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Author Details

Ankur Chakravarthy
Princess Margaret Cancer Centre, University Health Network
2013
28
21
PMIDPaper TitleJournal TitlePublished Year
37726227Ratio of stemness to interferon signalling as a biomarker and therapeutic target of myeloproliferative neoplasm progression to acute myeloid leukaemia.Br J Haematol2024
36455236Cerebrospinal fluid methylome-based liquid biopsies for accurate malignant brain neoplasm classification.Neuro Oncol2023
37600767The chromatin and single-cell transcriptional landscapes of CD4 T cells in inflammatory bowel disease link risk loci with a proinflammatory Th17 cell population.Front Immunol2023
34614192DNA methylation-based prognostic subtypes of chordoma tumors in tissue and plasma.Neuro Oncol2022
35584120H3K9 methylation drives resistance to androgen receptor-antagonist therapy in prostate cancer.Proc Natl Acad Sci U S A2022
34433969A clinically applicable integrative molecular classification of meningiomas.Nature2021
33654322Publisher Correction: Epigenetic therapy induces transcription of inverted SINEs and ADAR1 dependency.Nature2021
33609448DNA hypomethylating agents increase activation and cytolytic activity of CD8<sup>+</sup> T cells.Mol Cell2021
32178828Using epigenetic data to estimate immune composition in admixed samples.Methods Enzymol2020
33087935Epigenetic therapy induces transcription of inverted SINEs and ADAR1 dependency.Nature2020
32572265Detection and discrimination of intracranial tumors using plasma cell-free DNA methylomes.Nat Med2020
32753546An open-label, phase II multicohort study of an oral hypomethylating agent CC-486 and durvalumab in advanced solid tumors.J Immunother Cancer2020
32122909NOX4 Inhibition Potentiates Immunotherapy by Overcoming Cancer-Associated Fibroblast-Mediated CD8 T-cell Exclusion from Tumors.Cancer Res2020
30723290Epigenetic therapy in immune-oncology.Nat Rev Cancer2019
29760532Apoptotic cell-induced AhR activity is required for immunological tolerance and suppression of systemic lupus erythematosus in mice and humans.Nat Immunol2018
30104673Pan-cancer deconvolution of tumour composition using DNA methylation.Nat Commun2018
29937226LSD1 Ablation Stimulates Anti-tumor Immunity and Enables Checkpoint Blockade.Cell2018
30098776Frequent HPV-independent p16/INK4A overexpression in head and neck cancer.Oral Oncol2018
30429608Sensitive tumour detection and classification using plasma cell-free DNA methylomes.Nature2018
30389940Author Correction: Pan-cancer deconvolution of tumour composition using DNA methylation.Nat Commun2018
30410077TGF-β-associated extracellular matrix genes link cancer-associated fibroblasts to immune evasion and immunotherapy failure.Nat Commun2018
28212753The TRAIL-Induced Cancer Secretome Promotes a Tumor-Supportive Immune Microenvironment via CCR2.Mol Cell2017
27325650CSN1 Somatic Mutations in Penile Squamous Cell Carcinoma.Cancer Res2016
27863190Human Papillomavirus Drives Tumor Development Throughout the Head and Neck: Improved Prognosis Is Associated With an Immune Response Largely Restricted to the Oropharynx.J Clin Oncol2016
24336642ChAMP: 450k Chip Analysis Methylation Pipeline.Bioinformatics2014
27308321When defense turns into attack: Antiviral cytidine deaminases linked to somatic mutagenesis in HPV-associated cancer.Mol Cell Oncol2014
24910434APOBEC-mediated cytosine deamination links PIK3CA helical domain mutations to human papillomavirus-driven tumor development.Cell Rep2014
23419152Identification and functional validation of HPV-mediated hypermethylation in head and neck squamous cell carcinoma.Genome Med2013
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Collaborators

Daniel D De Carvalho
Princess Margaret Cancer Centre, University Health Network
Co-authored papers 13
Helen Loo Yau
Princess Margaret Cancer Centre, University Health Network
Co-authored papers 6
Charles A Ishak
Princess Margaret Cancer Centre, University Health Network
Co-authored papers 4
Vikas Patil
Princess Margaret Hospital
Co-authored papers 4
Gelareh Zadeh
University of Toronto
Co-authored papers 4
Tiago da Silva Medina
International Research Center, A.C.Camargo Cancer Center
Co-authored papers 4
Farshad Nassiri
Toronto Western Hospital, University Health Network, University of Toronto
Co-authored papers 4
Kenneth Aldape
National Cancer Institute
Co-authored papers 3
Stephan Beck
UCL Cancer Institute, University College London
Co-authored papers 3
Andrew E Teschendorff
UCL Cancer Institute, University College London
Co-authored papers 2
Trevor J Pugh
Princess Margaret Cancer Centre, University Health Network
Co-authored papers 2
Olivia Singh
Princess Margaret Cancer Centre
Co-authored papers 2
Rajat Singhania
Virginia Polytechnic Institute and State University
Co-authored papers 2
Shirin Karimi
Princess Margaret Cancer Centre
Co-authored papers 2
Thomas Kislinger
Princess Margaret Cancer Centre, University Health Network, University of Toronto
Co-authored papers 2
Jeff Liu
Princess Margaret Cancer Centre, University Health Network and University of Toronto
Co-authored papers 2
Philippe L Bedard
Princess Margaret Cancer Centre, University Health Network
Co-authored papers 2
Dianne Chadwick
University Health Network
Co-authored papers 1
Andrew Macklin
Margaret Cancer Center
Co-authored papers 1
Lillian L Siu
Princess Margaret Cancer Centre, University Ave
Co-authored papers 1
Qingxia Wei
Princess Margaret Cancer Centre, University Health Network and University of Toronto
Co-authored papers 1
Joan E Wither
Schroeder Arthritis Institute, Krembil Research Institute, University Health Network
Co-authored papers 1
Zhuo Chen
The First Hospital of Lanzhou University
Co-authored papers 1
William A Faubion
Mayo Clinic
Co-authored papers 1
David Neil Hayes
Center for Cancer Research, University of Tennessee Health Science Center
Co-authored papers 1
Zahi Touma
Schroeder Arthritis Institute, Krembil Research Institute, University Health Network
Co-authored papers 1
Rosario I Corona
Cedars-Sinai Medical Center
Co-authored papers 1
Lydia Y Liu
University of Toronto
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Shahbaz Khan
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