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Author Details

Mahmoud A Bassal
Cancer Science Institute of Singapore, National University of Singapore
2015
26
12
Jake Y. Chen (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36609400Targeted systematic evolution of an RNA platform neutralizing DNMT1 function and controlling DNA methylation.Nat Commun2023
37461690SALL4B, not targeted by IMiD, is important for SALL4-mediated tumorigenesis.bioRxiv2023
37371524The Interplay between Dysregulated Metabolism and Epigenetics in Cancer.Biomolecules2023
36609400Targeted systematic evolution of an RNA platform neutralizing DNMT1 function and controlling DNA methylation.Nat Commun2023
37371524The Interplay between Dysregulated Metabolism and Epigenetics in Cancer.Biomolecules2023
37461690SALL4B, not targeted by IMiD, is important for SALL4-mediated tumorigenesis.bioRxiv2023
34965583ChIP-AP: an integrated analysis pipeline for unbiased ChIP-seq analysis.Brief Bioinform2022
35840577Author Correction: Germline mutations in mitochondrial complex I reveal genetic and targetable vulnerability in IDH1-mutant acute myeloid leukaemia.Nat Commun2022
36269860Long noncoding RNA-mediated activation of PROTOR1/PRR5-AKT signaling shunt downstream of PI3K in triple-negative breast cancer.Proc Natl Acad Sci U S A2022
35613022Demethylation and Up-Regulation of an Oncogene after Hypomethylating Therapy.N Engl J Med2022
35551192Germline mutations in mitochondrial complex I reveal genetic and targetable vulnerability in IDH1-mutant acute myeloid leukaemia.Nat Commun2022
36115580Ex Vivo Expansion of Phenotypic and Transcriptomic Chronic Myeloid Leukemia Stem Cells.Exp Hematol2022
35033660Intravitreal gene therapy restores the autophagy-lysosomal pathway and attenuates retinal degeneration in cathepsin D-deficient mice.Neurobiol Dis2022
34965583ChIP-AP: an integrated analysis pipeline for unbiased ChIP-seq analysis.Brief Bioinform2022
35551192Germline mutations in mitochondrial complex I reveal genetic and targetable vulnerability in IDH1-mutant acute myeloid leukaemia.Nat Commun2022
35613022Demethylation and Up-Regulation of an Oncogene after Hypomethylating Therapy.N Engl J Med2022
35840577Author Correction: Germline mutations in mitochondrial complex I reveal genetic and targetable vulnerability in IDH1-mutant acute myeloid leukaemia.Nat Commun2022
36269860Long noncoding RNA-mediated activation of PROTOR1/PRR5-AKT signaling shunt downstream of PI3K in triple-negative breast cancer.Proc Natl Acad Sci U S A2022
36115580Ex Vivo Expansion of Phenotypic and Transcriptomic Chronic Myeloid Leukemia Stem Cells.Exp Hematol2022
35033660Intravitreal gene therapy restores the autophagy-lysosomal pathway and attenuates retinal degeneration in cathepsin D-deficient mice.Neurobiol Dis2022
33030566[Experimental therapeutic approaches for the treatment of retinal dystrophy in neuronal ceroid lipofuscinosis].Ophthalmologe2021
34078745Cis P-tau underlies vascular contribution to cognitive impairment and dementia and can be effectively targeted by immunotherapy in mice.Sci Transl Med2021
33971010Myeloid lncRNA LOUP mediates opposing regulatory effects of RUNX1 and RUNX1-ETO in t(8;21) AML.Blood2021
33547048E-cadherin is regulated by GATA-2 and marks the early commitment of mouse hematopoietic progenitors to the basophil and mast cell fates.Sci Immunol2021
34120146Metabolic alterations mediated by STAT3 promotes drug persistence in CML.Leukemia2021
33854168Identification of a targetable KRAS-mutant epithelial population in non-small cell lung cancer.Commun Biol2021
33800998Rapid and Progressive Loss of Multiple Retinal Cell Types in Cathepsin D-Deficient Mice-An Animal Model of CLN10 Disease.Cells2021
33030566[Experimental therapeutic approaches for the treatment of retinal dystrophy in neuronal ceroid lipofuscinosis].Ophthalmologe2021
33406418Zinc Finger Protein SALL4 Functions through an AT-Rich Motif to Regulate Gene Expression.Cell Rep2021
34458869A modified CUT&RUN protocol and analysis pipeline to identify transcription factor binding sites in human cell lines.STAR Protoc2021
34597139Pseudogene-mediated DNA demethylation leads to oncogene activation.Sci Adv2021
33854168Identification of a targetable KRAS-mutant epithelial population in non-small cell lung cancer.Commun Biol2021
33547048E-cadherin is regulated by GATA-2 and marks the early commitment of mouse hematopoietic progenitors to the basophil and mast cell fates.Sci Immunol2021
33800998Rapid and Progressive Loss of Multiple Retinal Cell Types in Cathepsin D-Deficient Mice-An Animal Model of CLN10 Disease.Cells2021
34458869A modified CUT&RUN protocol and analysis pipeline to identify transcription factor binding sites in human cell lines.STAR Protoc2021
34597139Pseudogene-mediated DNA demethylation leads to oncogene activation.Sci Adv2021
34078745Cis P-tau underlies vascular contribution to cognitive impairment and dementia and can be effectively targeted by immunotherapy in mice.Sci Transl Med2021
34120146Metabolic alterations mediated by STAT3 promotes drug persistence in CML.Leukemia2021
33971010Myeloid lncRNA LOUP mediates opposing regulatory effects of RUNX1 and RUNX1-ETO in t(8;21) AML.Blood2021
33406418Zinc Finger Protein SALL4 Functions through an AT-Rich Motif to Regulate Gene Expression.Cell Rep2021
31282275Enzyme replacement therapy with recombinant pro-CTSD (cathepsin D) corrects defective proteolysis and autophagy in neuronal ceroid lipofuscinosis.Autophagy2020
32932933Intravitreal Co-Administration of GDNF and CNTF Confers Synergistic and Long-Lasting Protection against Injury-Induced Cell Death of Retinal Ganglion Cells in Mice.Cells2020
32966797Scavenging of Labile Heme by Hemopexin Is a Key Checkpoint in Cancer Growth and Metastases.Cell Rep2020
31282275Enzyme replacement therapy with recombinant pro-CTSD (cathepsin D) corrects defective proteolysis and autophagy in neuronal ceroid lipofuscinosis.Autophagy2020
32966797Scavenging of Labile Heme by Hemopexin Is a Key Checkpoint in Cancer Growth and Metastases.Cell Rep2020
32932933Intravitreal Co-Administration of GDNF and CNTF Confers Synergistic and Long-Lasting Protection against Injury-Induced Cell Death of Retinal Ganglion Cells in Mice.Cells2020
31446059New High-Throughput Screening Identifies Compounds That Reduce Viability Specifically in Liver Cancer Cells That Express High Levels of SALL4 by Inhibiting Oxidative Phosphorylation.Gastroenterology2019
31446059New High-Throughput Screening Identifies Compounds That Reduce Viability Specifically in Liver Cancer Cells That Express High Levels of SALL4 by Inhibiting Oxidative Phosphorylation.Gastroenterology2019
29891941Rare variants in Fanconi anemia genes are enriched in acute myeloid leukemia.Blood Cancer J2018
29891941Rare variants in Fanconi anemia genes are enriched in acute myeloid leukemia.Blood Cancer J2018
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Collaborators

Daniel G Tenen
Harvard Stem Cell Institute, Harvard Medical School
Co-authored papers 16
Robert S Welner
University of Alabama at Birmingham
Co-authored papers 4
Henry Yang
Cancer Science Institute of Singapore, National University of Singapore
Co-authored papers 3
Sweta B Patel
The University of Alabama at Birmingham School of Medicine
Co-authored papers 3
Anna L Brown
Adelaide Medical School, University of Adelaide
Co-authored papers 3
Ravindra Majeti
Stanford University School of Medicine
Co-authored papers 2
Valeriya Kuznetsova
University of Alabama at Birmingham
Co-authored papers 2
Davide Stefanoni
Vita-Salute San Raffaele University
Co-authored papers 1
Marla Weetall
Co-authored papers 1
Marzia Del Re
University of Pisa
Co-authored papers 1
Raphael Bueno
Co-authored papers 1
Virginia Camacho
Boston Children's Hospital, Harvard Medical School
Co-authored papers 1
Rui Lu
O'Neal Comprehensive Cancer Center, University of Alabama at Birmingham
Co-authored papers 1
Victoria R Matkins
O'Neal Comprehensive Cancer Center, University of Alabama at Birmingham
Co-authored papers 1
Huck-Hui Ng
Co-authored papers 1
Matthew A Brown
Co-authored papers 1
Zongliang Yue
University of Alabama at Birmingham, USA Informatics Institute
Co-authored papers 1
Jun Qi
Dana-Farber Cancer Institute
Co-authored papers 1
Ashley T Hoang
O'Neal Comprehensive Cancer Center, University of Alabama at Birmingham
Co-authored papers 1
Li Ying
Cancer Institute of Singapore, National University of Singapore
Co-authored papers 1
Brittany L Crown
O'Neal Comprehensive Cancer Center, University of Alabama at Birmingham
Co-authored papers 1
Jake Y Chen
Co-authored papers 1
Ravi Bhatia
University of Alabama at Birmingham
Co-authored papers 1
Victor M Darley-Usmar
University of Alabama at Birmingham
Co-authored papers 1
Jake Y. Chen (CM4AI)
University of Alabama at Birmingham
Co-authored papers 1
Travis Nemkov
University of Colorado Anschutz Medical Campus
Co-authored papers 1
Samuel L Wolock
Beth Israel Deaconess Medical Center
Co-authored papers 1
Gloria A Benavides
University of Alabama at Birmingham
Co-authored papers 1
Anders Bjartell
Skane University Hospital, Lund University
Co-authored papers 1
Markus Glatzel
Co-authored papers 1
Release 1.2