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Author Details

John Aach
Harvard Medical School
2000
45
35
Prashant Mali (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36258039How collaboration between bioethicists and neuroscientists can advance research.Nat Neurosci2022
33462496Characterizing the portability of phage-encoded homologous recombination proteins.Nat Chem Biol2021
33693773Barcoded oligonucleotides ligated on RNA amplified for multiplexed and parallel in situ analyses.Nucleic Acids Res2021
33288905Chromosome-scale, haplotype-resolved assembly of human genomes.Nat Biotechnol2021
31860070A haplotype-aware de novo assembly of related individuals using pedigree sequence graph.Bioinformatics2020
28545477Optimizing complex phenotypes through model-guided multiplex genome engineering.Genome Biol2017
28494857Correction: Addressing the ethical issues raised by synthetic human entities with embryo-like features.Elife2017
28494856Addressing the ethical issues raised by synthetic human entities with embryo-like features.Elife2017
28991237Corrigendum: Engineering and optimising deaminase fusions for genome editing.Nat Commun2017
27804970Engineering and optimising deaminase fusions for genome editing.Nat Commun2016
25414332Multi-kilobase homozygous targeted gene replacement in human induced pluripotent stem cells.Nucleic Acids Res2015
26456528Genome-wide inactivation of porcine endogenous retroviruses (PERVs).Science2015
25675209Fluorescent in situ sequencing (FISSEQ) of RNA for gene expression profiling in intact cells and tissues.Nat Protoc2015
25730490Highly efficient Cas9-mediated transcriptional programming.Nat Methods2015
24452804Rational optimization of tolC as a powerful dual selectable marker for genome engineering.Nucleic Acids Res2014
25425480Targeted and genome-wide sequencing reveal single nucleotide variations impacting specificity of Cas9 in human stem cells.Nat Commun2014
25252978Multiplex single-molecule interaction profiling of DNA-barcoded proteins.Nature2014
25180701Improved cell-free RNA and protein synthesis system.PLoS One2014
24578530Highly multiplexed subcellular RNA sequencing in situ.Science2014
23287722RNA-guided human genome engineering via Cas9.Science2013
23907390Optimization of scarless human stem cell genome editing.Nucleic Acids Res2013
23907171CAS9 transcriptional activators for target specificity screening and paired nickases for cooperative genome engineering.Nat Biotechnol2013
23929339Multiplex and homologous recombination-mediated genome editing in Arabidopsis and Nicotiana benthamiana using guide RNA and Cas9.Nat Biotechnol2013
24028704On the design of clone-based haplotyping.Genome Biol2013
23460208Genome engineering in Saccharomyces cerevisiae using CRISPR-Cas systems.Nucleic Acids Res2013
23503053Barcoding cells using cell-surface programmable DNA-binding domains.Nat Methods2013
22797899A public resource facilitating clinical use of genomes.Proc Natl Acad Sci U S A2012
21245846Proteome-wide systems analysis of a cellulosic biofuel-producing microbe.Mol Syst Biol2011
20373666Personal genomes in progress: from the human genome project to the personal genome project.Dialogues Clin Neurosci2010
19478186Genome-wide identification of human RNA editing sites by parallel DNA capturing and sequencing.Science2009
19620972Digital RNA allelotyping reveals tissue-specific and allele-specific gene expression in human.Nat Methods2009
19525355Multiplex padlock targeted sequencing reveals human hypermutable CpG variations.Genome Res2009
18260140Identification of molecular markers of bipolar cells in the murine retina.J Comp Neurol2008
17588932Quantitative morphological signatures define local signaling networks regulating cell morphology.Science2007
16493423Long-range polony haplotyping of individual human chromosome molecules.Nat Genet2006
17016519Global gene expression of Prochlorococcus ecotypes in response to changes in nitrogen availability.Mol Syst Biol2006
15938023Accommodation or prediction?Science2005
15064081Mathematical models of diffusion-constrained polymerase chain reactions: basis of high-throughput nucleic acid assays and simple self-organizing systems.J Theor Biol2004
12769849Computational and experimental identification of C. elegans microRNAs.Mol Cell2003
12032321Measuring absolute expression with microarrays with a calibrated reference sample and an extended signal intensity range.Proc Natl Acad Sci U S A2002
12413400Automated modelling of signal transduction networks.BMC Bioinformatics2002
11395426Aligning gene expression time series with time warping algorithms.Bioinformatics2001
11237010Computational comparison of two draft sequences of the human genome.Nature2001
11726920Minimum information about a microarray experiment (MIAME)-toward standards for microarray data.Nat Genet2001
10779484Systematic management and analysis of yeast gene expression data.Genome Res2000
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Collaborators

Harvard Medical School
Co-authored papers 41
University of California San Diego
Co-authored papers 9
College of Resources and Environment, Southwest University
Co-authored papers 8
China Pharmaceutical University
Co-authored papers 7
Department of Food and Nutrition, Kongju National University
Co-authored papers 6
Wyss Institute for Biologically Inspired Engineering, Harvard University
Co-authored papers 5
Universitat Pompeu Fabra
Co-authored papers 5
Beth Israel Deaconess Medical Center and Harvard Medical School
Co-authored papers 4
Co-authored papers 4
Texas Children's Hospital, Baylor College of Medicine
Co-authored papers 4
University of California San Francisco
Co-authored papers 4
Royal College of Surgeons in Ireland
Co-authored papers 3
Harvard Medical School
Co-authored papers 3
Co-authored papers 3
University of Tennessee Health Science Center
Co-authored papers 3
Harvard University
Co-authored papers 3
Co-authored papers 3
Johns Hopkins University
Co-authored papers 3
Wyss Institute for Biologically Inspired Engineering, Harvard University
Co-authored papers 3
Harvard Medical School
Co-authored papers 3
Massachusetts Institute of Technology, USA Broad Institute
Co-authored papers 2
Co-authored papers 2
Renaissance Computing Institute, University of North Carolina at Chapel Hill
Co-authored papers 2
Co-authored papers 2
inc. 2424 Erwin Road
Co-authored papers 2
Genome Institute of Singapore
Co-authored papers 2
Wyss Institute for Biologically Inspired Engineering, Harvard University
Co-authored papers 2
Broad Institute of MIT and Harvard
Co-authored papers 2
Brigham and Women's Hospital (Y.K.
Co-authored papers 2
Harvard Medical School
Co-authored papers 2