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Author Details
Full Name
Justin T Biel
Affiliation
University of California san francisco
ORCID
Career Start Year
2015
Papers
10
H Index
10
Expertise
CM4AI Collaborator
Trey Ideker (CM4AI)
PMID
Paper Title
Journal Title
Published Year
36881464
Room-temperature crystallography reveals altered binding of small-molecule fragments to PTP1B.
Elife
2023
36240280
Ensemble-function relationships to dissect mechanisms of enzyme catalysis.
Sci Adv
2022
33853786
Fragment binding to the Nsp3 macrodomain of SARS-CoV-2 identified through crystallographic screening and computational docking.
Sci Adv
2021
32148858
Comparing serial X-ray crystallography and microcrystal electron diffraction (MicroED) as methods for routine structure determination from small macromolecular crystals.
IUCrJ
2020
33376217
Assessment of enzyme active site positioning and tests of catalytic mechanisms through X-ray-derived conformational ensembles.
Proc Natl Acad Sci U S A
2020
33060197
Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms.
Science
2020
32968273
Synthetic group A streptogramin antibiotics that overcome Vat resistance.
Nature
2020
29877794
An expanded allosteric network in PTP1B by multitemperature crystallography, fragment screening, and covalent tethering.
Elife
2018
28416112
Flexibility and Design: Conformational Heterogeneity along the Evolutionary Trajectory of a Redesigned Ubiquitin.
Structure
2017
25539415
Keep on moving: discovering and perturbing the conformational dynamics of enzymes.
Acc Chem Res
2015
1 - 10 of 10
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