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Author Details

Charles R Farber
University of Virginia
2003
98
32
Gloria M Sheynkman (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
37321985Genetic variation influences the skeletal response to hindlimb unloading in the eight founder strains of the diversity outbred mouse population.J Orthop Res2024
36379261Infertility and treatments used have minimal effects on first-trimester placental DNA methylation and gene expression.Fertil Steril2023
37962168Systems genetics approaches for understanding complex traits with relevance for human disease.Elife2023
37436066Single-Cell Transcriptomics of Bone Marrow Stromal Cells in Diversity Outbred Mice: A Model for Population-Level scRNA-Seq Studies.J Bone Miner Res2023
37333124Multi-Scale Cortical Bone Traits Vary in Two Mouse Models of Genetic Diversity.bioRxiv2023
36993769Long-read proteogenomics to connect disease-associated sQTLs to the protein isoform effectors of disease.bioRxiv2023
34710466Fentanyl-induced acute and conditioned behaviors in two inbred mouse lines: Potential role for Glyoxalase.Physiol Behav2022
35648061Genome-Wide mRNA Expression Analysis of Acute Psychological Stress Responses.MEDICC Rev2022
35695880Identification of Known and Novel Long Noncoding RNAs Potentially Responsible for the Effects of Bone Mineral Density (BMD) Genomewide Association Study (GWAS) Loci.J Bone Miner Res2022
36416764Transcriptome-wide association study and eQTL colocalization identify potentially causal genes responsible for human bone mineral density GWAS associations.Elife2022
35960994Bridging the splicing gap in human genetics with long-read RNA sequencing: finding the protein isoform drivers of disease.Hum Mol Genet2022
36028119Intramembranous bone regeneration in diversity outbred mice is heritable.Bone2022
33332990Exercise during pregnancy mitigates negative effects of parental obesity on metabolic function in adult mouse offspring.J Appl Physiol (1985)2021
33792563Genomic variants within chromosome 14q32.32 regulate bone mass through MARK3 signaling in osteoblasts.J Clin Invest2021
33900658Osteoblasts Generate Testosterone From DHEA and Activate Androgen Signaling in Prostate Cancer Cells.J Bone Miner Res2021
35008699MicroRNA-30b Is Both Necessary and Sufficient for Interleukin-21 Receptor-Mediated Angiogenesis in Experimental Peripheral Arterial Disease.Int J Mol Sci2021
34761080Genetic variability affects the skeletal response to immobilization in founder strains of the diversity outbred mouse population.Bone Rep2021
34467232A computational approach for identification of core modules from a co-expression network and GWAS data.STAR Protoc2021
34465678Genetic variability affects the response of skeletal muscle to disuse.J Musculoskelet Neuronal Interact2021
34630861Current evidence on potential of adipose derived stem cells to enhance bone regeneration and future projection.World J Stem Cells2021
34099702Systems genetics in diversity outbred mice inform BMD GWAS and identify determinants of bone strength.Nat Commun2021
34125409Using "-omics" Data to Inform Genome-wide Association Studies (GWASs) in the Osteoporosis Field.Curr Osteoporos Rep2021
32375599RNA-sequencing analysis of differential gene expression associated with arterial stiffness.Vascular2020
32937138Identification of a Core Module for Bone Mineral Density through the Integration of a Co-expression Network and GWAS Data.Cell Rep2020
32619458Acute psychological stress, autonomic function, and arterial stiffness among women.Int J Psychophysiol2020
32311160Old Mice Have Less Transcriptional Activation But Similar Periosteal Cell Proliferation Compared to Young-Adult Mice in Response to in vivo Mechanical Loading.J Bone Miner Res2020
32304342A novel voluntary weightlifting model in mice promotes muscle adaptation and insulin sensitivity with simultaneous enhancement of autophagy and mTOR pathway.FASEB J2020
32497039Genetic analysis of osteoblast activity identifies Zbtb40 as a regulator of osteoblast activity and bone mass.PLoS Genet2020
30611556Differential gene expression during placentation in pregnancies conceived with different fertility treatments compared with spontaneous pregnancies.Fertil Steril2019
31844829Genetic Dissection of Femoral and Tibial Microarchitecture.JBMR Plus2019
31434789The RNA demethylase FTO is required for maintenance of bone mass and functions to protect osteoblasts from genotoxic damage.Proc Natl Acad Sci U S A2019
31042701Mouse genome-wide association and systems genetics identifies Lhfp as a regulator of bone mass.PLoS Genet2019
30888730Meta-Analysis of Genomewide Association Studies Reveals Genetic Variants for Hip Bone Geometry.J Bone Miner Res2019
30551918Single limb immobilization model for bone loss from unloading.J Biomech2019
30445606Differences in First-Trimester Maternal Metabolomic Profiles in Pregnancies Conceived From Fertility Treatments.J Clin Endocrinol Metab2019
30586702Antiangiogenic VEGF<sub>165</sub>b Regulates Macrophage Polarization via S100A8/S100A9 in Peripheral Artery Disease.Circulation2019
30470485Dissecting the Genetics of Osteoporosis using Systems Approaches.Trends Genet2019
29335024Sex differences in the late first trimester human placenta transcriptome.Biol Sex Differ2018
27837649Using GWAS to identify novel therapeutic targets for osteoporosis.Transl Res2017
28082324Genetic Dissection of a QTL Affecting Bone Geometry.G3 (Bethesda)2017
28356443A MicroRNA93-Interferon Regulatory Factor-9-Immunoresponsive Gene-1-Itaconic Acid Pathway Modulates M2-Like Macrophage Polarization to Revascularize Ischemic Muscle.Circulation2017
28125793The State of Systems Genetics in 2017.Cell Syst2017
27866947Integrating GWAS and Co-expression Network Data Identifies Bone Mineral Density Genes SPTBN1 and MARK3 and an Osteoblast Functional Module.Cell Syst2017
27099397The Hybrid Mouse Diversity Panel: a resource for systems genetics analyses of metabolic and cardiovascular traits.J Lipid Res2016
27718505Optimization of techniques for multiple platform testing in small, precious samples such as human chorionic villus sampling.Prenat Diagn2016
27378017Network Analysis Implicates Alpha-Synuclein (Snca) in the Regulation of Ovariectomy-Induced Bone Loss.Sci Rep2016
27126736RhoA determines lineage fate of mesenchymal stem cells by modulating CTGF-VEGF complex in extracellular matrix.Nat Commun2016
26845690Genomic Modifiers of Natural Killer Cells, Immune Responsiveness and Lymphoid Tissue Remodeling Together Increase Host Resistance to Viral Infection.PLoS Pathog2016
25613955Overlapping mouse subcongenic strains successfully separate two linked body fat QTL on distal MMU 2.BMC Genomics2015
26367794Whole-genome sequencing identifies EN1 as a determinant of bone density and fracture.Nature2015
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Collaborators

Aldons J Lusis
Co-authored papers 22
Larry D Mesner
Center for Public Health Genomics, University of Virginia
Co-authored papers 13
Eleazar Eskin
Co-authored papers 9
Stephen S Rich
Co-authored papers 7
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Maine Medical Center Research Institute
Co-authored papers 7
Thomas A Drake
Co-authored papers 6
Hyun Min Kang
Co-authored papers 6
Daniel Pomp
Co-authored papers 5
Jerome I Rotter
Co-authored papers 5
Yii-Der Ida Chen
Co-authored papers 5
Eric E Schadt
Icahn School of Medicine at Mount Sinai
Co-authored papers 5
Mark O Goodarzi
Co-authored papers 5
Ricardo A Verdugo
Co-authored papers 4
Suna Onengut-Gumuscu
Co-authored papers 4
Lu Lu
University of Tennessee Health Science Center
Co-authored papers 4
Robert W Williams
Mayo Clinic
Co-authored papers 4
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Co-authored papers 4
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University Medical Center Rotterdam
Co-authored papers 3
Karol Estrada
Brandeis University
Co-authored papers 3
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Erasmus University Medical Center
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David Geffen School of Medicine, University of California los angeles
Co-authored papers 3
Gary A Churchill
Tufts University
Co-authored papers 3
David Karasik
Co-authored papers 3
Maria Carola Zillikens
Co-authored papers 3
Matteo Pellegrini
Co-authored papers 3
John Brent Richards
Lady Davis Institute for Medical Research, Jewish General Hospital
Co-authored papers 3
Douglas P Kiel
Hinda and Arthur Marcus Institute for Aging Research
Co-authored papers 3
Stephen D Turner
Co-authored papers 3
Tim D Spector
King's College London
Co-authored papers 3
Abraham A Palmer
McMaster University & St. Joseph's Healthcare Hamilton
Co-authored papers 2
Release 1.2