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Author Details

Brandon J Wainwright
The University of Queensland Diamantina Institute, The University of Queensland
1985
174
51
Antoine Forget (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36757207Efficient detection and monitoring of pediatric brain malignancies with liquid biopsy based on patient-specific somatic mutation screening.Neuro Oncol2023
37333134Preventing recurrence in Sonic Hedgehog Subgroup Medulloblastoma using the OLIG2 inhibitor CT-179.Res Sq2023
37127652Spatial transcriptomic analysis of Sonic hedgehog medulloblastoma identifies that the loss of heterogeneity and promotion of differentiation underlies the response to CDK4/6 inhibition.Genome Med2023
36448458Elongator and the role of its subcomplexes in human diseases.EMBO Mol Med2023
36864284A novel ELP1 mutation impairs the function of the Elongator complex and causes a severe neurodevelopmental phenotype.J Hum Genet2023
35698786Functional divergence of the two Elongator subcomplexes during neurodevelopment.EMBO Mol Med2022
33258962Patient-derived orthotopic xenograft models of medulloblastoma lack a functional blood-brain barrier.Neuro Oncol2021
33656514Vincristine-induced peripheral neuropathy is driven by canonical NLRP3 activation and IL-1β release.J Exp Med2021
33549134Genetic and functional interaction network analysis reveals global enrichment of regulatory T cell genes influencing basal cell carcinoma susceptibility.Genome Med2021
34154646Systems pharmacogenomics identifies novel targets and clinically actionable therapeutics for medulloblastoma.Genome Med2021
33976153Elp2 mutations perturb the epitranscriptome and lead to a complex neurodevelopmental phenotype.Nat Commun2021
34330843SOX9 Defines Distinct Populations of Cells in SHH Medulloblastoma but Is Not Required for Math1-Driven Tumor Formation.Mol Cancer Res2021
34254999Tumor cells generate astrocyte-like cells that contribute to SHH-driven medulloblastoma relapse.J Exp Med2021
32296180Germline Elongator mutations in Sonic Hedgehog medulloblastoma.Nature2020
31838646Common Regulatory Targets of NFIA, NFIX and NFIB during Postnatal Cerebellar Development.Cerebellum2020
32970781Correction: Proliferation of Murine Midbrain Neural Stem Cells Depends upon an Endogenous Sonic Hedgehog (Shh) Source.PLoS One2020
32444239Ectopic expression of SOX18 in Basal cell carcinoma negatively regulates tumour progression.J Dermatol Sci2020
30511336Granule neuron precursor cell proliferation is regulated by NFIX and intersectin 1 during postnatal cerebellar development.Brain Struct Funct2019
30657775Identification of CD24 as a marker of Patched1 deleted medulloblastoma-initiating neural progenitor cells.PLoS One2019
29109083Activated Hedgehog-GLI Signaling Causes Congenital Ureteropelvic Junction Obstruction.J Am Soc Nephrol2018
30097576Elongator mutation in mice induces neurodegeneration and ataxia-like behavior.Nat Commun2018
27498049Patched Receptors Sense, Interpret, and Establish an Epidermal Hedgehog Signaling Gradient.J Invest Dermatol2017
28939119Patched1 patterns Fibroblast growth factor 10 and Forkhead box F1 expression during pulmonary branch formation.Mech Dev2017
29137400Downregulation of the Sonic Hedgehog/Gli pathway transcriptional target Neogenin-1 is associated with basal cell carcinoma aggressiveness.Oncotarget2017
28650469A compartmentalized phosphoinositide signaling axis at cilia is regulated by INPP5E to maintain cilia and promote Sonic Hedgehog medulloblastoma.Oncogene2017
28512199Dominant-negative <i>Sox18</i> function inhibits dermal papilla maturation and differentiation in all murine hair types.Development2017
28637687Inhibition of CDK4/6 by Palbociclib Significantly Extends Survival in Medulloblastoma Patient-Derived Xenograft Mouse Models.Clin Cancer Res2017
27878595Cell-type-specific expression of NFIX in the developing and adult cerebellum.Brain Struct Funct2017
26773048MicroRNA Biogenesis and Hedgehog-Patched Signaling Cooperate to Regulate an Important Developmental Transition in Granule Cell Development.Genetics2016
27847465The Many Faces of Elongator in Neurodevelopment and Disease.Front Mol Neurosci2016
25156673Nuclear factor one transcription factors: Divergent functions in developmental versus adult stem cell populations.Dev Dyn2015
25910616MicroRNAs Promote Granule Cell Expansion in the Cerebellum Through Gli2.Cerebellum2015
23775842Neogenin1 is a Sonic Hedgehog target in medulloblastoma and is necessary for cell cycle progression.Int J Cancer2014
25164012Zfx facilitates tumorigenesis caused by activation of the Hedgehog pathway.Cancer Res2014
24492243Patched 1 and patched 2 redundancy has a key role in regulating epidermal differentiation.J Invest Dermatol2014
24264598Medulloblastoma Down Under 2013: a report from the third annual meeting of the International Medulloblastoma Working Group.Acta Neuropathol2014
22907436Direct effects of Bmi1 on p53 protein stability inactivates oncoprotein stress responses in embryonal cancer precursor cells at tumor initiation.Oncogene2013
24167280Sleeping Beauty mutagenesis in a mouse medulloblastoma model defines networks that discriminate between human molecular subgroups.Proc Natl Acad Sci U S A2013
23900075Patched1 is required in neural crest cells for the prevention of orofacial clefts.Hum Mol Genet2013
23776550Proliferation of murine midbrain neural stem cells depends upon an endogenous sonic hedgehog (Shh) source.PLoS One2013
23404854Murine basal cell carcinoma leads to tumor-mediated alterations in endocrine Igf1 signaling.Endocr Relat Cancer2013
22228095Mutations in mouse Ift144 model the craniofacial, limb and rib defects in skeletal ciliopathies.Hum Mol Genet2012
23034632Kif7 regulates Gli2 through Sufu-dependent and -independent functions during skin development and tumorigenesis.Development2012
22550175Hedgehog pathway inhibitor saridegib (IPI-926) increases lifespan in a mouse medulloblastoma model.Proc Natl Acad Sci U S A2012
20969845Ptch1-mediated dosage-dependent action of Shh signaling regulates neural progenitor development at late gestational stages.Dev Biol2011
21841314Hedgehog/Notch-induced premature gliogenesis represents a new disease mechanism for Hirschsprung disease in mice and humans.J Clin Invest2011
21718593Tumor shrinkage by cyclopamine tartrate through inhibiting hedgehog signaling.Chin J Cancer2011
21379383Sonic hedgehog and notch signaling can cooperate to regulate neurogenic divisions of neocortical progenitors.PLoS One2011
20018874Wnt2 regulates progenitor proliferation in the developing ventral midbrain.J Biol Chem2010
20682855An antibody against the colony-stimulating factor 1 receptor depletes the resident subset of monocytes and tissue- and tumor-associated macrophages but does not inhibit inflammation.Blood2010
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Collaborators

Robert Williamson
Murdoch Children's Research Institute
Co-authored papers 24
Martin Farrall
Co-authored papers 19
Georgia Chenevix-Trench
QIMR Berghofer Medical Research Institute
Co-authored papers 16
Marija Kojic
The University of Queensland Diamantina Institute, The University of Queensland
Co-authored papers 12
David A Hume
Mater Research Institute-UQ, Translational Research Institute
Co-authored papers 11
Xavier Estivill
Sidra Medical Center
Co-authored papers 9
Michael D Taylor
The Hospital for Sick Children
Co-authored papers 8
Melissa J Davis
Co-authored papers 7
Marc Remke
and Clinical Immunology, Heinrich Heine University, University Hospital Dusseldorf
Co-authored papers 6
Michael Dean
National Cancer Institute
Co-authored papers 5
James M Olson
Clinical Research Division, Fred Hutchinson Cancer Center
Co-authored papers 4
Torsten Pietsch
Co-authored papers 4
Stefan M Pfister
Hopp Children's Cancer Center Heidelberg (KiTZ)
Co-authored papers 4
Marcel Kool
Hopp Children's Cancer Center (KiTZ)
Co-authored papers 4
Mark F Leppert
University of Utah
Co-authored papers 3
Nicholas G Gottardo
Perth Children's Hospital
Co-authored papers 3
Arthur L Beaudet
Baylor College of Medicine
Co-authored papers 3
Sean M Grimmond
The University of Melbourne
Co-authored papers 3
Alistair R R Forrest
RIKEN Center for Integrative Medical Sciences
Co-authored papers 3
James T Rutka
Hospital for Sick Children
Co-authored papers 2
Christine A Wells
The University of Melbourne
Co-authored papers 2
Bryan W Day
Co-authored papers 2
Yusuke Nakamura
Japanese Foundation for Cancer Research
Co-authored papers 2
Stefan Rutkowski
University Medical Center Hamburg-Eppendorf
Co-authored papers 2
Juha Kere
Folkhalsan Research Center, University of Helsinki
Co-authored papers 2
David T W Jones
Hopp Children's Cancer Center Heidelberg (KiTZ)
Co-authored papers 2
Juliet D French
QIMR Berghofer Medical Research Institute
Co-authored papers 2
Amar Gajjar
St. Jude Children's Research Hospital
Co-authored papers 2
Andrey Korshunov
Institute of Pathology, University Hospital Heidelberg
Co-authored papers 2
Giles W Robinson
St. Jude Children's Research Hospital
Co-authored papers 2
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