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Author Details

Patrick J Grohar
Children's Hospital of Philadelphia.
2000
36
20
Nathan Sheffield (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36562272Importance of pharmacologic considerations in the development of targeted anticancer agents for children.Curr Opin Pediatr2023
37651654Long-Term Outcomes in Patients With Localized Ewing Sarcoma Treated With Interval-Compressed Chemotherapy on Children's Oncology Group Study AEWS0031.J Clin Oncol2023
36562272Importance of pharmacologic considerations in the development of targeted anticancer agents for children.Curr Opin Pediatr2023
37501549Children's Oncology Group's 2023 blueprint for research: Bone tumors.Pediatr Blood Cancer2023
37651654Long-Term Outcomes in Patients With Localized Ewing Sarcoma Treated With Interval-Compressed Chemotherapy on Children's Oncology Group Study AEWS0031.J Clin Oncol2023
37501549Children's Oncology Group's 2023 blueprint for research: Bone tumors.Pediatr Blood Cancer2023
36115869An international working group consensus report for the prioritization of molecular biomarkers for Ewing sarcoma.NPJ Precis Oncol2022
35657345Lurbinectedin Inhibits the EWS-WT1 Transcription Factor in Desmoplastic Small Round Cell Tumor.Mol Cancer Ther2022
35443099Ewing sarcoma and related FET family translocation-associated round cell tumors: A century of clinical and scientific progress.Genes Chromosomes Cancer2022
36115869An international working group consensus report for the prioritization of molecular biomarkers for Ewing sarcoma.NPJ Precis Oncol2022
35443099Ewing sarcoma and related FET family translocation-associated round cell tumors: A century of clinical and scientific progress.Genes Chromosomes Cancer2022
35657345Lurbinectedin Inhibits the EWS-WT1 Transcription Factor in Desmoplastic Small Round Cell Tumor.Mol Cancer Ther2022
33332735Mithramycin induces promoter reprogramming and differentiation of rhabdoid tumor.EMBO Mol Med2021
34137164Charting a path for prioritization of novel agents for clinical trials in osteosarcoma: A report from the Children's Oncology Group New Agents for Osteosarcoma Task Force.Pediatr Blood Cancer2021
33332735Mithramycin induces promoter reprogramming and differentiation of rhabdoid tumor.EMBO Mol Med2021
34976713One oncogene, several vulnerabilities: EWS/FLI targeted therapies for Ewing sarcoma.J Bone Oncol2021
34976713One oncogene, several vulnerabilities: EWS/FLI targeted therapies for Ewing sarcoma.J Bone Oncol2021
34137164Charting a path for prioritization of novel agents for clinical trials in osteosarcoma: A report from the Children's Oncology Group New Agents for Osteosarcoma Task Force.Pediatr Blood Cancer2021
32127464CDK9 Blockade Exploits Context-dependent Transcriptional Changes to Improve Activity and Limit Toxicity of Mithramycin for Ewing Sarcoma.Mol Cancer Ther2020
32127464CDK9 Blockade Exploits Context-dependent Transcriptional Changes to Improve Activity and Limit Toxicity of Mithramycin for Ewing Sarcoma.Mol Cancer Ther2020
32345977Desmoplastic small round cell tumor is dependent on the EWS-WT1 transcription factor.Oncogenesis2020
33488267Survey of Paediatric Oncologists and Pathologists regarding Their Views and Experiences with Variant Translocations in Ewing and Ewing-Like Sarcoma: A Report of the Children's Oncology Group.Sarcoma2020
33488267Survey of Paediatric Oncologists and Pathologists regarding Their Views and Experiences with Variant Translocations in Ewing and Ewing-Like Sarcoma: A Report of the Children's Oncology Group.Sarcoma2020
32345977Desmoplastic small round cell tumor is dependent on the EWS-WT1 transcription factor.Oncogenesis2020
30723142Trabectedin Inhibits EWS-FLI1 and Evicts SWI/SNF from Chromatin in a Schedule-dependent Manner.Clin Cancer Res2019
31031965Emerging novel agents for patients with advanced Ewing sarcoma: a report from the Children's Oncology Group (COG) New Agents for Ewing Sarcoma Task Force.F1000Res2019
31175181Severe Hepatotoxicity of Mithramycin Therapy Caused by Altered Expression of Hepatocellular Bile Transporters.Mol Pharmacol2019
30723142Trabectedin Inhibits EWS-FLI1 and Evicts SWI/SNF from Chromatin in a Schedule-dependent Manner.Clin Cancer Res2019
31175181Severe Hepatotoxicity of Mithramycin Therapy Caused by Altered Expression of Hepatocellular Bile Transporters.Mol Pharmacol2019
31031965Emerging novel agents for patients with advanced Ewing sarcoma: a report from the Children's Oncology Group (COG) New Agents for Ewing Sarcoma Task Force.F1000Res2019
28735378A phase I/II trial and pharmacokinetic study of mithramycin in children and adults with refractory Ewing sarcoma and EWS-FLI1 fusion transcript.Cancer Chemother Pharmacol2017
28735378A phase I/II trial and pharmacokinetic study of mithramycin in children and adults with refractory Ewing sarcoma and EWS-FLI1 fusion transcript.Cancer Chemother Pharmacol2017
28647886Wnt Signaling in Ewing Sarcoma, Osteosarcoma, and Malignant Peripheral Nerve Sheath Tumors.Curr Osteoporos Rep2017
28561686Advances in the Treatment of Pediatric Bone Sarcomas.Am Soc Clin Oncol Educ Book2017
28647886Wnt Signaling in Ewing Sarcoma, Osteosarcoma, and Malignant Peripheral Nerve Sheath Tumors.Curr Osteoporos Rep2017
28561686Advances in the Treatment of Pediatric Bone Sarcomas.Am Soc Clin Oncol Educ Book2017
26979396Identification of Mithramycin Analogues with Improved Targeting of the EWS-FLI1 Transcription Factor.Clin Cancer Res2016
26979396Identification of Mithramycin Analogues with Improved Targeting of the EWS-FLI1 Transcription Factor.Clin Cancer Res2016
26802024The second European interdisciplinary Ewing sarcoma research summit--A joint effort to deconstructing the multiple layers of a complex disease.Oncotarget2016
26961871Englerin A Inhibits EWS-FLI1 DNA Binding in Ewing Sarcoma Cells.J Biol Chem2016
26776507Functional Genomic Screening Reveals Splicing of the EWS-FLI1 Fusion Transcript as a Vulnerability in Ewing Sarcoma.Cell Rep2016
27697767Lurbinectedin Inactivates the Ewing Sarcoma Oncoprotein EWS-FLI1 by Redistributing It within the Nucleus.Cancer Res2016
27843394Trabectedin Followed by Irinotecan Can Stabilize Disease in Advanced Translocation-Positive Sarcomas with Acceptable Toxicity.Sarcoma2016
27671553<sup>18</sup>F-FLT Positron Emission Tomography (PET) is a Pharmacodynamic Marker for EWS-FLI1 Activity and Ewing Sarcoma.Sci Rep2016
27671553<sup>18</sup>F-FLT Positron Emission Tomography (PET) is a Pharmacodynamic Marker for EWS-FLI1 Activity and Ewing Sarcoma.Sci Rep2016
27697767Lurbinectedin Inactivates the Ewing Sarcoma Oncoprotein EWS-FLI1 by Redistributing It within the Nucleus.Cancer Res2016
27843394Trabectedin Followed by Irinotecan Can Stabilize Disease in Advanced Translocation-Positive Sarcomas with Acceptable Toxicity.Sarcoma2016
26776507Functional Genomic Screening Reveals Splicing of the EWS-FLI1 Fusion Transcript as a Vulnerability in Ewing Sarcoma.Cell Rep2016
26961871Englerin A Inhibits EWS-FLI1 DNA Binding in Ewing Sarcoma Cells.J Biol Chem2016
26802024The second European interdisciplinary Ewing sarcoma research summit--A joint effort to deconstructing the multiple layers of a complex disease.Oncotarget2016
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Collaborators

Lee J Helman
Osteosarcoma Institute
Co-authored papers 11
Stephen L Lessnick
The Ohio State University College of Medicine
Co-authored papers 7
Katherine A Janeway
Co-authored papers 7
Richard Gorlick
University of Texas MD Anderson Cancer Center
Co-authored papers 6
Steven G DuBois
Co-authored papers 4
Choh Yeung
Center for Cancer Research, National Cancer Institute
Co-authored papers 4
Chand Khanna
National Cancer Institute, National Institutes of Health
Co-authored papers 3
Elizabeth Stewart
St Jude Children's Research Hospital
Co-authored papers 3
Javed Khan
Center for Cancer Research, National Cancer Institute
Co-authored papers 3
Girma M Woldemichael
Center for Cancer Research, National Cancer Institute
Co-authored papers 3
Elizabeth R Lawlor
Seattle Children's Research Institute
Co-authored papers 3
Stefan Burdach
Technische Universitat Munchen
Co-authored papers 3
Peter J Houghton
The University of Texas Health Science Center at San Antonio
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Laurie B Griffin
University of Michigan ann arbor
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Uta Dirksen
University Hospital Essen, West German Cancer Center
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Arnulfo Mendoza
National Cancer Institute, National Institutes of Health
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Enrique de Alava
Servicio de Anatomia Patologica. Hospital Universitario Virgen del Rocio.
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Brigitte C Widemann
Co-authored papers 2
Jason T Yustein
Co-authored papers 2
Yves Pommier
Center for Cancer Research, National Cancer Institute
Co-authored papers 2
James B McMahon
Center for Cancer Research, National Cancer Institute
Co-authored papers 2
Jeffrey A Toretsky
Georgetown University Medical Center, Georgetown University
Co-authored papers 2
Thomas G P Gr??newald
German Cancer Research Center
Co-authored papers 2
Franck Tirode
Cancer Center of Lyon
Co-authored papers 2
Claudia Rossig
University Children's Hospital Muenster
Co-authored papers 2
Natasha J Caplen
Co-authored papers 2
Olivier Delattre
PSL Research University, Institut Curie Research Center, INSERM U, Institut Curie
Co-authored papers 2
Scott C Borinstein
Vanderbilt University Medical Center
Co-authored papers 2
Qing-Rong Chen
Center for Biomedical Informatics and Information Technology
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Release 1.2