome2019
31114582Annexin-A1: Therapeutic Potential in Microvascular Disease.Front Immunol2019
30972066Identification of AnnexinA1 as an Endogenous Regulator of RhoA, and Its Role in the Pathophysiology and Experimental Therapy of Type-2 Diabetes.Front Immunol2019
30846068Response.Chest2019
30632166Neutrophil elastase plays a non-redundant role in remodeling the venular basement membrane and neutrophil diapedesis post-ischemia/reperfusion injury.J Pathol2019
30449337Retraction notice to "Enhanced IL-17 signalling following myocardial ischaemia/reperfusion injury" [Int. J. Cardiol. 163 (2013) 326-334].Int J Cardiol2019
30475325The Response to the Letter to the Editor Titled: "Is Triple Self-plagiarism "OK" If Only Made Transparent?" by Volker R Jacobs, MD, MBA.Shock2019
28817466Mitochondrial DNA in Acute Kidney Injury: Chicken or Egg?Shock2018
30106875Minimum Quality Threshold in Pre-Clinical Sepsis Studies (MQTiPSS): An International Expert Consensus Initiative for Improvement of Animal Modeling in Sepsis.Shock2018
29867926Scavenging Circulating Mitochondrial DNA as a Potential Therapeutic Option for Multiple Organ Dysfunction in Trauma Hemorrhage.Front Immunol2018
30105433Minimum Quality Threshold in Pre-Clinical Sepsis Studies (MQTiPSS): an international expert consensus initiative for improvement of animal modeling in sepsis.Infection2018
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Collaborators

University Hospital RWTH Aachen
Co-authored papers 20
Goethe University, University Hospital Frankfurt
Co-authored papers 17
University Hospital RWTH Aachen
Co-authored papers 9
Ludwig-Boltzmann Institute for Experimental and Clinical Traumatology
Co-authored papers 7
Emory University
Co-authored papers 5
University of Florida Health
Co-authored papers 5
St. Michael's Hospital
Co-authored papers 5
Ludwig Boltzmann Institute for Experimental and Clinical Traumatology
Co-authored papers 5
University of Florida College of Medicine.
Co-authored papers 5
Brown University
Co-authored papers 4
AUVA Trauma Hospital Salzburg
Co-authored papers 4
RWTH Aachen University
Co-authored papers 3
Trier University of Applied Sciences
Co-authored papers 3
University Hospital RWTH Aachen
Co-authored papers 3
RWTH Aachen University
Co-authored papers 3
William Harvey Research Institute, Queen Mary University of London
Co-authored papers 3
University of Konstanz
Co-authored papers 2
Joint Research Centre for Computational Biomedicine, University Hospital RWTH Aachen
Co-authored papers 1
Co-authored papers 1
University Hospital RWTH Aachen
Co-authored papers 1
Co-authored papers 1
University Hospital RWTH Aachen
Co-authored papers 1
William Harvey Research Institute, Queen Mary University of London
Co-authored papers 1
Co-authored papers 1
Trier University of Applied Sciences
Co-authored papers 1
University of Oxford
Co-authored papers 1
Erasme Hospital, Universite Libre de Bruxelles
Co-authored papers 1
Harvard T.H. Chan School of Public Health, MIT
Co-authored papers 1
Klinikum Der Ludwig-Maximilians-Universitat
Co-authored papers 1
Queen Mary Universityof London
Co-authored papers 1