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Author Details

Brett D Lindenbach
Yale University School of Medicine
1993
85
42
Wade Schulz (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36697369Positive-strand RNA viruses-a Keystone Symposia report.Ann N Y Acad Sci2023
37668367Astrovirus replication is dependent on induction of double-membrane vesicles through a PI3K-dependent, LC3-independent pathway.J Virol2023
37090568Astrovirus replication is dependent on induction of double membrane vesicles through a PI3K-dependent, LC3-independent pathway.bioRxiv2023
35301314De novo emergence of a remdesivir resistance mutation during treatment of persistent SARS-CoV-2 infection in an immunocompromised patient: a case report.Nat Commun2022
35353000The <i>In Vivo</i> and <i>In Vitro</i> Architecture of the Hepatitis C Virus RNA Genome Uncovers Functional RNA Secondary and Tertiary Structures.J Virol2022
35840179Reinventing positive-strand RNA virus reverse genetics.Adv Virus Res2022
33147444Genome-wide CRISPR Screens Reveal Host Factors Critical for SARS-CoV-2 Infection.Cell2021
33786375Potent Noncovalent Inhibitors of the Main Protease of SARS-CoV-2 from Molecular Sculpting of the Drug Perampanel Guided by Free Energy Perturbation Calculations.ACS Cent Sci2021
34909781<i>De novo</i> emergence of a remdesivir resistance mutation during treatment of persistent SARS-CoV-2 infection in an immunocompromised patient: A case report.medRxiv2021
34408808Optimization of Triarylpyridinone Inhibitors of the Main Protease of SARS-CoV-2 to Low-Nanomolar Antiviral Potency.ACS Med Chem Lett2021
34405956Placenta-derived interferon-stimulated gene 20 controls ZIKA virus infection.EMBO Rep2021
34185680Restriction of SARS-CoV-2 replication by targeting programmed -1 ribosomal frameshifting.Proc Natl Acad Sci U S A2021
32291299A Sensitive Yellow Fever Virus Entry Reporter Identifies Valosin-Containing Protein (VCP/p97) as an Essential Host Factor for Flavivirus Uncoating.mBio2020
33106809Restriction of SARS-CoV-2 Replication by Targeting Programmed -1 Ribosomal Frameshifting In Vitro.bioRxiv2020
32869025Genome-wide CRISPR screen reveals host genes that regulate SARS-CoV-2 infection.bioRxiv2020
32641492Hepatitis C virus NS3-4A protease regulates the lipid environment for RNA replication by cleaving host enzyme 24-dehydrocholesterol reductase.J Biol Chem2020
30759391MARCH8 Ubiquitinates the Hepatitis C Virus Nonstructural 2 Protein and Mediates Viral Envelopment.Cell Rep2019
31591191Screening <i>Legionella</i> effectors for antiviral effects reveals Rab1 GTPase as a proviral factor coopted for tombusvirus replication.Proc Natl Acad Sci U S A2019
29317514Erratum for Barouch-Bentov et al., "Hepatitis C Virus Proteins Interact with the Endosomal Sorting Complex Required for Transport (ESCRT) Machinery via Ubiquitination To Facilitate Viral Envelopment".mBio2018
29535204Interactions between the Hepatitis C Virus Nonstructural 2 Protein and Host Adaptor Proteins 1 and 4 Orchestrate Virus Release.mBio2018
29477639Critical challenges and emerging opportunities in hepatitis C virus research in an era of potent antiviral therapy: Considerations for scientists and funding agencies.Virus Res2018
28968665Recovery of Infectious Hepatitis C Virus From Injection Paraphernalia: Implications for Prevention Programs Serving People Who Inject Drugs.J Infect Dis2018
28588082IRE1α promotes viral infection by conferring resistance to apoptosis.Sci Signal2017
29253880The amino-terminus of the hepatitis C virus (HCV) p7 viroporin and its cleavage from glycoprotein E2-p7 precursor determine specific infectivity and secretion levels of HCV particle types.PLoS Pathog2017
26924328The Coding Region of the HCV Genome Contains a Network of Regulatory RNA Structures.Mol Cell2016
27706161Full Genome Sequence and sfRNA Interferon Antagonist Activity of Zika Virus from Recife, Brazil.PLoS Negl Trop Dis2016
27613665HSV-2 enhances ZIKV infection of the placenta and induces apoptosis in first-trimester trophoblast cells.Am J Reprod Immunol2016
27803188Hepatitis C Virus Proteins Interact with the Endosomal Sorting Complex Required for Transport (ESCRT) Machinery via Ubiquitination To Facilitate Viral Envelopment.mBio2016
27595140Zika virus productively infects primary human placenta-specific macrophages.JCI Insight2016
27565347Vaginal Exposure to Zika Virus during Pregnancy Leads to Fetal Brain Infection.Cell2016
27568284Zika Virus Disrupts Phospho-TBK1 Localization and Mitosis in Human Neuroepithelial Stem Cells and Radial Glia.Cell Rep2016
26745726Correction: A Conserved NS3 Surface Patch Orchestrates NS2 Protease Stimulation, NS5A Hyperphosphorylation and HCV Genome Replication.PLoS Pathog2016
26853717What's next for hepatitis C virus research?Hepatology2016
25774920A conserved NS3 surface patch orchestrates NS2 protease stimulation, NS5A hyperphosphorylation and HCV genome replication.PLoS Pathog2015
26536599Survival of Hepatitis C Virus in Syringes Is Dependent on the Design of the Syringe-Needle and Dead Space Volume.PLoS One2015
26700029Correction: Survival of Hepatitis C Virus in Syringes Is Dependent on the Design of the Syringe-Needle and Dead Space Volume.PLoS One2015
26034767Disinfection of syringes contaminated with hepatitis C virus by rinsing with household products.Open Forum Infect Dis2015
25875808Hepatitis C virus RNA replication depends on specific cis- and trans-acting activities of viral nonstructural proteins.PLoS Pathog2015
24173222Hepatitis C virus RNA replication and virus particle assembly require specific dimerization of the NS4A protein transmembrane domain.J Virol2014
25031324Expanding the proteome of an RNA virus by phosphorylation of an intrinsically disordered viral protein.J Biol Chem2014
24965468The linker region of NS3 plays a critical role in the replication and infectivity of hepatitis C virus.J Virol2014
24752411Genome-wide analysis of host factors in nodavirus RNA replication.PLoS One2014
24273176Hepatitis C virus maintains infectivity for weeks after drying on inanimate surfaces at room temperature: implications for risks of transmission.J Infect Dis2014
23463202Virion assembly and release.Curr Top Microbiol Immunol2013
24018384The ins and outs of hepatitis C virus entry and assembly.Nat Rev Microbiol2013
22185796A summary of the 18th International Symposium on Hepatitis C Virus and Related Viruses.Gastroenterology2012
21238940Understanding how hepatitis C virus builds its unctuous home.Cell Host Microbe2011
22028650Trafficking of hepatitis C virus core protein during virus particle assembly.PLoS Pathog2011
22000018Structural insights into RNA recognition by RIG-I.Cell2011
21147927Hepatitis C virus NS2 coordinates virus particle assembly through physical interactions with the E1-E2 glycoprotein and NS3-NS4A enzyme complexes.J Virol2011
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Collaborators

Charles M Rice
Rockefeller University
Co-authored papers 22
Anna Marie Pyle
Yale University, USA Howard Hughes Medical Institute
Co-authored papers 10
Craig B Wilen
Yale School of Medicine
Co-authored papers 5
Akiko Iwasaki
Yale University
Co-authored papers 4
Shirit Einav
Stanford University School of Medicine
Co-authored papers 4
Chris Sander
Broad Institute of MIT and Harvard
Co-authored papers 2
Elsio A Wunder
Yale School of Public Health
Co-authored papers 2
David van Dijk
Yale School of Medicine, Yale University
Co-authored papers 2
Mihaela Zavolan
Co-authored papers 2
Pavitra Roychoudhury
Fred Hutchinson Cancer Center
Co-authored papers 2
Wade Schulz (CM4AI)
Yale University
Co-authored papers 2
Donna M Tscherne
Mount Sinai School of Medicine
Co-authored papers 2
Alexander L Greninger
University of Washington Medical Center
Co-authored papers 2
Onyema Ogbuagu
Yale School of Medicine, Yale University
Co-authored papers 2
Albert I Ko
Instituto Goncalo Moniz, Yale School of Public Health
Co-authored papers 2
Peiwen Lu
Yale University School of Medicine
Co-authored papers 2
John G Doench
Co-authored papers 2
Michael Gale
Center for Innate Immunity and Immune Disease, University of Washington
Co-authored papers 2
Benhur Lee
Icahn School of Medicine at Mount Sinai
Co-authored papers 2
Viviana Simon
Icahn School of Medicine at Mount Sinai
Co-authored papers 1
Jonathan Klein
Co-authored papers 1
Kai Xu
Co-authored papers 1
Shiv Gandhi
Co-authored papers 1
Jan Rehwinkel
MRC Weatherall Institute of Molecular Medicine, University of Oxford
Co-authored papers 1
Zhen Li
Co-authored papers 1
Alain Sewer
Universitat Basel
Co-authored papers 1
Alessandro Sette
Center for Infectious Disease and Vaccine Research, La Jolla Institute for Immunology
Co-authored papers 1
Ariktha Srivathsan
Co-authored papers 1
Paula Montero Llopis
Co-authored papers 1
Arvind H Patel
MRC-University of Glasgow Centre for Virus Research
Co-authored papers 1
Release 1.2