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Author Details

Jiguang Wang
The Hong Kong University of Science and Technology
2012
45
25
PMIDPaper TitleJournal TitlePublished Year
36598983scONE-seq: A single-cell multi-omics method enables simultaneous dissection of phenotype and genotype heterogeneity from frozen tumors.Sci Adv2023
37652019Tumor-associated monocytes promote mesenchymal transformation through EGFR signaling in glioma.Cell Rep Med2023
36915208Pharmacogenomic profiling reveals molecular features of chemotherapy resistance in IDH wild-type primary glioblastoma.Genome Med2023
36253446Distinct molecular subtypes of papillary thyroid carcinoma and gene signature with diagnostic capability.Oncogene2022
31581092CNAPE: A Machine Learning Method for Copy Number Alteration Prediction from Gene Expression.IEEE/ACM Trans Comput Biol Bioinform2021
33742127Classifying gastric cancer using FLORA reveals clinically relevant molecular subtypes and highlights LINC01614 as a biomarker for patient prognosis.Oncogene2021
33509951Alternative Splicing of Three Genes Encoding Mechanotransduction-Complex Proteins in Auditory Hair Cells.eNeuro2021
33891857Somatic MAP3K3 mutation defines a subclass of cerebral cavernous malformation.Am J Hum Genet2021
33526923Noncoding RNA processing by DIS3 regulates chromosomal architecture and somatic hypermutation in B cells.Nat Genet2021
34530633De Novo Germline and Somatic Variants Convergently Promote Endothelial-to-Mesenchymal Transition in Simplex Brain Arteriovenous Malformation.Circ Res2021
34795255Machine learning of genomic features in organotropic metastases stratifies progression risk of primary tumors.Nat Commun2021
33166616Clinical practice guidelines for the management of adult diffuse gliomas.Cancer Lett2021
32348748Structural Basis for the High-Affinity Interaction between CASK and Mint1.Structure2020
32034089Noncoding RNA transcription alters chromosomal topology to promote isotype-specific class switch recombination.Sci Immunol2020
33225311Genomic characterization of HIV-associated plasmablastic lymphoma identifies pervasive mutations in the JAK-STAT pathway.Blood Cancer Discov2020
32753598MGMT genomic rearrangements contribute to chemotherapy resistance in gliomas.Nat Commun2020
32188705Mutations in the RNA Splicing Factor SF3B1 Promote Tumorigenesis through MYC Stabilization.Cancer Discov2020
29440233Comprehensive characterisation of compartment-specific long non-coding RNAs associated with pancreatic ductal adenocarcinoma.Gut2019
31586689Deciphering Brain Complexity Using Single-cell Sequencing.Genomics Proteomics Bioinformatics2019
31383760Repurposing dasatinib for diffuse large B cell lymphoma.Proc Natl Acad Sci U S A2019
31607563The Long Noncoding RNA Paupar Modulates PAX6 Regulatory Activities to Promote Alpha Cell Development and Function.Cell Metab2019
31371383Dynamic MAPK signaling activity underlies a transition from growth arrest to proliferation in <i>Drosophila scribble</i> mutant tumors.Dis Model Mech2019
28924243Refined karyotype-based prognostic stratification of chronic lymphocytic leukemia with a low- and very-low-risk genetic profile.Leukemia2018
30343896Mutational Landscape of Secondary Glioblastoma Guides MET-Targeted Trial in Brain Tumor.Cell2018
30262818Pharmacogenomic landscape of patient-derived tumor cells informs precision oncology therapy.Nat Genet2018
29632085Increased <i>HOXA5</i> expression provides a selective advantage for gain of whole chromosome 7 in IDH wild-type glioblastoma.Genes Dev2018
29365086Genetic landscape of ultra-stable chronic lymphocytic leukemia patients.Ann Oncol2018
28889947An NF-κB Transcription-Factor-Dependent Lineage-Specific Transcriptional Program Promotes Regulatory T Cell Identity and Function.Immunity2017
28263318Spatiotemporal genomic architecture informs precision oncology in glioblastoma.Nat Genet2017
29020613RNA Exosome Complex-Mediated Control of Redox Status in Pluripotent Stem Cells.Stem Cell Reports2017
29263839Identification of potentially oncogenic alterations from tumor-only samples reveals Fanconi anemia pathway mutations in bladder carcinomas.NPJ Genom Med2017
26824661Molecular Profiling Reveals Biologically Discrete Subsets and Pathways of Progression in Diffuse Glioma.Cell2016
26597680Inter- and intra-patient clonal and subclonal heterogeneity of chronic lymphocytic leukaemia: evidences from circulating and lymph nodal compartments.Br J Haematol2016
27304073Kinase-dead ATM protein is highly oncogenic and can be preferentially targeted by Topo-isomerase I inhibitors.Elife2016
27270107Clonal evolution of glioblastoma under therapy.Nat Genet2016
26883104Prognostic and therapeutic role of targetable lesions in B-lineage acute lymphoblastic leukemia without recurrent fusion genes.Oncotarget2016
25957685RNA exosome-regulated long non-coding RNA transcription controls super-enhancer activity.Cell2015
26527007Transcriptomics Identify CD9 as a Marker of Murine IL-10-Competent Regulatory B Cells.Cell Rep2015
25941339An information theoretic method to identify combinations of genomic alterations that promote glioblastoma.J Mol Cell Biol2015
24501221Clinical impact of small TP53 mutated subclones in chronic lymphocytic leukemia.Blood2014
25496728Tumor evolutionary directed graphs and the history of chronic lymphocytic leukemia.Elife2014
25119026Noncoding RNA transcription targets AID to divergently transcribed loci in B cells.Nature2014
23964096E3-ubiquitin ligase Nedd4 determines the fate of AID-associated RNA polymerase II in B cells.Genes Dev2013
24127483Genetic lesions associated with chronic lymphocytic leukemia transformation to Richter syndrome.J Exp Med2013
22891273The coding genome of splenic marginal zone lymphoma: activation of NOTCH2 and other pathways regulating marginal zone development.J Exp Med2012
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Collaborators

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Columbia University Vagelos College of Physicians and Surgeons
Co-authored papers 27
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Columbia University Medical Center
Co-authored papers 7
Robin Fo??
Sapienza University.
Co-authored papers 7
Zhaoqi Liu
University of Chinese Academy of Sciences
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Feinberg School of Medicine, Northwestern University
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University of California Riverside
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Jin-Ku Lee
Seoul National University, College of Medicine
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Daniel I S Rosenbloom
Merck & Co. Inc.
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Ho Jun Seol
Samsung Medical Center, Sungkyunkwan University School of Medicine
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Oliver Elliott
Columbia University
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Roel G W Verhaak
Yale School of Medicine
Co-authored papers 3
In-Hee Lee
Co-authored papers 3
Mykola Bordyuh
Columbia University
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Jung-Il Lee
Gangnam Severance Hospital
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Yun Jee Seo
Institute for Refractory Cancer Research, Samsung Medical Center
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Erik Ladewig
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Chul-Kee Park
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