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Author Details

Isabel Sola
Campus Universidad Autonoma de Madrid
1995
88
35
Kirsten Obernier (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36602354Atypical Mutational Spectrum of SARS-CoV-2 Replicating in the Presence of Ribavirin.Antimicrob Agents Chemother2023
37623322SARS-CoV-2 ORF8 accessory protein is a virulence factor.mBio2023
37947413Correction for Castaño-Rodriguez et al., "Role of Severe Acute Respiratory Syndrome Coronavirus Viroporins E, 3a, and 8a in Replication and Pathogenesis".mBio2023
37942479Cell type dependent stability and virulence of a recombinant SARS-CoV-2, and engineering of a propagation deficient RNA replicon to analyze virus RNA synthesis.Front Cell Infect Microbiol2023
37097842ICTV Virus Taxonomy Profile: <i>Coronaviridae</i> 2023.J Gen Virol2023
37197199Contribution to pathogenesis of accessory proteins of deadly human coronaviruses.Front Cell Infect Microbiol2023
36625656SARS-CoV-2-Mediated Lung Edema and Replication Are Diminished by Cystic Fibrosis Transmembrane Conductance Regulator Modulators.mBio2023
36854765Engineering potent live attenuated coronavirus vaccines by targeted inactivation of the immune evasive viral deubiquitinase.Nat Commun2023
35323099Suitability of transiently expressed antibodies for clinical studies: product quality consistency at different production scales.MAbs2022
35471062An ACE2-blocking antibody confers broad neutralization and protection against Omicron and other SARS-CoV-2 variants of concern.Sci Immunol2022
35966177Nature of viruses and pandemics: Coronaviruses.Curr Res Immunol2022
36360660Pulsed-Xenon Ultraviolet Light Highly Inactivates Human Coronaviruses on Solid Surfaces, Particularly SARS-CoV-2.Int J Environ Res Public Health2022
36129908MERS-CoV ORF4b is a virulence factor involved in the inflammatory pathology induced in the lungs of mice.PLoS Pathog2022
35012962Preclinical and randomized phase I studies of plitidepsin in adults hospitalized with COVID-19.Life Sci Alliance2022
35314834Eicosanoid signalling blockade protects middle-aged mice from severe COVID-19.Nature2022
34851142Development of a Single-Cycle Infectious SARS-CoV-2 Virus Replicon Particle System for Use in Biosafety Level 2 Laboratories.J Virol2022
35229638Contribution of Host miRNA-223-3p to SARS-CoV-Induced Lung Inflammatory Pathology.mBio2022
33144319Middle East Respiratory Syndrome Coronavirus Gene 5 Modulates Pathogenesis in Mice.J Virol2021
33653888Genetically Engineered Live-Attenuated Middle East Respiratory Syndrome Coronavirus Viruses Confer Full Protection against Lethal Infection.mBio2021
33731724A conserved immunogenic and vulnerable site on the coronavirus spike protein delineated by cross-reactive monoclonal antibodies.Nat Commun2021
34517762MOV10 Helicase Interacts with Coronavirus Nucleocapsid Protein and Has Antiviral Activity.mBio2021
34686605Middle East respiratory syndrome coronavirus vaccine based on a propagation-defective RNA replicon elicited sterilizing immunity in mice.Proc Natl Acad Sci U S A2021
34075384Plitidepsin has a positive therapeutic index in adult patients with COVID-19 requiring hospitalization.medRxiv2021
34014525Viral PDZ Binding Motifs Influence Cell Behavior Through the Interaction with Cellular Proteins Containing PDZ Domains.Methods Mol Biol2021
32900263Cross-neutralization activity against SARS-CoV-2 is present in currently available intravenous immunoglobulins.Immunotherapy2020
32635598Canonical and Noncanonical Autophagy as Potential Targets for COVID-19.Cells2020
31349683Recombinant Chimeric Transmissible Gastroenteritis Virus (TGEV) - Porcine Epidemic Diarrhea Virus (PEDV) Virus Provides Protection against Virulent PEDV.Viruses2019
31861369Minimum Determinants of Transmissible Gastroenteritis Virus Enteric Tropism Are Located in the N-Terminus of Spike Protein.Pathogens2019
29370303MERS-CoV 4b protein interferes with the NF-κB-dependent innate immune response during infection.PLoS Pathog2018
30101189Chimeric camel/human heavy-chain antibodies protect against MERS-CoV infection.Sci Adv2018
30110630Adaptive Evolution of MERS-CoV to Species Variation in DPP4.Cell Rep2018
29789363Role of Severe Acute Respiratory Syndrome Coronavirus Viroporins E, 3a, and 8a in Replication and Pathogenesis.mBio2018
28931424Erratum to: Role of transcription regulatory sequence in regulation of gene expression and replication of porcine reproductive and respiratory syndrome virus.Vet Res2017
28216251SARS-CoV-Encoded Small RNAs Contribute to Infection-Associated Lung Pathology.Cell Host Microbe2017
28797297Role of transcription regulatory sequence in regulation of gene expression and replication of porcine reproductive and respiratory syndrome virus.Vet Res2017
27009949Mutagenesis of Coronavirus nsp14 Reveals Its Potential Role in Modulation of the Innate Immune Response.J Virol2016
27783669Middle East Respiratory Coronavirus Accessory Protein 4a Inhibits PKR-Mediated Antiviral Stress Responses.PLoS Pathog2016
27712626Molecular Basis of Coronavirus Virulence and Vaccine Development.Adv Virus Res2016
27397100Virulence factors in porcine coronaviruses and vaccine design.Virus Res2016
26025418Virus Research. Foreword. Nidoviruses II.Virus Res2015
26958916Continuous and Discontinuous RNA Synthesis in Coronaviruses.Annu Rev Virol2015
24930446Coronavirus reverse genetic systems: infectious clones and replicons.Virus Res2014
25483881Virus Research. Nidoviruses I. Foreword.Virus Res2014
25261606Reprint of: Coronavirus reverse genetic systems: infectious clones and replicons.Virus Res2014
25108114Antigenic structures stably expressed by recombinant TGEV-derived vectors.Virology2014
23055566Long-distance RNA-RNA interactions in the coronavirus genome form high-order structures promoting discontinuous RNA synthesis during transcription.J Virol2013
23824792Alphacoronavirus protein 7 modulates host innate immune response.J Virol2013
24023385Engineering a replication-competent, propagation-defective Middle East respiratory syndrome coronavirus as a vaccine candidate.mBio2013
23966403Transmissible gastroenteritis coronavirus genome packaging signal is located at the 5' end of the genome and promotes viral RNA incorporation into virions in a replication-independent process.J Virol2013
21411518The polypyrimidine tract-binding protein affects coronavirus RNA accumulation levels and relocalizes viral RNAs to novel cytoplasmic domains different from replication-transcription sites.J Virol2011
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Collaborators

Campus Universidad Autonoma de Madrid
Co-authored papers 86
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Co-authored papers 40
Erasmus Medical Center
Co-authored papers 5
The University of Texas MD Anderson Cancer Center
Co-authored papers 3
Icahn School of Medicine at Mount Sinai
Co-authored papers 3
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Co-authored papers 2
Hospital Universitario HM Monteprincipe, HM Hospitales
Co-authored papers 2
University College London
Co-authored papers 2
University of the Basque Country UPV/EHU
Co-authored papers 2
Departamento de Toxicologia y Farmacologia Preclinica
Co-authored papers 2
Clinical Development
Co-authored papers 2
University of California San Francisco
Co-authored papers 2
IrsiCaixa AIDS Research Institute, Hospital Universitari Germans Trias i Pujol
Co-authored papers 2
Hospital Universitario HM Monteprincipe, HM Hospitales
Co-authored papers 2
Clinical Development
Co-authored papers 2
University of Geneva
Co-authored papers 2
Instituto de Salud Carlos III, Hospital Universitario La Princesa
Co-authored papers 2
Hospital Germans Trias i Pujol
Co-authored papers 2
Hospital Universitario Quironsalud Madrid
Co-authored papers 2
Clinical R&D
Co-authored papers 2
IrsiCaixa AIDS Research Institute, Hospital Universitari Germans Trias i Pujol
Co-authored papers 2
Hospital Universitario de Getafe
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University College London
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University of California San Francisco
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Universidad Europea
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Hospital Universitario de La Princesa
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Hospital Universitario de Getafe
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Quantitative Biosciences Institute (QBI) Coronavirus Research Group (QCRG)
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Hospital Universitario Ramon y Cajal
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