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Author Details

Alain Laederach
University of North Carolina at Chapel Hill
1972
85
33
Timothy Clark (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36792358Structural analysis of MALAT1 long noncoding RNA in cells and in evolution.RNA2023
37546801Orb2 enables rare-codon-enriched mRNA expression during <i>Drosophila</i> neuron differentiation.bioRxiv2023
37647143Coordinated expression of replication-dependent histone genes from multiple loci promotes histone homeostasis in <i>Drosophila</i>.Mol Biol Cell2023
34741198Disease-associated human genetic variation through the lens of precursor and mature RNA structure.Hum Genet2022
35380695Sequence and tissue targeting specificity of ZFP36L2 reveals Elavl2 as a novel target with co-regulation potential.Nucleic Acids Res2022
35695373Quantitative prediction of variant effects on alternative splicing in <i>MAPT</i> using endogenous pre-messenger RNA structure probing.Elife2022
35522036Distinct responses to rare codons in select <i>Drosophila</i> tissues.Elife2022
36107773Global 5'-UTR RNA structure regulates translation of a SERPINA1 mRNA.Nucleic Acids Res2022
34896370A novel algorithm for ranking RNA structure candidates.Biophys J2022
34283611To Knot or Not to Knot: Multiple Conformations of the SARS-CoV-2 Frameshifting RNA Element.J Am Chem Soc2021
33821274To knot or not to knot: Multiple conformations of the SARS-CoV-2 frameshifting RNA element.bioRxiv2021
34850114In vivo architecture of the telomerase RNA catalytic core in Trypanosoma brucei.Nucleic Acids Res2021
34905538Identifying proximal RNA interactions from cDNA-encoded crosslinks with ShapeJumper.PLoS Comput Biol2021
34763026Cigarette smoking-associated isoform switching and 3' UTR lengthening via alternative polyadenylation.Genomics2021
34784346Alternative poly-adenylation modulates α1-antitrypsin expression in chronic obstructive pulmonary disease.PLoS Genet2021
34121404Direct Mapping of Higher-Order RNA Interactions by SHAPE-JuMP.Biochemistry2021
32999019Using SHAPE-MaP To Model RNA Secondary Structure and Identify 3'UTR Variation in Chikungunya Virus.J Virol2020
33173926Characterization of a COPD-Associated <i>NPNT</i> Functional Splicing Genetic Variant in Human Lung Tissue via Long-Read Sequencing.medRxiv2020
31332385The structure of the influenza A virus genome.Nat Microbiol2019
34113790Towards an understanding of RNA structural modalities: a riboswitch case study.Comput Math Biophys2019
29317542Allele-specific SHAPE-MaP assessment of the effects of somatic variation and protein binding on mRNA structure.RNA2018
30150364A Functional riboSNitch in the 3' Untranslated Region of <i>FKBP5</i> Alters MicroRNA-320a Binding Efficiency and Mediates Vulnerability to Chronic Post-Traumatic Pain.J Neurosci2018
30137633A pipeline for computational design of novel RNA-like topologies.Nucleic Acids Res2018
29894169Messenger RNA Structure Regulates Translation Initiation: A Mechanism Exploited from Bacteria to Humans.Biochemistry2018
29361131Structural divergence creates new functional features in alphavirus genomes.Nucleic Acids Res2018
27396578Transcending the prediction paradigm: novel applications of SHAPE to RNA function and evolution.Wiley Interdiscip Rev RNA2017
28455422Impact of RNA structure on ZFP36L2 interaction with luteinizing hormone receptor mRNA.RNA2017
28130241Classification of RNA structure change by 'gazing' at experimental data.Bioinformatics2017
28445416Structure-Function Model for Kissing Loop Interactions That Initiate Dimerization of Ty1 RNA.Viruses2017
29109288An RNA structure-mediated, posttranscriptional model of human α-1-antitrypsin expression.Proc Natl Acad Sci U S A2017
28625696Comparative Visualization of the RNA Suboptimal Conformational Ensemble In Vivo.Biophys J2017
27067391A unified analytic framework for prioritization of non-coding variants of uncertain significance in heritable breast and ovarian cancer.BMC Med Genomics2016
27642846Selecting against accidental RNA interactions.Elife2016
27381913Primary and Secondary Sequence Structure Requirements for Recognition and Discrimination of Target RNAs by Pseudomonas aeruginosa RsmA and RsmF.J Bacteriol2016
25618847Detecting riboSNitches with RNA folding algorithms: a genome-wide benchmark.Nucleic Acids Res2015
26575236RNA folding: A clear path to RNA catalysis.Nat Chem Biol2015
26414013Single Molecule Cluster Analysis dissects splicing pathway conformational dynamics.Nat Methods2015
26480348Increased Transcript Complexity in Genes Associated with Chronic Obstructive Pulmonary Disease.PLoS One2015
26115028The potential of the riboSNitch in personalized medicine.Wiley Interdiscip Rev RNA2015
25999316Multiple conformations are a conserved and regulatory feature of the RB1 5' UTR.RNA2015
24009312Small RNAs derived from lncRNA RNase MRP have gene-silencing activity relevant to human cartilage-hair hypoplasia.Hum Mol Genet2014
24586236Mapping the kinetic barriers of a Large RNA molecule's folding landscape.PLoS One2014
24476882Molecular biology: A second layer of information in RNA.Nature2014
23528092Understanding the role of three-dimensional topology in determining the folding intermediates of group I introns.Biophys J2013
23935473Evolutionary evidence for alternative structure in RNA sequence co-variation.PLoS Comput Biol2013
22109839Structural effects of linkage disequilibrium on the transcriptome.RNA2012
22759654Evaluating our ability to predict the structural disruption of RNA by SNPs.BMC Genomics2012
22281772Toward interoperable bioscience data.Nat Genet2012
21210530Membrane RNAs in bacteria.Mol Microbiol2011
21917492A novel application of pattern recognition for accurate SNP and indel discovery from high-throughput data: targeted resequencing of the glucocorticoid receptor co-chaperone FKBP5 in a Caucasian population.Mol Genet Metab2011
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Collaborators

Russ B Altman
Stanford University
Co-authored papers 9
Michael Brenowitz
Albert Einstein College of Medicine
Co-authored papers 8
Rhiju Das
Stanford University School of Medicine
Co-authored papers 6
Craig P Hersh
Co-authored papers 3
Peter J Castaldi
Harvard Medical School
Co-authored papers 3
Evonne McArthur
Co-authored papers 2
Nikolay V Dokholyan
Pennsylvania State University College of Medicine
Co-authored papers 2
Michael H Cho
Brigham and Women's Hospital Channing Division of Network Medicine
Co-authored papers 2
Amanda Birmingham
Center for Computational Biology & Bioinformatics , University of California
Co-authored papers 2
Neocles B Leontis
Bowling Green State University
Co-authored papers 2
Edwin K Silverman
Brigham and Women's Hospital
Co-authored papers 2
Kenneth S Plante
University of Texas Medical Branch
Co-authored papers 2
Clayton R Morrison
University of North Carolina School of Medicine
Co-authored papers 2
Rob Knight
University of California
Co-authored papers 2
Philippe Rocca-Serra
University of Oxford
Co-authored papers 2
Mark T Heise
University of North Carolina at Chapel Hill.
Co-authored papers 2
Jack A Gilbert
Scripps Institution of Oceanography, University of California San Diego
Co-authored papers 2
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Leibniz Institute for Plant Biochemistry
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Lee Harland
Connected Discovery Ltd
Co-authored papers 1
Aabida Saferali
Co-authored papers 1
Magali Roux
Institut des epileptiques
Co-authored papers 1
Oliver Hofmann
University of Melbourne
Co-authored papers 1
Joel S Parker
Lineberger Cancer Center, University of North Carolina
Co-authored papers 1
Hong Fang
National Center for Toxicological Research (NCTR)
Co-authored papers 1
Christoph Steinbeck
Institute for Inorganic and Analytical Chemistry, Friedrich Schiller University Jena
Co-authored papers 1
David Baker
University of Washington
Co-authored papers 1
Julian L Griffin
Cambridge University
Co-authored papers 1
Linda A Amaral-Zettler
NIOZ Royal Netherlands Institute for Sea Research
Co-authored papers 1
Sarah D Linnstaedt
Institute for Trauma Recovery, University of North Carolina at Chapel Hill
Co-authored papers 1
Nikos C Kyrpides
Co-authored papers 1
Release 1.2